STRINGSTRING
surE surE AFA71149.1 AFA71149.1 acsA1 acsA1 purU1 purU1 AFA71373.1 AFA71373.1 AFA71415.1 AFA71415.1 AFA71449.1 AFA71449.1 AFA71613.1 AFA71613.1 AFA71623.1 AFA71623.1 AFA71641.1 AFA71641.1 AFA71684.1 AFA71684.1 pta pta ackA ackA AFA71727.1 AFA71727.1 acsA2 acsA2 AFA71829.1 AFA71829.1 AFA71869.1 AFA71869.1 AFA71932.1 AFA71932.1 hyuA hyuA AFA71986.1 AFA71986.1 deoC deoC purU2 purU2 gpmA gpmA AFA72097.1 AFA72097.1 AFA72260.1 AFA72260.1 purN purN purH purH prs prs AFA72458.1 AFA72458.1 eno eno coaA coaA AFA72598.1 AFA72598.1 nnrD nnrD guaB guaB AFA72656.1 AFA72656.1 guaA guaA folD1 folD1 AFA72707.1 AFA72707.1 add2 add2 upp upp AFA72777.1 AFA72777.1 purK purK purE purE AFA72790.1 AFA72790.1 atpB atpB atpE atpE atpF atpF atpFH atpFH atpA atpA atpG atpG atpD atpD atpC atpC AFA72898.1 AFA72898.1 pncB pncB AFA72912.1 AFA72912.1 AFA72960.1 AFA72960.1 ndk ndk coaD coaD pyrH pyrH ribF ribF thyA thyA AFA73115.1 AFA73115.1 thyX thyX AFA73155.1 AFA73155.1 dut dut AFA73224.1 AFA73224.1 AFA73233.1 AFA73233.1 AFA73236.1 AFA73236.1 apt apt relA relA pyrB pyrB pyrC pyrC AFA73277.1 AFA73277.1 carA carA carB carB pyrF pyrF gmk gmk coaBC coaBC gapA gapA pgk pgk tpiA tpiA AFA73318.1 AFA73318.1 AFA73347.1 AFA73347.1 pyrD pyrD AFA73417.1 AFA73417.1 AFA73452.1 AFA73452.1 AFA73467.1 AFA73467.1 AFA73486.1 AFA73486.1 amacr amacr AFA73584.1 AFA73584.1 AFA73585.1 AFA73585.1 cmk cmk pyrG pyrG ppnK ppnK coaE coaE acot acot pyk pyk nadC nadC nadA nadA dltA dltA folD2 folD2 aceE aceE dgt dgt nadD nadD pfp pfp AFA74045.1 AFA74045.1 nrdF2 nrdF2 AFA74176.1 AFA74176.1 purA1 purA1 AFA74276.1 AFA74276.1 AFA74352.1 AFA74352.1 AFA74363.1 AFA74363.1 nudC nudC AFA74460.1 AFA74460.1 AFA74484.1 AFA74484.1 tmk tmk adk adk AFA74581.1 AFA74581.1 mcr mcr AFA74679.1 AFA74679.1 AFA74738.1 AFA74738.1 ldh ldh AFA74847.1 AFA74847.1 pgi pgi AFA75010.1 AFA75010.1 AFA75032.1 AFA75032.1 nadE nadE purM purM purF purF purL purL AFA75122.1 AFA75122.1 AFA75187.1 AFA75187.1 AFA75199.1 AFA75199.1 purQ purQ purS purS purC purC AFA75213.1 AFA75213.1 purB purB purD purD AFA75246.1 AFA75246.1 coaX coaX hpt hpt purT purT AFA75368.1 AFA75368.1 purA2 purA2 fba fba pyrE pyrE AFA75398.1 AFA75398.1 AFA75519.1 AFA75519.1 AFA75542.1 AFA75542.1 AFA75592.1 AFA75592.1 dcd dcd AFA75689.1 AFA75689.1 AFA75701.1 AFA75701.1 AFA75828.1 AFA75828.1 AFA75910.1 AFA75910.1 AFA75935.1 AFA75935.1 AFA75996.1 AFA75996.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
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gene neighborhood
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surEMultifunctional protein SurE. (259 aa)
AFA71149.1Putative phosphoglycerate mutase family protein. (202 aa)
acsA1Acetyl-coenzyme A synthetase AcsA. (531 aa)
purU1Formyltetrahydrofolate deformylase PurU; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (282 aa)
AFA71373.1Putative pyruvate dehydrogenase E1 component. (778 aa)
AFA71415.1Hypothetical protein. (264 aa)
AFA71449.1Putative phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (233 aa)
AFA71613.1Putative adenylate cyclase. (309 aa)
AFA71623.1Ribonucleotide reductase small subunit-like protein. (323 aa)
AFA71641.1Hypothetical protein. (342 aa)
AFA71684.1Protein of unknown function DUF3705. (285 aa)
ptaPhosphate acetyltransferase Pta; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (724 aa)
ackAAcetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa)
AFA71727.1Hypothetical protein. (387 aa)
acsA2Acetyl-coenzyme A synthetase AcsA; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa)
AFA71829.1Putative adenylyl cyclase. (526 aa)
AFA71869.1Glyoxalase-like domain-containing protein. (119 aa)
AFA71932.1Histidine triad (HIT)-like protein. (141 aa)
hyuAD-hydantoinase HyuA. (473 aa)
AFA71986.1Dihydrolipoyl dehydrogenase. (461 aa)
deoCDeoxyribose-phosphate aldolase DeoC; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (225 aa)
purU2Formyltetrahydrofolate deformylase PurU; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (318 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
AFA72097.1Hypothetical protein. (296 aa)
AFA72260.1acetoacetyl-CoA synthetase. (667 aa)
purNPhosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (211 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH. (534 aa)
prsRibose-phosphate pyrophosphokinase Prs; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)
AFA72458.1Putative nucleoside triphosphate pyrophosphohydrolase. (385 aa)
enoEnolase Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
coaAPantothenate kinase CoaA. (313 aa)
AFA72598.1Putative fatty acid desaturase. (290 aa)
nnrDPutative carbohydrate kinase, YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to [...] (478 aa)
guaBInosine-5'-monophosphate dehydrogenase GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (503 aa)
AFA72656.1Putative IMP dehydrogenase/GMP reductase. (380 aa)
guaAGMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (528 aa)
folD1Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (307 aa)
AFA72707.1Putative glutamine amidotransferase. (239 aa)
add2Adenosine deaminase Add; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (376 aa)
uppUracil phosphoribosyltransferase Upp; Belongs to the UPRTase family. (207 aa)
AFA72777.1Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (226 aa)
purKPhosphoribosylaminoimidazole carboxylase, ATPase subunit PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (397 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (189 aa)
AFA72790.1Hypothetical protein. (237 aa)
atpBATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (252 aa)
atpEATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (87 aa)
atpFATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (170 aa)
atpFHATP synthase subunit b-delta; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction; Belongs to the ATPase delta chain family. (449 aa)
atpAATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (542 aa)
atpGATP synthase gamma chain AtpG; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (315 aa)
atpDATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (482 aa)
atpCATP synthase epsilon chain AtpC; Produces ATP from ADP in the presence of a proton gradient across the membrane. (126 aa)
AFA72898.1Putative pyrazinamidase/nicotinamidase. (204 aa)
pncBNicotinate phosphoribosyltransferase PncB; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (432 aa)
AFA72912.1Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (213 aa)
AFA72960.1Hypothetical protein. (116 aa)
ndkNucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (138 aa)
coaDPhosphopantetheine adenylyltransferase CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (162 aa)
pyrHUridylate kinase PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa)
ribFRiboflavin biosynthesis protein RibF; Belongs to the ribF family. (322 aa)
thyAThymidylate synthase ThyA; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (277 aa)
AFA73115.1Hypothetical protein. (338 aa)
thyXThymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (250 aa)
AFA73155.1Hexose kinase, 1-phosphofructokinase family; Belongs to the carbohydrate kinase PfkB family. (321 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (162 aa)
AFA73224.1AP-4-A phosphorylase. (212 aa)
AFA73233.1Putative acyl-CoA thioesterase. (284 aa)
AFA73236.1Hypothetical protein. (206 aa)
aptAdenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (195 aa)
relAGTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (801 aa)
pyrBAspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (316 aa)
pyrCDihydroorotase PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (436 aa)
AFA73277.1Hypothetical protein. (206 aa)
carACarbamoyl-phosphate synthase small chain CarA; Belongs to the CarA family. (389 aa)
carBCarbamoyl-phosphate synthase large chain CarB; Belongs to the CarB family. (1116 aa)
pyrFOrotidine 5'-phosphate decarboxylase PyrF; Belongs to the OMP decarboxylase family. Type 2 subfamily. (273 aa)
gmkGuanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. (196 aa)
coaBCCoenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (432 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase GapA; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa)
pgkPhosphoglycerate kinase Pgk; Belongs to the phosphoglycerate kinase family. (403 aa)
tpiATriosephosphate isomerase TpiA; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (263 aa)
AFA73318.1Phosphoribosyltransferase. (173 aa)
AFA73347.1Putative aldolase. (285 aa)
pyrDDihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (367 aa)
AFA73417.1Hypothetical protein. (277 aa)
AFA73452.1Putative adenylyl cyclase class-3/4/guanylyl cyclase. (276 aa)
AFA73467.1Glyoxalase/bleomycin resistance protein/dioxygenase. (137 aa)
AFA73486.1Glyoxalase/bleomycin resistance protein/dioxygenase. (117 aa)
amacralpha-methylacyl-CoA racemase; Belongs to the CoA-transferase III family. (346 aa)
AFA73584.1Putative acyl-CoA transferase; Belongs to the CoA-transferase III family. (792 aa)
AFA73585.1L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family. (409 aa)
cmkCytidylate kinase Cmk. (227 aa)
pyrGCTP synthase PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (561 aa)
ppnKInorganic polyphosphate/ATP-NAD kinase PpnK; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (361 aa)
coaEdephospho-CoA kinase CoaE; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (298 aa)
acotAcyl-coenzyme A thioesterase Acot. (292 aa)
pykPyruvate kinase Pyk; Belongs to the pyruvate kinase family. (480 aa)
nadCNicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (299 aa)
nadAQuinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (353 aa)
dltADihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex. (597 aa)
folD2Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (290 aa)
aceEPyruvate dehydrogenase E1 component AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (963 aa)
dgtDeoxyguanosinetriphosphate triphosphohydrolase-like protein Dgt; Belongs to the dGTPase family. Type 2 subfamily. (429 aa)
nadDNicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (245 aa)
pfpPyrophosphate--fructose 6-phosphate 1-phosphotransferase Pfp; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (344 aa)
AFA74045.1Hypothetical protein. (247 aa)
nrdF2Ribonucleoside-diphosphate reductase subunit beta NrdF2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (336 aa)
AFA74176.1Putative thioesterase. (166 aa)
purA1Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (466 aa)
AFA74276.1formyl-CoA transferase; Belongs to the CoA-transferase III family. (414 aa)
AFA74352.1propionate-CoA ligase protein. (637 aa)
AFA74363.1Glyoxalase/bleomycin resistance protein/dioxygenase. (127 aa)
nudCNADH pyrophosphatase NudC. (308 aa)
AFA74460.1Putative NUDIX hydrolase. (160 aa)
AFA74484.1Hypothetical protein. (308 aa)
tmkThymidylate kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (219 aa)
adkAdenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (184 aa)
AFA74581.1Putative acyl-CoA thioesterase. (270 aa)
mcralpha-methylacyl-CoA racemase Mcr; Belongs to the CoA-transferase III family. (370 aa)
AFA74679.1WD-40 repeat-containing protein. (1274 aa)
AFA74738.1WD-40 repeat-containing protein. (1364 aa)
ldhL-lactate dehydrogenase Ldh; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (326 aa)
AFA74847.1Hexose kinase, 1-phosphofructokinase family; Belongs to the carbohydrate kinase PfkB family. (319 aa)
pgiGlucose-6-phosphate isomerase Pgi; Belongs to the GPI family. (557 aa)
AFA75010.1Putative adenylate/guanylate cyclase. (546 aa)
AFA75032.1Putative CoA-transferase, family III; Belongs to the CoA-transferase III family. (403 aa)
nadENAD+ synthase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (675 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase PurM. (373 aa)
purFAmidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (527 aa)
purLPhosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (763 aa)
AFA75122.1Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein. (267 aa)
AFA75187.1Putative acyl--CoA ligase. (578 aa)
AFA75199.1Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein. (463 aa)
purQPhosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (227 aa)
purSPhosphoribosylformylglycinamidine synthase, PurS subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is th [...] (79 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Belongs to the SAICAR synthetase family. (295 aa)
AFA75213.1Hypothetical protein. (145 aa)
purBAdenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (475 aa)
purDPhosphoribosylamine--glycine ligase PurD; Belongs to the GARS family. (417 aa)
AFA75246.1Putative CoA-transferase, family III; Belongs to the CoA-transferase III family. (370 aa)
coaXType III pantothenate kinase CoaX; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (266 aa)
hptHypoxanthine-guanine phosphoribosyltransferase Hpt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (189 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (546 aa)
AFA75368.1Putative adenylate cyclase. (523 aa)
purA2Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa)
fbaFructose-bisphosphate aldolase Fba; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (344 aa)
pyrEOrotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (186 aa)
AFA75398.1Putative secreted protein. (345 aa)
AFA75519.1Putative CoA-transferase, family III; Belongs to the CoA-transferase III family. (382 aa)
AFA75542.1Glyoxalase-like protein. (115 aa)
AFA75592.1CinA-like protein; Belongs to the CinA family. (157 aa)
dcdDeoxycytidine triphosphate deaminase Dcd; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (191 aa)
AFA75689.1Hypothetical protein. (130 aa)
AFA75701.1Hypothetical protein. (185 aa)
AFA75828.1CinA domain-containing protein; Belongs to the CinA family. (439 aa)
AFA75910.1Glyoxalase-like domain-containing protein. (132 aa)
AFA75935.1Hypothetical protein. (398 aa)
AFA75996.1Hypothetical protein; Belongs to the UPF0301 (AlgH) family. (225 aa)
Your Current Organism:
Gordonia polyisoprenivorans
NCBI taxonomy Id: 1112204
Other names: G. polyisoprenivorans VH2, Gordonia polyisoprenivorans VH2, Gordonia polyisoprenivorans str. VH2, Gordonia polyisoprenivorans strain VH2
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