STRINGSTRING
rpoC rpoC dnaN dnaN AFA71354.1 AFA71354.1 AFA71586.1 AFA71586.1 AFA71604.1 AFA71604.1 AFA71830.1 AFA71830.1 rmlA1 rmlA1 AFA72051.1 AFA72051.1 ispD ispD rmlA2 rmlA2 AFA72207.1 AFA72207.1 AFA72213.1 AFA72213.1 AFA72216.1 AFA72216.1 AFA72308.1 AFA72308.1 glmU glmU cysD1 cysD1 cysNC1 cysNC1 AFA72671.1 AFA72671.1 dnaE2 dnaE2 AFA72794.1 AFA72794.1 rph rph mobA mobA coaD coaD glnD glnD cdsA cdsA ribF ribF pnp pnp rpoZ rpoZ AFA73387.1 AFA73387.1 polA polA dnaE1 dnaE1 dinB1 dinB1 AFA73829.1 AFA73829.1 glnE glnE dnaG dnaG cysD2 cysD2 cysNC2 cysNC2 AFA73980.1 AFA73980.1 nadD nadD cofC cofC ligD ligD glgC glgC galT galT yshC yshC rpoA rpoA AFA74756.1 AFA74756.1 dinB dinB rpoB rpoB cysNC3 cysNC3 cysD3 cysD3 disA disA AFA75483.1 AFA75483.1 AFA75537.1 AFA75537.1 AFA75538.1 AFA75538.1 dnaX dnaX AFA75719.1 AFA75719.1 AFA75776.1 AFA75776.1 dinB-2 dinB-2 AFA76000.1 AFA76000.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1319 aa)
dnaNDNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (396 aa)
AFA71354.1Putative CBS domain-containing and cyclic nucleotide-regulated nucleotidyltransferase. (615 aa)
AFA71586.1Putative ATP-dependent DNA ligase. (812 aa)
AFA71604.1Diguanylate cyclase (GGDEF) domain-containing protein. (395 aa)
AFA71830.1DNA polymerase III delta prime subunit. (427 aa)
rmlA1Glucose-1-phosphate thymidylyltransferase RmlA; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (292 aa)
AFA72051.1Putative diguanylate cyclase (GGDEF). (384 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase IspD; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (242 aa)
rmlA2Glucose-1-phosphate thymidylyltransferase RmlA; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (291 aa)
AFA72207.1Putative glucose-1-phosphate cytidylyltransferase. (272 aa)
AFA72213.1EAL domain-containing protein. (394 aa)
AFA72216.1Putative diguanylate cyclase. (389 aa)
AFA72308.1Nucleotidyl transferase. (316 aa)
glmUBifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (500 aa)
cysD1Sulfate adenylyltransferase subunit 2. (310 aa)
cysNC1Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family. (629 aa)
AFA72671.1Putative DNA polymerase involved in DNA repair. (532 aa)
dnaE2DNA polymerase III alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1085 aa)
AFA72794.1Putative mannose-1-phosphate guanylyltransferase. (376 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (250 aa)
mobAPutative molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (214 aa)
coaDPhosphopantetheine adenylyltransferase CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (162 aa)
glnD[protein-PII] uridylyltransferase GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (864 aa)
cdsAPhosphatidate cytidylyltransferase CdsA; Belongs to the CDS family. (314 aa)
ribFRiboflavin biosynthesis protein RibF; Belongs to the ribF family. (322 aa)
pnpPolyribonucleotide nucleotidyltransferase Pnp; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (759 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (99 aa)
AFA73387.1Putative 2,3-dihydroxybenzoate-AMP ligase. (525 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (930 aa)
dnaE1DNA polymerase III alpha subunit. (1182 aa)
dinB1DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (521 aa)
AFA73829.1DNA polymerase III epsilon subunit. (622 aa)
glnEGlutamate-ammonia-ligase adenylyltransferase GlnE; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal t [...] (985 aa)
dnaGDNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (638 aa)
cysD2Sulfate adenylyltransferase subunit 2. (314 aa)
cysNC2Bifunctional enzyme CysN/CysC; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (445 aa)
AFA73980.1DNA polymerase III delta subunit. (322 aa)
nadDNicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (245 aa)
cofC2-phospho-L-lactate guanylyltransferase CofC. (256 aa)
ligDDNA polymerase LigD. (318 aa)
glgCGlucose-1-phosphate adenylyltransferase GlgC; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (398 aa)
galTGalactose-1-phosphate uridylyltransferase GalT. (382 aa)
yshCProtein YshC. (354 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (350 aa)
AFA74756.1Diguanylate cyclase (GGDEF) domain-containing protein. (555 aa)
dinBDNA polymerase IV. (373 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1171 aa)
cysNC3Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family. (615 aa)
cysD3Sulfate adenylyltransferase subunit 2. (312 aa)
disADNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process. (371 aa)
AFA75483.1Putative diguanylate cyclase (GGDEF) domain-containing membrane protein. (332 aa)
AFA75537.1Diguanylate cyclase (GGDEF) domain-containing protein. (369 aa)
AFA75538.1Diguanylate cyclase (GGDEF) domain-containing protein. (384 aa)
dnaXDNA polymerase III; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (761 aa)
AFA75719.1DNA primase, small subunit. (358 aa)
AFA75776.1Putative reverse transcriptase. (429 aa)
dinB-2DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (402 aa)
AFA76000.1tRNA nucleotidyltransferase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (490 aa)
Your Current Organism:
Gordonia polyisoprenivorans
NCBI taxonomy Id: 1112204
Other names: G. polyisoprenivorans VH2, Gordonia polyisoprenivorans VH2, Gordonia polyisoprenivorans str. VH2, Gordonia polyisoprenivorans strain VH2
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