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cobIJ | Cobalamin biosynthesis protein CobIJ. (507 aa) | ||||
AFA71166.1 | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (318 aa) | ||||
AFA71513.1 | Putative aldo/keto reductase. (276 aa) | ||||
thiE | Thiamine-phosphate pyrophosphorylase ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). (177 aa) | ||||
thiO | Putative glycine oxidase ThiO. (370 aa) | ||||
thiS | Thiamine biosynthesis protein ThiS. (65 aa) | ||||
thiG | Thiazole synthase ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (259 aa) | ||||
AFA71769.1 | CobW family protein. (411 aa) | ||||
AFA71835.1 | NMT1/THI5-like protein. (367 aa) | ||||
thiD | Phosphomethylpyrimidine kinase ThiD. (290 aa) | ||||
thiC | Phosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (563 aa) | ||||
AFA72369.1 | Cobalamin synthesis CobW-like protein. (446 aa) | ||||
AFA72701.1 | Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa) | ||||
cobA1 | cob(I)yrinic acid a,c-diamide adenosyltransferase CobA; Belongs to the Cob(I)alamin adenosyltransferase family. (204 aa) | ||||
cbiM | Putative cobalamin (vitamin B12) biosynthesis protein CbiM. (241 aa) | ||||
AFA72867.1 | Putative membrane protein. (139 aa) | ||||
cobQ | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (528 aa) | ||||
cobA2 | cob(I)yrinic acid a,c-diamide adenosyltransferase CobA. (205 aa) | ||||
ribF | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. (322 aa) | ||||
AFA73162.1 | Putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (412 aa) | ||||
dxs | 1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (663 aa) | ||||
AFA73204.1 | Putative riboflavin-specific deaminase. (254 aa) | ||||
pdxS | Pyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (282 aa) | ||||
pdxT | Glutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (203 aa) | ||||
ribD | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (343 aa) | ||||
ribE | Riboflavin synthase alpha chain RibE. (220 aa) | ||||
ribBA | Riboflavin biosynthesis protein RibBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (449 aa) | ||||
ribH | 6,7-dimethyl-8-ribityllumazine synthase RibH; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (171 aa) | ||||
AFA73300.1 | Protein of unknown function DUF2581. (152 aa) | ||||
AFA73321.1 | Hypothetical protein. (129 aa) | ||||
cobL | precorrin-6Y C(5,15)-methyltransferase. (427 aa) | ||||
cobM | Precorrin-4 C(11)-methyltransferase CobM. (265 aa) | ||||
cobK | precorrin-6A reductase CobK. (244 aa) | ||||
cobH | precorrin-8X methylmutase CobH. (221 aa) | ||||
cobN | Aerobic cobaltochelatase subunit CobN. (1218 aa) | ||||
pdxK | Pyridoxine kinase PdxK. (263 aa) | ||||
AFA73594.1 | Glyoxalase/bleomycin resistance protein/dioxygenase. (127 aa) | ||||
AFA73618.1 | Thiamin pyrophosphokinase, catalytic subunit. (395 aa) | ||||
bioB | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (346 aa) | ||||
bioD | Dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (248 aa) | ||||
bioF | 8-amino-7-oxononanoate synthase. (396 aa) | ||||
bioA | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (432 aa) | ||||
cobT | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase CobT; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (615 aa) | ||||
cobS | Cobalamin synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (267 aa) | ||||
panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (298 aa) | ||||
cobD | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (295 aa) | ||||
thiL | Thiamine-monophosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (377 aa) | ||||
AFA74231.1 | Cobalamin synthesis protein/P47K. (382 aa) | ||||
AFA74435.1 | Putative 2,5-didehydrogluconate reductase. (276 aa) | ||||
AFA74656.1 | Putative creatinine amidohydrolase. (237 aa) | ||||
cobF | precorrin-6A synthase (deacetylating). (252 aa) | ||||
AFA74920.1 | Putative FAD-dependent oxidoreductase. (436 aa) | ||||
pdxH | Pyridoxine/pyridoxamine 5'-phosphate oxidase PdxH; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (249 aa) | ||||
serC | Phosphoserine aminotransferase SerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (380 aa) | ||||
AFA75079.1 | Putative aminotransferase. (296 aa) | ||||
panD | Aspartate 1-decarboxylase PanD; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (144 aa) | ||||
panC | Pantothenate synthetase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (306 aa) | ||||
folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. (185 aa) | ||||
folB | Dihydroneopterin aldolase FolB; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (123 aa) | ||||
folP2 | Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (295 aa) | ||||
AFA75541.1 | Putative oxidoreductase, aldo/keto reductase family. (272 aa) | ||||
AFA75698.1 | CobB/CobQ domain-containing protein. (239 aa) | ||||
panE | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (301 aa) |