STRINGSTRING
AFA72835.1 AFA72835.1 ggt ggt acsA1 acsA1 pta pta ackA ackA thiE thiE thiO thiO thiS thiS thiG thiG asd asd acsA2 acsA2 AFA71835.1 AFA71835.1 AFA71865.1 AFA71865.1 thiD thiD thiC thiC mshA mshA AFA72142.1 AFA72142.1 AFA72208.1 AFA72208.1 AFA72260.1 AFA72260.1 cysD1 cysD1 cysNC1 cysNC1 cysB cysB metB metB folD1 folD1 metX metX AFA72691.1 AFA72691.1 AFA72701.1 AFA72701.1 AFA72765.1 AFA72765.1 metE metE AFA72790.1 AFA72790.1 hom hom AFA72843.1 AFA72843.1 AFA72905.1 AFA72905.1 cysO cysO cysM cysM AFA72929.1 AFA72929.1 AFA73162.1 AFA73162.1 dxs dxs metK metK mshC mshC metH metH cobG cobG pdxK pdxK cysJ cysJ AFA73594.1 AFA73594.1 AFA73618.1 AFA73618.1 bioB bioB bioD bioD bioF bioF bioA bioA metF metF lipA lipA folD2 folD2 cysH cysH cysD2 cysD2 thiL thiL AFA74057.1 AFA74057.1 mshB mshB AFA74352.1 AFA74352.1 mOCS3 mOCS3 AFA74595.1 AFA74595.1 mshD mshD AFA75087.1 AFA75087.1 cysNC3 cysNC3 cysD3 cysD3 AFA75187.1 AFA75187.1 metZ metZ
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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AFA72835.1Putative glutamine amidotransferase, class-II. (292 aa)
ggtGamma-glutamyltransferase Ggt. (653 aa)
acsA1Acetyl-coenzyme A synthetase AcsA. (531 aa)
ptaPhosphate acetyltransferase Pta; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (724 aa)
ackAAcetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa)
thiEThiamine-phosphate pyrophosphorylase ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). (177 aa)
thiOPutative glycine oxidase ThiO. (370 aa)
thiSThiamine biosynthesis protein ThiS. (65 aa)
thiGThiazole synthase ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (259 aa)
asdAspartate-semialdehyde dehydrogenase Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (342 aa)
acsA2Acetyl-coenzyme A synthetase AcsA; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa)
AFA71835.1NMT1/THI5-like protein. (367 aa)
AFA71865.1Putative methyltransferase. (322 aa)
thiDPhosphomethylpyrimidine kinase ThiD. (290 aa)
thiCPhosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (563 aa)
mshAD-inositol-3-phosphate glycosyltransferase MshA; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. (446 aa)
AFA72142.1Putative pyridoxal-phosphate dependent protein. (376 aa)
AFA72208.1Putative GlcNAc-PI de-N-acetylase. (218 aa)
AFA72260.1acetoacetyl-CoA synthetase. (667 aa)
cysD1Sulfate adenylyltransferase subunit 2. (310 aa)
cysNC1Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family. (629 aa)
cysBCystathionine beta-synthase CysB. (466 aa)
metBCystathionine gamma-synthase MetB. (384 aa)
folD1Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (307 aa)
metXHomoserine O-acetyltransferase MetX; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (382 aa)
AFA72691.1O-acetylhomoserine (thiol)-lyase. (444 aa)
AFA72701.1Aminotransferase, class III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
AFA72765.1Putative cobalamin-independent methionine synthase. (341 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase MetE; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (762 aa)
AFA72790.1Hypothetical protein. (237 aa)
homHomoserine dehydrogenase Hom. (444 aa)
AFA72843.1Putative sulfite reductase [NADPH] flavoprotein, alpha-component. (616 aa)
AFA72905.1Putative CysO-cysteine peptidase. (135 aa)
cysOSulfur carrier protein CysO. (94 aa)
cysMCysteine synthase B. (324 aa)
AFA72929.1Putative cystathionine or methionine gamma-lyase. (398 aa)
AFA73162.1Putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (412 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (663 aa)
metKS-adenosylmethionine synthase MetK; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (403 aa)
mshCL-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase MshC; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (413 aa)
metHMethionine synthase MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1203 aa)
cobGprecorrin-3B synthase CobG. (397 aa)
pdxKPyridoxine kinase PdxK. (263 aa)
cysJSulfite reductase [NADPH] flavoprotein alpha-component CysJ. (538 aa)
AFA73594.1Glyoxalase/bleomycin resistance protein/dioxygenase. (127 aa)
AFA73618.1Thiamin pyrophosphokinase, catalytic subunit. (395 aa)
bioBBiotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (346 aa)
bioDDethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (248 aa)
bioF8-amino-7-oxononanoate synthase. (396 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (432 aa)
metF5,10-methylenetetrahydrofolate reductase MetF; Belongs to the methylenetetrahydrofolate reductase family. (319 aa)
lipALipoyl synthase LipA; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (327 aa)
folD2Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (290 aa)
cysHPhosphoadenosine phosphosulfate reductase CysH; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (249 aa)
cysD2Sulfate adenylyltransferase subunit 2. (314 aa)
thiLThiamine-monophosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (377 aa)
AFA74057.1vitamin-B12 independent methionine synthase. (339 aa)
mshB1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- gluc opyranosidedeacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. (302 aa)
AFA74352.1propionate-CoA ligase protein. (637 aa)
mOCS3Adenylyltransferase and sulfurtransferase MOCS3. (384 aa)
AFA74595.1LmbE-like protein. (225 aa)
mshDMycothiol acetyltransferase MshD; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. (311 aa)
AFA75087.1Hypothetical protein. (502 aa)
cysNC3Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family. (615 aa)
cysD3Sulfate adenylyltransferase subunit 2. (312 aa)
AFA75187.1Putative acyl--CoA ligase. (578 aa)
metZPutative O-succinylhomoserine sulfhydrylase MetZ; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (399 aa)
Your Current Organism:
Gordonia polyisoprenivorans
NCBI taxonomy Id: 1112204
Other names: G. polyisoprenivorans VH2, Gordonia polyisoprenivorans VH2, Gordonia polyisoprenivorans str. VH2, Gordonia polyisoprenivorans strain VH2
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