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| | AFA75199.1 | Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein. (463 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (227 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, PurS subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is th [...] (79 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Belongs to the SAICAR synthetase family. (295 aa) |
| | AFA75213.1 | Hypothetical protein. (145 aa) |
| | purB | Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (475 aa) |
| | purD | Phosphoribosylamine--glycine ligase PurD; Belongs to the GARS family. (417 aa) |
| | AFA75246.1 | Putative CoA-transferase, family III; Belongs to the CoA-transferase III family. (370 aa) |
| | coaX | Type III pantothenate kinase CoaX; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (266 aa) |
| | hpt | Hypoxanthine-guanine phosphoribosyltransferase Hpt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (189 aa) |
| | alc | Allantoicase Alc; Belongs to the allantoicase family. (345 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (546 aa) |
| | AFA75368.1 | Putative adenylate cyclase. (523 aa) |
| | purA2 | Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa) |
| | fba | Fructose-bisphosphate aldolase Fba; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (344 aa) |
| | pyrE | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (186 aa) |
| | AFA75398.1 | Putative secreted protein. (345 aa) |
| | AFA75519.1 | Putative CoA-transferase, family III; Belongs to the CoA-transferase III family. (382 aa) |
| | AFA75542.1 | Glyoxalase-like protein. (115 aa) |
| | AFA75592.1 | CinA-like protein; Belongs to the CinA family. (157 aa) |
| | ugd2 | UDP-glucose 6-dehydrogenase Ugd. (478 aa) |
| | dcd | Deoxycytidine triphosphate deaminase Dcd; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (191 aa) |
| | AFA75684.1 | AIR synthase-like protein. (485 aa) |
| | AFA75689.1 | Hypothetical protein. (130 aa) |
| | AFA75701.1 | Hypothetical protein. (185 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (422 aa) |
| | AFA75828.1 | CinA domain-containing protein; Belongs to the CinA family. (439 aa) |
| | AFA75910.1 | Glyoxalase-like domain-containing protein. (132 aa) |
| | AFA75935.1 | Hypothetical protein. (398 aa) |
| | AFA75996.1 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. (225 aa) |
| | nadC | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (299 aa) |
| | pyk | Pyruvate kinase Pyk; Belongs to the pyruvate kinase family. (480 aa) |
| | acot | Acyl-coenzyme A thioesterase Acot. (292 aa) |
| | coaE | dephospho-CoA kinase CoaE; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (298 aa) |
| | ppnK | Inorganic polyphosphate/ATP-NAD kinase PpnK; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (361 aa) |
| | pyrG | CTP synthase PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (561 aa) |
| | nudF | ADP-ribose pyrophosphatase NudF. (218 aa) |
| | cmk | Cytidylate kinase Cmk. (227 aa) |
| | AFA73585.1 | L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family. (409 aa) |
| | AFA73584.1 | Putative acyl-CoA transferase; Belongs to the CoA-transferase III family. (792 aa) |
| | amacr | alpha-methylacyl-CoA racemase; Belongs to the CoA-transferase III family. (346 aa) |
| | AFA73486.1 | Glyoxalase/bleomycin resistance protein/dioxygenase. (117 aa) |
| | AFA73467.1 | Glyoxalase/bleomycin resistance protein/dioxygenase. (137 aa) |
| | AFA73452.1 | Putative adenylyl cyclase class-3/4/guanylyl cyclase. (276 aa) |
| | AFA73417.1 | Hypothetical protein. (277 aa) |
| | pyrD | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (367 aa) |
| | AFA73347.1 | Putative aldolase. (285 aa) |
| | AFA73318.1 | Phosphoribosyltransferase. (173 aa) |
| | tpiA | Triosephosphate isomerase TpiA; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (263 aa) |
| | pgk | Phosphoglycerate kinase Pgk; Belongs to the phosphoglycerate kinase family. (403 aa) |
| | gapA | Glyceraldehyde-3-phosphate dehydrogenase GapA; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (338 aa) |
| | coaBC | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (432 aa) |
| | gmk | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. (196 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase PyrF; Belongs to the OMP decarboxylase family. Type 2 subfamily. (273 aa) |
| | carB | Carbamoyl-phosphate synthase large chain CarB; Belongs to the CarB family. (1116 aa) |
| | carA | Carbamoyl-phosphate synthase small chain CarA; Belongs to the CarA family. (389 aa) |
| | AFA73277.1 | Hypothetical protein. (206 aa) |
| | pyrC | Dihydroorotase PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (436 aa) |
| | pyrB | Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (316 aa) |
| | relA | GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (801 aa) |
| | apt | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (195 aa) |
| | AFA73236.1 | Hypothetical protein. (206 aa) |
| | AFA73233.1 | Putative acyl-CoA thioesterase. (284 aa) |
| | AFA73224.1 | AP-4-A phosphorylase. (212 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (162 aa) |
| | AFA73155.1 | Hexose kinase, 1-phosphofructokinase family; Belongs to the carbohydrate kinase PfkB family. (321 aa) |
| | thyX | Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (250 aa) |
| | AFA73120.1 | Putative HAD-superfamily hydrolase, subfamily IIB. (254 aa) |
| | AFA73115.1 | Hypothetical protein. (338 aa) |
| | thyA | Thymidylate synthase ThyA; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (277 aa) |
| | ribF | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. (322 aa) |
| | AFA73072.1 | Putative acetyltransferase, GNAT family. (165 aa) |
| | pyrH | Uridylate kinase PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa) |
| | AFA73048.1 | Hypothetical protein. (324 aa) |
| | coaD | Phosphopantetheine adenylyltransferase CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (162 aa) |
| | ndk | Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (138 aa) |
| | AFA72960.1 | Hypothetical protein. (116 aa) |
| | AFA72912.1 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (213 aa) |
| | pncB | Nicotinate phosphoribosyltransferase PncB; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (432 aa) |
| | AFA72898.1 | Putative pyrazinamidase/nicotinamidase. (204 aa) |
| | atpC | ATP synthase epsilon chain AtpC; Produces ATP from ADP in the presence of a proton gradient across the membrane. (126 aa) |
| | atpD | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (482 aa) |
| | atpG | ATP synthase gamma chain AtpG; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (315 aa) |
| | atpA | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (542 aa) |
| | atpFH | ATP synthase subunit b-delta; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction; Belongs to the ATPase delta chain family. (449 aa) |
| | atpF | ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (170 aa) |
| | atpE | ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (87 aa) |
| | atpB | ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (252 aa) |
| | rmlD | dTDP-4-dehydrorhamnose reductase RmlD; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (319 aa) |
| | AFA72790.1 | Hypothetical protein. (237 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (189 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (397 aa) |
| | AFA72777.1 | Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (226 aa) |
| | AFA72769.1 | Xanthine/uracil permease. (662 aa) |
| | AFA72768.1 | Putative OHCU decarboxylase. (173 aa) |
| | AFA72767.1 | Hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (108 aa) |
| | punA | Purine nucleoside phosphorylase PunA; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (267 aa) |
| | upp | Uracil phosphoribosyltransferase Upp; Belongs to the UPRTase family. (207 aa) |
| | add2 | Adenosine deaminase Add; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (376 aa) |
| | AFA71613.1 | Putative adenylate cyclase. (309 aa) |
| | AFA71623.1 | Ribonucleotide reductase small subunit-like protein. (323 aa) |
| | AFA71641.1 | Hypothetical protein. (342 aa) |
| | AFA71684.1 | Protein of unknown function DUF3705. (285 aa) |
| | pta | Phosphate acetyltransferase Pta; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (724 aa) |
| | ackA | Acetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa) |
| | AFA71727.1 | Hypothetical protein. (387 aa) |
| | AFA71804.1 | NUDIX hydrolase. (279 aa) |
| | acsA2 | Acetyl-coenzyme A synthetase AcsA; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa) |
| | AFA71829.1 | Putative adenylyl cyclase. (526 aa) |
| | rmlB1 | dTDP-glucose 4,6-dehydratase RmlB; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (334 aa) |
| | rmlC1 | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC. (206 aa) |
| | AFA71869.1 | Glyoxalase-like domain-containing protein. (119 aa) |
| | AFA71932.1 | Histidine triad (HIT)-like protein. (141 aa) |
| | hyuA | D-hydantoinase HyuA. (473 aa) |
| | AFA71986.1 | Dihydrolipoyl dehydrogenase. (461 aa) |
| | deoC | Deoxyribose-phosphate aldolase DeoC; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (225 aa) |
| | purU2 | Formyltetrahydrofolate deformylase PurU; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (318 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa) |
| | AFA72097.1 | Hypothetical protein. (296 aa) |
| | rmlB2 | dTDP-glucose 4,6-dehydratase RmlB; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (334 aa) |
| | rmlC2 | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC. (180 aa) |
| | ugd1 | UDP-glucose 6-dehydrogenase Ugd. (433 aa) |
| | AFA72210.1 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (183 aa) |
| | AFA72260.1 | acetoacetyl-CoA synthetase. (667 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (211 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH. (534 aa) |
| | AFA72308.1 | Nucleotidyl transferase. (316 aa) |
| | prs | Ribose-phosphate pyrophosphokinase Prs; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa) |
| | glmU | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (500 aa) |
| | AFA72458.1 | Putative nucleoside triphosphate pyrophosphohydrolase. (385 aa) |
| | eno | Enolase Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | AFA72561.1 | Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (250 aa) |
| | coaA | Pantothenate kinase CoaA. (313 aa) |
| | AFA72598.1 | Putative fatty acid desaturase. (290 aa) |
| | nnrD | Putative carbohydrate kinase, YjeF family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to [...] (478 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (503 aa) |
| | AFA72656.1 | Putative IMP dehydrogenase/GMP reductase. (380 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (528 aa) |
| | folD1 | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (307 aa) |
| | AFA72707.1 | Putative glutamine amidotransferase. (239 aa) |
| | cdd | Cytidine deaminase Cdd. (139 aa) |
| | surE | Multifunctional protein SurE. (259 aa) |
| | deoA | Thymidine phosphorylase DeoA. (448 aa) |
| | AFA71149.1 | Putative phosphoglycerate mutase family protein. (202 aa) |
| | AFA71225.1 | Isochorismatase family protein. (194 aa) |
| | acsA1 | Acetyl-coenzyme A synthetase AcsA. (531 aa) |
| | purU1 | Formyltetrahydrofolate deformylase PurU; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (282 aa) |
| | AFA71373.1 | Putative pyruvate dehydrogenase E1 component. (778 aa) |
| | AFA71415.1 | Hypothetical protein. (264 aa) |
| | AFA71449.1 | Putative phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (233 aa) |
| | tmk | Thymidylate kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (219 aa) |
| | adk | Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (184 aa) |
| | AFA74581.1 | Putative acyl-CoA thioesterase. (270 aa) |
| | mcr | alpha-methylacyl-CoA racemase Mcr; Belongs to the CoA-transferase III family. (370 aa) |
| | AFA74679.1 | WD-40 repeat-containing protein. (1274 aa) |
| | AFA74738.1 | WD-40 repeat-containing protein. (1364 aa) |
| | ldh | L-lactate dehydrogenase Ldh; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (326 aa) |
| | AFA74847.1 | Hexose kinase, 1-phosphofructokinase family; Belongs to the carbohydrate kinase PfkB family. (319 aa) |
| | pgi | Glucose-6-phosphate isomerase Pgi; Belongs to the GPI family. (557 aa) |
| | AFA74921.1 | XdhC family protein. (359 aa) |
| | AFA75010.1 | Putative adenylate/guanylate cyclase. (546 aa) |
| | AFA75032.1 | Putative CoA-transferase, family III; Belongs to the CoA-transferase III family. (403 aa) |
| | nadE | NAD+ synthase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (675 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase PurM. (373 aa) |
| | purF | Amidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (527 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (763 aa) |
| | AFA75122.1 | Glyoxalase/bleomycin resistance protein/dioxygenase superfamily protein. (267 aa) |
| | AFA75185.1 | Isochorismatase family protein. (210 aa) |
| | AFA75187.1 | Putative acyl--CoA ligase. (578 aa) |
| | AFA74484.1 | Hypothetical protein. (308 aa) |
| | AFA74460.1 | Putative NUDIX hydrolase. (160 aa) |
| | AFA74422.1 | Isochorismatase family protein. (204 aa) |
| | nudC | NADH pyrophosphatase NudC. (308 aa) |
| | AFA74363.1 | Glyoxalase/bleomycin resistance protein/dioxygenase. (127 aa) |
| | AFA74352.1 | propionate-CoA ligase protein. (637 aa) |
| | AFA74276.1 | formyl-CoA transferase; Belongs to the CoA-transferase III family. (414 aa) |
| | purA1 | Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (466 aa) |
| | AFA74227.1 | Putative nucleosidase. (195 aa) |
| | AFA74176.1 | Putative thioesterase. (166 aa) |
| | AFA74121.1 | Glycosyl transferase. (353 aa) |
| | manA | Mannose-6-phosphate isomerase ManA. (415 aa) |
| | nrdF2 | Ribonucleoside-diphosphate reductase subunit beta NrdF2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (336 aa) |
| | AFA74045.1 | Hypothetical protein. (247 aa) |
| | pfp | Pyrophosphate--fructose 6-phosphate 1-phosphotransferase Pfp; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (344 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (245 aa) |
| | AFA73944.1 | Putative cytidine deaminase. (115 aa) |
| | dgt | Deoxyguanosinetriphosphate triphosphohydrolase-like protein Dgt; Belongs to the dGTPase family. Type 2 subfamily. (429 aa) |
| | aceE | Pyruvate dehydrogenase E1 component AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (963 aa) |
| | folD2 | Bifunctional protein FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (290 aa) |
| | dltA | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex. (597 aa) |
| | nadA | Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (353 aa) |
