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| | AFA76004.1 | MviN domain-containing protein. (1273 aa) |
| | pbpA | Penicillin-binding protein A. (494 aa) |
| | AFA71123.1 | Putative class II glutamine amidotransferase. (298 aa) |
| | acsA1 | Acetyl-coenzyme A synthetase AcsA. (531 aa) |
| | purU1 | Formyltetrahydrofolate deformylase PurU; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (282 aa) |
| | AFA71392.1 | Glycosyl transferase, family 39. (685 aa) |
| | AFA71483.1 | Putative esterase. (340 aa) |
| | AFA71517.1 | Putative transmembrane protein. (485 aa) |
| | AFA71613.1 | Putative adenylate cyclase. (309 aa) |
| | AFA71623.1 | Ribonucleotide reductase small subunit-like protein. (323 aa) |
| | AFA71630.1 | Putative penicillin-binding protein. (553 aa) |
| | pta | Phosphate acetyltransferase Pta; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (724 aa) |
| | ackA | Acetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (403 aa) |
| | AFA71727.1 | Hypothetical protein. (387 aa) |
| | AFA71739.1 | Glycosyl transferase family 28 protein. (462 aa) |
| | AFA71748.1 | Putative transmembrane protein. (430 aa) |
| | AFA71790.1 | Putative calcineurin-like phosphoesterase. (332 aa) |
| | acsA2 | Acetyl-coenzyme A synthetase AcsA; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa) |
| | rmlC1 | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC. (206 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase MurB; Cell wall formation. (359 aa) |
| | purU2 | Formyltetrahydrofolate deformylase PurU; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (318 aa) |
| | AFA72037.1 | Putative L,D-transpeptidase. (418 aa) |
| | AFA72075.1 | Putative membrane protein. (555 aa) |
| | mshA | D-inositol-3-phosphate glycosyltransferase MshA; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. (446 aa) |
| | AFA72101.1 | Putative NAD-dependent epimerase/dehydratase. (350 aa) |
| | AFA72167.1 | Putative acyltransferase. (690 aa) |
| | rmlC2 | dTDP-4-dehydrorhamnose 3,5-epimerase RmlC. (180 aa) |
| | ugd1 | UDP-glucose 6-dehydrogenase Ugd. (433 aa) |
| | AFA72181.1 | Putative acyltransferase. (390 aa) |
| | AFA72182.1 | Putative exopolysaccharide synthesis protein. (462 aa) |
| | AFA72183.1 | Hypothetical protein. (601 aa) |
| | AFA72198.1 | Putative glycosyl transferase, group 1. (356 aa) |
| | AFA72201.1 | Putative glycosyl transferase, group 1. (379 aa) |
| | AFA72202.1 | Putative glycosyl transferase, group 1. (374 aa) |
| | AFA72208.1 | Putative GlcNAc-PI de-N-acetylase. (218 aa) |
| | AFA72209.1 | NAD-dependent epimerase/dehydratase family protein. (342 aa) |
| | AFA72210.1 | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (183 aa) |
| | AFA72228.1 | Glycosyl transferase, group 1. (387 aa) |
| | AFA72260.1 | acetoacetyl-CoA synthetase. (667 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (211 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase PurH. (534 aa) |
| | AFA72277.1 | Putative mannosyltransferase. (784 aa) |
| | AFA72386.1 | Putative dolichyl-phosphate-mannose-protein mannosyltransferase. (532 aa) |
| | prs | Ribose-phosphate pyrophosphokinase Prs; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa) |
| | glmU | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (500 aa) |
| | AFA72561.1 | Putative membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (250 aa) |
| | coaA | Pantothenate kinase CoaA. (313 aa) |
| | AFA72598.1 | Putative fatty acid desaturase. (290 aa) |
| | AFA72611.1 | YkuD domain-containing protein. (332 aa) |
| | glmS2 | Glucosamine-fructose-6-phosphate aminotransferase GlmS; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (620 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (503 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (528 aa) |
| | AFA72700.1 | Putative D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (425 aa) |
| | AFA72707.1 | Putative glutamine amidotransferase. (239 aa) |
| | upp | Uracil phosphoribosyltransferase Upp; Belongs to the UPRTase family. (207 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (397 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit PurE; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (189 aa) |
| | AFA72790.1 | Hypothetical protein. (237 aa) |
| | rmlD | dTDP-4-dehydrorhamnose reductase RmlD; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (319 aa) |
| | atpB | ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (252 aa) |
| | atpE | ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (87 aa) |
| | atpF | ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (170 aa) |
| | atpFH | ATP synthase subunit b-delta; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction; Belongs to the ATPase delta chain family. (449 aa) |
| | atpA | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (542 aa) |
| | atpG | ATP synthase gamma chain AtpG; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (315 aa) |
| | atpD | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (482 aa) |
| | atpC | ATP synthase epsilon chain AtpC; Produces ATP from ADP in the presence of a proton gradient across the membrane. (126 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (418 aa) |
| | murI | Glutamate racemase MurI; Provides the (R)-glutamate required for cell wall biosynthesis. (247 aa) |
| | AFA72942.1 | YkuD domain-containing protein. (404 aa) |
| | AFA72944.1 | YkuD domain-containing protein. (402 aa) |
| | AFA72981.1 | YkuD domain-containing protein. (229 aa) |
| | uppP1 | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (295 aa) |
| | ndk | Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (138 aa) |
| | coaD | Phosphopantetheine adenylyltransferase CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (162 aa) |
| | AFA73027.1 | Putative RNA-binding protein; Belongs to the UPF0109 family. (80 aa) |
| | pyrH | Uridylate kinase PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa) |
| | AFA73072.1 | Putative acetyltransferase, GNAT family. (165 aa) |
| | ribF | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. (322 aa) |
| | thyA | Thymidylate synthase ThyA; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (277 aa) |
| | AFA73115.1 | Hypothetical protein. (338 aa) |
| | AFA73119.1 | Putative glycosyltransferase. (426 aa) |
| | AFA73120.1 | Putative HAD-superfamily hydrolase, subfamily IIB. (254 aa) |
| | thyX | Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (250 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (162 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (663 aa) |
| | AFA73226.1 | Putative acyltransferase. (311 aa) |
| | pimA | GDP-mannose-dependent alpha-(1-2)-phosphatidylinositol mannosyltransferase PimA. (374 aa) |
| | AFA73236.1 | Hypothetical protein. (206 aa) |
| | apt | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (195 aa) |
| | relA | GTP pyrophosphokinase RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (801 aa) |
| | mltG | YceG family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (458 aa) |
| | pyrB | Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (316 aa) |
| | pyrC | Dihydroorotase PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (436 aa) |
| | AFA73277.1 | Hypothetical protein. (206 aa) |
| | carA | Carbamoyl-phosphate synthase small chain CarA; Belongs to the CarA family. (389 aa) |
| | carB | Carbamoyl-phosphate synthase large chain CarB; Belongs to the CarB family. (1116 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase PyrF; Belongs to the OMP decarboxylase family. Type 2 subfamily. (273 aa) |
| | coaBC | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (432 aa) |
| | AFA73318.1 | Phosphoribosyltransferase. (173 aa) |
| | AFA73342.1 | Putative glycosyltransferase. (286 aa) |
| | AFA73348.1 | Putative glycosyltransferase. (290 aa) |
| | pyrD | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (367 aa) |
| | uppP2 | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (280 aa) |
| | mshC | L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase MshC; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (413 aa) |
| | AFA73413.1 | Putative membrane protein. (490 aa) |
| | AFA73455.1 | Putative glyoxalase/bleomycin resistance protein. (284 aa) |
| | AFA73576.1 | Putative NAD dependent epimerase/dehydratase. (307 aa) |
| | pyrG | CTP synthase PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (561 aa) |
| | coaE | dephospho-CoA kinase CoaE; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (298 aa) |
| | AFA73705.1 | Hypothetical protein. (492 aa) |
| | AFA73744.1 | Hypothetical protein. (508 aa) |
| | AFA73757.1 | Acyltransferase 3. (730 aa) |
| | murC | UDP-N-acetylmuramate--L-alanine ligase MurC; Cell wall formation; Belongs to the MurCDEF family. (544 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (405 aa) |
| | ftsW | Cell division protein FtsW; Belongs to the SEDS family. (629 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase MurD; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (540 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase MraY; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (365 aa) |
| | murF1 | UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase MurF. (198 aa) |
| | murE | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase MurE; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (497 aa) |
| | pimB | GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase PimB. (375 aa) |
| | AFA73896.1 | Hypothetical protein. (294 aa) |
| | oatA | O-acetyltransferase OatA. (974 aa) |
| | AFA73898.1 | Hypothetical protein. (294 aa) |
| | gpsA2 | Glycerol-3-phosphate dehydrogenase [NAD(P)+] 2; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (337 aa) |
| | nrdF2 | Ribonucleoside-diphosphate reductase subunit beta NrdF2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (336 aa) |
| | manA | Mannose-6-phosphate isomerase ManA. (415 aa) |
| | fbiC1 | FO synthase subunit 1. (409 aa) |
| | mshB | 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D- gluc opyranosidedeacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. (302 aa) |
| | lpqW | Monoacyl phosphatidylinositol tetramannoside-binding protein LpqW. (628 aa) |
| | AFA74200.1 | Hypothetical protein. (293 aa) |
| | purA1 | Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (466 aa) |
| | AFA74352.1 | propionate-CoA ligase protein. (637 aa) |
| | AFA74460.1 | Putative NUDIX hydrolase. (160 aa) |
| | tmk | Thymidylate kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (219 aa) |
| | adk | Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (184 aa) |
| | AFA74595.1 | LmbE-like protein. (225 aa) |
| | AFA74681.1 | Putative secreted esterase. (323 aa) |
| | AFA74712.1 | Putative NAD-dependent epimerase/dehydratase. (346 aa) |
| | AFA74741.1 | Putative glycosyltransferase. (435 aa) |
| | AFA74763.1 | Putative membrane protein. (340 aa) |
| | mshD | Mycothiol acetyltransferase MshD; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. (311 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase PurM. (373 aa) |
| | purF | Amidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (527 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (763 aa) |
| | AFA75187.1 | Putative acyl--CoA ligase. (578 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (227 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, PurS subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is th [...] (79 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Belongs to the SAICAR synthetase family. (295 aa) |
| | purB | Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (475 aa) |
| | purD | Phosphoribosylamine--glycine ligase PurD; Belongs to the GARS family. (417 aa) |
| | AFA75225.1 | Putative integral membrane protein. (728 aa) |
| | AFA75243.1 | Putative secreted esterase. (322 aa) |
| | AFA75299.1 | Putative glycosyltransferase. (414 aa) |
| | coaX | Type III pantothenate kinase CoaX; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (266 aa) |
| | hpt | Hypoxanthine-guanine phosphoribosyltransferase Hpt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (189 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (546 aa) |
| | AFA75368.1 | Putative adenylate cyclase. (523 aa) |
| | purA2 | Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa) |
| | pyrE | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (186 aa) |
| | AFA75398.1 | Putative secreted protein. (345 aa) |
| | AFA75493.1 | Putative membrane-bound calcineurin-like phosphoesterase. (381 aa) |
| | ugd2 | UDP-glucose 6-dehydrogenase Ugd. (478 aa) |
| | dcd | Deoxycytidine triphosphate deaminase Dcd; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (191 aa) |
| | AFA75641.1 | Putative oxidoreductase. (301 aa) |
| | pimC | Putative mannosyltransferase PimC. (383 aa) |
| | AFA75684.1 | AIR synthase-like protein. (485 aa) |
| | AFA75686.1 | Putative glycosyltransferase. (364 aa) |
| | AFA75697.1 | Putative UDP-N-acetylmuramyl tripeptide synthase; Mur ligase. (430 aa) |
| | AFA75698.1 | CobB/CobQ domain-containing protein. (239 aa) |
| | AFA75701.1 | Hypothetical protein. (185 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (422 aa) |
| | murF2 | UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D- alanine ligase MurF; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (439 aa) |
| | ddl | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (358 aa) |
| | AFA75774.1 | Putative acyltransferase. (381 aa) |
| | AFA75871.1 | Hypothetical protein. (274 aa) |
| | AFA75935.1 | Hypothetical protein. (398 aa) |
| | AFA75989.1 | Putative NAD dependent epimerase/dehydratase. (350 aa) |
| | AFA75996.1 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. (225 aa) |
