STRINGSTRING
AFA71290.1 AFA71290.1 AFA71140.1 AFA71140.1 AFA71135.1 AFA71135.1 AFA71163.1 AFA71163.1 AFA71296.1 AFA71296.1 AFA71303.1 AFA71303.1 AFA71340.1 AFA71340.1 AFA71417.1 AFA71417.1 thiE thiE thiS thiS thiG thiG AFA71799.1 AFA71799.1 AFA71835.1 AFA71835.1 AFA71837.1 AFA71837.1 AFA71849.1 AFA71849.1 thiD thiD thiC thiC AFA71927.1 AFA71927.1 AFA71962.1 AFA71962.1 AFA72065.1 AFA72065.1 AFA72082.1 AFA72082.1 AFA72435.1 AFA72435.1 glpX glpX AFA72657.1 AFA72657.1 glpK glpK AFA72759.1 AFA72759.1 AFA72870.1 AFA72870.1 AFA72933.1 AFA72933.1 AFA72983.1 AFA72983.1 AFA73095.1 AFA73095.1 suhB1 suhB1 dxs dxs pdxS pdxS pdxT pdxT AFA73248.1 AFA73248.1 pdxK pdxK cyp109 cyp109 AFA73562.1 AFA73562.1 ntaB ntaB AFA73572.1 AFA73572.1 AFA73594.1 AFA73594.1 AFA73623.1 AFA73623.1 pcaH pcaH pcaB pcaB suhB2 suhB2 AFA73855.1 AFA73855.1 wSD1 wSD1 uppS2 uppS2 AFA73983.1 AFA73983.1 yloV yloV thiL thiL AFA74016.1 AFA74016.1 AFA74084.1 AFA74084.1 AFA74134.1 AFA74134.1 AFA74135.1 AFA74135.1 AFA74189.1 AFA74189.1 AFA74323.1 AFA74323.1 mphP2 mphP2 AFA74403.1 AFA74403.1 AFA74406.1 AFA74406.1 AFA74424.1 AFA74424.1 AFA74471.1 AFA74471.1 AFA74474.1 AFA74474.1 iolG1 iolG1 AFA74479.1 AFA74479.1 AFA74482.1 AFA74482.1 AFA74485.1 AFA74485.1 AFA74486.1 AFA74486.1 iolG2 iolG2 AFA74493.1 AFA74493.1 AFA74528.1 AFA74528.1 aroE2 aroE2 AFA74659.1 AFA74659.1 AFA74664.1 AFA74664.1 AFA74675.1 AFA74675.1 cyp cyp AFA74720.1 AFA74720.1 AFA74796.1 AFA74796.1 AFA74798.1 AFA74798.1 AFA74802.1 AFA74802.1 AFA74831.1 AFA74831.1 AFA74861.1 AFA74861.1 AFA74865.1 AFA74865.1 catA catA pdxH pdxH serC serC AFA74987.1 AFA74987.1 wSD2 wSD2 cysQ cysQ AFA75110.1 AFA75110.1 hsaB hsaB kshA1 kshA1 kshA2 kshA2 AFA75133.1 AFA75133.1 AFA75140.1 AFA75140.1 AFA75141.1 AFA75141.1 AFA75154.1 AFA75154.1 AFA75156.1 AFA75156.1 AFA75157.1 AFA75157.1 AFA75158.1 AFA75158.1 AFA75159.1 AFA75159.1 AFA75171.1 AFA75171.1 AFA75270.1 AFA75270.1 AFA75271.1 AFA75271.1 AFA75276.1 AFA75276.1 AFA75278.1 AFA75278.1 AFA75280.1 AFA75280.1 AFA75285.1 AFA75285.1 AFA75286.1 AFA75286.1 AFA75287.1 AFA75287.1 AFA75289.1 AFA75289.1 AFA75303.1 AFA75303.1 AFA75306.1 AFA75306.1 AFA75307.1 AFA75307.1 AFA75308.1 AFA75308.1 AFA75309.1 AFA75309.1 AFA75322.1 AFA75322.1 AFA75327.1 AFA75327.1 AFA75355.1 AFA75355.1 AFA75405.1 AFA75405.1 AFA75495.1 AFA75495.1 AFA75501.1 AFA75501.1 AFA75513.1 AFA75513.1 AFA75525.1 AFA75525.1 AFA75550.1 AFA75550.1 AFA75551.1 AFA75551.1 AFA75554.1 AFA75554.1 eutC eutC AFA75617.1 AFA75617.1 wSD3 wSD3 AFA75670.1 AFA75670.1 AFA75671.1 AFA75671.1 AFA75675.1 AFA75675.1 AFA75854.1 AFA75854.1 AFA75894.1 AFA75894.1 AFA75895.1 AFA75895.1 AFA75917.1 AFA75917.1 AFA76005.1 AFA76005.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AFA71290.1Flavin reductase like domain-containing protein. (161 aa)
AFA71140.1Cytochrome P450. (399 aa)
AFA71135.1Putative ferredoxin oxidoreductase. (356 aa)
AFA71163.1Protein of unknown function DUF35. (147 aa)
AFA71296.1Cytochrome P450 monooxygenase. (397 aa)
AFA71303.1Cytochrome P450. (466 aa)
AFA71340.1Beta-lactamase domain-containing protein. (208 aa)
AFA71417.1Rhodanese-like domain-containing protein. (110 aa)
thiEThiamine-phosphate pyrophosphorylase ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). (177 aa)
thiSThiamine biosynthesis protein ThiS. (65 aa)
thiGThiazole synthase ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (259 aa)
AFA71799.1Beta-lactamase-like protein. (264 aa)
AFA71835.1NMT1/THI5-like protein. (367 aa)
AFA71837.1Hypothetical protein. (146 aa)
AFA71849.1Pterin-4a-carbinolamine dehydratase-like protein. (224 aa)
thiDPhosphomethylpyrimidine kinase ThiD. (290 aa)
thiCPhosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (563 aa)
AFA71927.1acyl-CoA dehydrogenase domain-containing protein. (399 aa)
AFA71962.1Putative NADPH-flavin oxidoreductase. (157 aa)
AFA72065.1Dihydroxyacetone kinase-like protein. (383 aa)
AFA72082.1Cytochrome P450. (418 aa)
AFA72435.1Putative vanillate O-demethylase oxygenase subunit A. (375 aa)
glpXFructose-1,6-bisphosphatase, class II. (331 aa)
AFA72657.1Putative cholesterol oxidase. (588 aa)
glpKGlycerol kinase GlpK; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (502 aa)
AFA72759.1Putative phenol hydroxylase, reductase component. (195 aa)
AFA72870.1Putative N,N'-dimethyl-4-nitrosoaniline-dependent alcohol oxidoreductase. (430 aa)
AFA72933.1Hypothetical protein. (109 aa)
AFA72983.1Cytochrome P450 monooxygenase. (487 aa)
AFA73095.1Putative phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (221 aa)
suhB1Inositol monophosphate phosphatase SuhB; Belongs to the inositol monophosphatase superfamily. (312 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (663 aa)
pdxSPyridoxal biosynthesis lyase PdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (282 aa)
pdxTGlutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (203 aa)
AFA73248.1Putative Zn-dependent hydrolase. (243 aa)
pdxKPyridoxine kinase PdxK. (263 aa)
cyp109Cytochrome P450 109. (396 aa)
AFA73562.1AMP-dependent synthetase and ligase. (480 aa)
ntaBNitrilotriacetate monooxygenase component B. (163 aa)
AFA73572.1Hypothetical protein. (136 aa)
AFA73594.1Glyoxalase/bleomycin resistance protein/dioxygenase. (127 aa)
AFA73623.1HAD-superfamily hydrolase, subfamily IIA. (673 aa)
pcaHProtocatechuate 3,4-dioxygenase beta chain PcaH. (260 aa)
pcaB3-carboxy-cis,cis-muconate cycloisomerase PcaB. (401 aa)
suhB2Inositol monophosphate phosphatase SuhB. (283 aa)
AFA73855.1Sugar nucleotide epimerase. (295 aa)
wSD1O-acyltransferase WSD. (474 aa)
uppS2Undecaprenyl pyrophosphate synthase 2; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (273 aa)
AFA73983.1DegV domain-containing protein. (287 aa)
yloVDAK2 domain-containing protein YloV. (594 aa)
thiLThiamine-monophosphate kinase ThiL; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (377 aa)
AFA74016.15-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase. (257 aa)
AFA74084.1Putative NUDIX hydrolase. (280 aa)
AFA74134.1Putative cysteine dioxygenase type I. (209 aa)
AFA74135.1Hypothetical protein. (124 aa)
AFA74189.1acyl-CoA oxidase/dehydrogenase. (413 aa)
AFA74323.1Histidinol-phosphate phosphatase. (267 aa)
mphP2Phenol hydroxylase P5 protein MphP. (645 aa)
AFA74403.1Putative amidohydrolase. (305 aa)
AFA74406.1Flavin reductase like domain-containing protein. (175 aa)
AFA74424.1Putative FAD dependent oxidoreductase. (456 aa)
AFA74471.1Putative oxidoreductase. (328 aa)
AFA74474.1Putative oxidoreductase. (397 aa)
iolG1Inositol 2-dehydrogenase 2. (335 aa)
AFA74479.1Oxidoreductase domain-containing protein. (344 aa)
AFA74482.1Putative oxidoreductase. (408 aa)
AFA74485.1Putative 5-deoxy-glucuronate isomerase. (287 aa)
AFA74486.1Putative 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Belongs to the TPP enzyme family. (680 aa)
iolG2Inositol 2-dehydrogenase IolG; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). (352 aa)
AFA74493.1Putative oxidoreductase. (342 aa)
AFA74528.1Putative 4-hydroxyphenylpyruvate dioxygenase. (656 aa)
aroE2Shikimate dehydrogenase AroE; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (312 aa)
AFA74659.1Putative FMN-dependent alpha-hydroxy acid dehydrogenase. (385 aa)
AFA74664.1Putative ferredoxin oxidoreductase. (356 aa)
AFA74675.1Cytochrome P450. (460 aa)
cypLanosterol 14-alpha demethylase Cyp; Belongs to the cytochrome P450 family. (453 aa)
AFA74720.1Cytochrome P450 monooxygenase. (411 aa)
AFA74796.1FAD-binding oxidoreductase. (467 aa)
AFA74798.1Putative cytochrome P450. (404 aa)
AFA74802.1Putative cytochrome P450. (418 aa)
AFA74831.1Putative N,N'-dimethyl-4-nitrosoaniline-dependent alcohol oxidoreductase. (423 aa)
AFA74861.1Inositol monophosphatase family protein. (247 aa)
AFA74865.1Putative cholesterol oxidase. (565 aa)
catACatechol 1,2-dioxygenase CatA. (291 aa)
pdxHPyridoxine/pyridoxamine 5'-phosphate oxidase PdxH; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (249 aa)
serCPhosphoserine aminotransferase SerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (380 aa)
AFA74987.1Flavin reductase like domain-containing protein. (192 aa)
wSD2O-acyltransferase WSD; Belongs to the long-chain O-acyltransferase family. (467 aa)
cysQPutative 3'-phosphoadenosine 5'-phosphate phosphatase CysQ. (253 aa)
AFA75110.1Putative diacylglycerol O-acyltransferase. (489 aa)
hsaBFlavin-dependent monooxygenase, reductase subunit HsaB. (191 aa)
kshA13-ketosteroid-9-alpha-hydroxylase, oxygenase subunit KshA. (404 aa)
kshA23-ketosteroid-9-alpha-hydroxylase, oxygenase subunit KshA. (398 aa)
AFA75133.1Putative FMN-dependent oxidoreductase. (170 aa)
AFA75140.1Putative ferredoxin oxidoreductase. (354 aa)
AFA75141.1Putative acyl-CoA dehydrogenase. (386 aa)
AFA75154.1Putative fatty-acid--CoA ligase. (564 aa)
AFA75156.1Putative MaoC-like dehydratase. (147 aa)
AFA75157.1Hypothetical protein. (336 aa)
AFA75158.1Putative acyl-CoA dehydrogenase. (387 aa)
AFA75159.1Putative acyl-CoA dehydrogenase. (356 aa)
AFA75171.1Putative phenylacetate-CoA oxygenase/reductase, PaaK subunit. (368 aa)
AFA75270.1Putative acyl-CoA dehydrogenase. (405 aa)
AFA75271.1Putative acyl-CoA dehydrogenase. (382 aa)
AFA75276.1Putative fatty-acid--CoA ligase. (486 aa)
AFA75278.1Putative bifunctional P-450/NADPH-P450 reductase; Belongs to the cytochrome P450 family. (484 aa)
AFA75280.1Hypothetical protein. (329 aa)
AFA75285.1Cytochrome P450 monooxygenase. (435 aa)
AFA75286.1acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
AFA75287.1Deazaflavin-dependent nitroreductase family protein. (161 aa)
AFA75289.1Cytochrome P450 monooxygenase. (421 aa)
AFA75303.1Hypothetical protein. (123 aa)
AFA75306.1Putative enoyl-CoA hydratase. (256 aa)
AFA75307.1Putative CoA-transferase, subunit alpha. (309 aa)
AFA75308.1Putative CoA-transferase, subunit beta. (252 aa)
AFA75309.1Putative oxidoreductase, 2-nitropropane dioxygenase family. (376 aa)
AFA75322.1Putative oxidoreductase, short-chain dehydrogenase/reductase family. (273 aa)
AFA75327.1Hypothetical protein. (139 aa)
AFA75355.1Rhodanese-like protein. (137 aa)
AFA75405.1Putative FAD-dependent oxidoreductase. (995 aa)
AFA75495.1Flavin reductase-like domain-containing protein. (167 aa)
AFA75501.1Putative cytochrome P450, ferredoxin-domain containing. (819 aa)
AFA75513.1Putative mannitol 2-dehydrogenase. (493 aa)
AFA75525.1Putative cytochrome P450. (408 aa)
AFA75550.1FAD-dependent oxidoreductase. (461 aa)
AFA75551.1Deazaflavin-dependent nitroreductase family protein. (142 aa)
AFA75554.1Putative amidohydrolase. (377 aa)
eutCEthanolamine ammonia-lyase, light chain EutC; Belongs to the EutC family. (258 aa)
AFA75617.1Rieske (2Fe-2S) domain-containing protein. (356 aa)
wSD3O-acyltransferase WSD; Belongs to the long-chain O-acyltransferase family. (473 aa)
AFA75670.1Hypothetical protein, DUF162. (209 aa)
AFA75671.1Putative iron-sulfur protein. (497 aa)
AFA75675.1Putative secreted ceramidase. (690 aa)
AFA75854.1Hypothetical protein. (139 aa)
AFA75894.1Putative monooxygenase. (508 aa)
AFA75895.1Cytochrome P450. (422 aa)
AFA75917.1Inositol-3-phosphate synthase. (338 aa)
AFA76005.1Fatty acid hydroxylase. (364 aa)
Your Current Organism:
Gordonia polyisoprenivorans
NCBI taxonomy Id: 1112204
Other names: G. polyisoprenivorans VH2, Gordonia polyisoprenivorans VH2, Gordonia polyisoprenivorans str. VH2, Gordonia polyisoprenivorans strain VH2
Server load: low (14%) [HD]