STRINGSTRING
pyrE pyrE prs prs upp upp apt apt pyrR pyrR AFA73318.1 AFA73318.1 AFA73506.1 AFA73506.1 AFA74506.1 AFA74506.1 purF purF AFA75227.1 AFA75227.1 hpt hpt AFA75760.1 AFA75760.1 AFA75935.1 AFA75935.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pyrEOrotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (186 aa)
prsRibose-phosphate pyrophosphokinase Prs; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)
uppUracil phosphoribosyltransferase Upp; Belongs to the UPRTase family. (207 aa)
aptAdenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (195 aa)
pyrRBifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (195 aa)
AFA73318.1Phosphoribosyltransferase. (173 aa)
AFA73506.1Phosphoribosyl transferase. (230 aa)
AFA74506.1Hypothetical protein. (226 aa)
purFAmidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (527 aa)
AFA75227.1Putative ATP-dependent DNA helicase. (704 aa)
hptHypoxanthine-guanine phosphoribosyltransferase Hpt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (189 aa)
AFA75760.1Hypothetical protein. (186 aa)
AFA75935.1Hypothetical protein. (398 aa)
Your Current Organism:
Gordonia polyisoprenivorans
NCBI taxonomy Id: 1112204
Other names: G. polyisoprenivorans VH2, Gordonia polyisoprenivorans VH2, Gordonia polyisoprenivorans str. VH2, Gordonia polyisoprenivorans strain VH2
Server load: low (30%) [HD]