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surE | Multifunctional protein SurE. (259 aa) | ||||
AFA71623.1 | Ribonucleotide reductase small subunit-like protein. (323 aa) | ||||
AFA71946.1 | Carbon-nitrogen hydrolase family protein. (282 aa) | ||||
hyuA | D-hydantoinase HyuA. (473 aa) | ||||
cdd | Cytidine deaminase Cdd. (139 aa) | ||||
deoA | Thymidine phosphorylase DeoA. (448 aa) | ||||
upp | Uracil phosphoribosyltransferase Upp; Belongs to the UPRTase family. (207 aa) | ||||
punA | Purine nucleoside phosphorylase PunA; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (267 aa) | ||||
ndk | Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (138 aa) | ||||
pyrH | Uridylate kinase PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa) | ||||
thyA | Thymidylate synthase ThyA; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (277 aa) | ||||
thyX | Thymidylate synthase ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (250 aa) | ||||
dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (162 aa) | ||||
pyrR | Bifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (195 aa) | ||||
pyrB | Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (316 aa) | ||||
pyrC | Dihydroorotase PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (436 aa) | ||||
carA | Carbamoyl-phosphate synthase small chain CarA; Belongs to the CarA family. (389 aa) | ||||
carB | Carbamoyl-phosphate synthase large chain CarB; Belongs to the CarB family. (1116 aa) | ||||
pyrF | Orotidine 5'-phosphate decarboxylase PyrF; Belongs to the OMP decarboxylase family. Type 2 subfamily. (273 aa) | ||||
pyrD | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (367 aa) | ||||
cmk | Cytidylate kinase Cmk. (227 aa) | ||||
pyrG | CTP synthase PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (561 aa) | ||||
nrdF2 | Ribonucleoside-diphosphate reductase subunit beta NrdF2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (336 aa) | ||||
nrdE | Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (735 aa) | ||||
tmk | Thymidylate kinase Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (219 aa) | ||||
pyrE | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (186 aa) | ||||
dcd | Deoxycytidine triphosphate deaminase Dcd; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (191 aa) | ||||
AFA75666.1 | Putative cytosine deaminase. (167 aa) | ||||
AFA75680.1 | Carbon-nitrogen hydrolase family protein. (296 aa) |