18 items (Glarea lozoyensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GLAREA_08178	Nucleic acid-binding protein. (283 aa)
	GLAREA_12665	P-loop containing nucleoside triphosphate hydrolase. (471 aa)
	GLAREA_01548	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (695 aa)
	GLAREA_07631	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (351 aa)
	GLAREA_07000	BRCT. (1171 aa)
	GLAREA_10934	BRCT. (1074 aa)
	GLAREA_00159	P-loop containing nucleoside triphosphate hydrolase. (1643 aa)
	GLAREA_10118	RMI1_N domain-containing protein. (238 aa)
	GLAREA_10393	P-loop containing nucleoside triphosphate hydrolase; Belongs to the RecA family. (336 aa)
	GLAREA_11294	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2944 aa)
	GLAREA_08933	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (665 aa)
	GLAREA_02827	Protein kinase-like (PK-like); Belongs to the PI3/PI4-kinase family. (2457 aa)
	GLAREA_10596	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (609 aa)
	GLAREA_00728	BRCT. (1303 aa)
	GLAREA_10837	P-loop containing nucleoside triphosphate hydrolase. (1335 aa)
	GLAREA_07471	Ribonuclease H-like protein. (661 aa)
	GLAREA_08756	P-loop containing nucleoside triphosphate hydrolase. (470 aa)
	GLAREA_08951	DsRNA-binding protein. (730 aa)

Your Current Organism:

Glarea lozoyensis

NCBI taxonomy Id: 1116229
Other names: G. lozoyensis ATCC 20868, Glarea lozoyensis ATCC 20868

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GLAREA_00159	GLAREA_00728	S3DAJ8	S3DT07	P-loop containing nucleoside triphosphate hydrolase.	BRCT.	0.875
GLAREA_00159	GLAREA_01548	S3DAJ8	S3D0S8	P-loop containing nucleoside triphosphate hydrolase.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.892
GLAREA_00159	GLAREA_02827	S3DAJ8	S3DK46	P-loop containing nucleoside triphosphate hydrolase.	Protein kinase-like (PK-like); Belongs to the PI3/PI4-kinase family.	0.872
GLAREA_00159	GLAREA_07000	S3DAJ8	S3D682	P-loop containing nucleoside triphosphate hydrolase.	BRCT.	0.648
GLAREA_00159	GLAREA_07471	S3DAJ8	S3E1J0	P-loop containing nucleoside triphosphate hydrolase.	Ribonuclease H-like protein.	0.988
GLAREA_00159	GLAREA_07631	S3DAJ8	S3D1R6	P-loop containing nucleoside triphosphate hydrolase.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.876
GLAREA_00159	GLAREA_08178	S3DAJ8	S3CWZ3	P-loop containing nucleoside triphosphate hydrolase.	Nucleic acid-binding protein.	0.901
GLAREA_00159	GLAREA_08756	S3DAJ8	S3EEA8	P-loop containing nucleoside triphosphate hydrolase.	P-loop containing nucleoside triphosphate hydrolase.	0.888
GLAREA_00159	GLAREA_08933	S3DAJ8	S3DGG8	P-loop containing nucleoside triphosphate hydrolase.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.870
GLAREA_00159	GLAREA_08951	S3DAJ8	S3EF47	P-loop containing nucleoside triphosphate hydrolase.	DsRNA-binding protein.	0.895
GLAREA_00159	GLAREA_10118	S3DAJ8	S3DBD9	P-loop containing nucleoside triphosphate hydrolase.	RMI1_N domain-containing protein.	0.860
GLAREA_00159	GLAREA_10393	S3DAJ8	S3DC79	P-loop containing nucleoside triphosphate hydrolase.	P-loop containing nucleoside triphosphate hydrolase; Belongs to the RecA family.	0.800
GLAREA_00159	GLAREA_10596	S3DAJ8	S3DSG4	P-loop containing nucleoside triphosphate hydrolase.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.991
GLAREA_00159	GLAREA_10837	S3DAJ8	S3DT49	P-loop containing nucleoside triphosphate hydrolase.	P-loop containing nucleoside triphosphate hydrolase.	0.728
GLAREA_00159	GLAREA_10934	S3DAJ8	S3D9U9	P-loop containing nucleoside triphosphate hydrolase.	BRCT.	0.772
GLAREA_00159	GLAREA_11294	S3DAJ8	S3DEQ5	P-loop containing nucleoside triphosphate hydrolase.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.910
GLAREA_00159	GLAREA_12665	S3DAJ8	S3CYM3	P-loop containing nucleoside triphosphate hydrolase.	P-loop containing nucleoside triphosphate hydrolase.	0.663
GLAREA_00728	GLAREA_00159	S3DT07	S3DAJ8	BRCT.	P-loop containing nucleoside triphosphate hydrolase.	0.875
GLAREA_00728	GLAREA_01548	S3DT07	S3D0S8	BRCT.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.730
GLAREA_00728	GLAREA_02827	S3DT07	S3DK46	BRCT.	Protein kinase-like (PK-like); Belongs to the PI3/PI4-kinase family.	0.982