STRINGSTRING
GLAREA_04009 GLAREA_04009 GLAREA_09490 GLAREA_09490 GLAREA_04978 GLAREA_04978 GLAREA_01702 GLAREA_01702 GLAREA_08156 GLAREA_08156 GLAREA_10245 GLAREA_10245 GLAREA_05357 GLAREA_05357 GLAREA_11294 GLAREA_11294 GLAREA_10244 GLAREA_10244 GLAREA_04977 GLAREA_04977 GLAREA_07090 GLAREA_07090 GLAREA_05909 GLAREA_05909 GLAREA_01703 GLAREA_01703 GLAREA_11959 GLAREA_11959
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLAREA_04009Histone H2A; Belongs to the histone H2A family. (142 aa)
GLAREA_09490Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (158 aa)
GLAREA_04978Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (127 aa)
GLAREA_01702Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
GLAREA_08156Histone-fold containing protein. (544 aa)
GLAREA_10245Histone H2B; Belongs to the histone H2B family. (136 aa)
GLAREA_05357Winged helix DNA-binding protein. (209 aa)
GLAREA_11294Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2944 aa)
GLAREA_10244Histone H2A; Belongs to the histone H2A family. (134 aa)
GLAREA_04977Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1003 aa)
GLAREA_07090Histone-fold containing protein. (146 aa)
GLAREA_05909Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1282 aa)
GLAREA_01703Histone H3; Belongs to the histone H3 family. (136 aa)
GLAREA_11959FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (574 aa)
Your Current Organism:
Glarea lozoyensis
NCBI taxonomy Id: 1116229
Other names: G. lozoyensis ATCC 20868, Glarea lozoyensis ATCC 20868
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