STRINGSTRING
GLAREA_08146 GLAREA_08146 GLAREA_01994 GLAREA_01994 GLAREA_01577 GLAREA_01577 GLAREA_02756 GLAREA_02756 GLAREA_02036 GLAREA_02036 GLAREA_02602 GLAREA_02602 GLAREA_04803 GLAREA_04803 GLAREA_09653 GLAREA_09653 GLAREA_09680 GLAREA_09680 GLAREA_00740 GLAREA_00740 GLAREA_00197 GLAREA_00197 GLAREA_00267 GLAREA_00267 GLAREA_00709 GLAREA_00709 GLAREA_12605 GLAREA_12605 GLAREA_03837 GLAREA_03837 GLAREA_03496 GLAREA_03496 GLAREA_01378 GLAREA_01378 GLAREA_01888 GLAREA_01888 GLAREA_07070 GLAREA_07070 GLAREA_06943 GLAREA_06943 gloH gloH gloI gloI GLAREA_00731 GLAREA_00731 GLAREA_09040 GLAREA_09040 GLAREA_02306 GLAREA_02306 GLAREA_07760 GLAREA_07760 GLAREA_04659 GLAREA_04659 GLAREA_04844 GLAREA_04844 GLAREA_09854 GLAREA_09854 gloG gloG GLAREA_10812 GLAREA_10812 GLAREA_11225 GLAREA_11225 GLAREA_01173 GLAREA_01173 GLAREA_08959 GLAREA_08959 GLAREA_10192 GLAREA_10192 GLAREA_10568 GLAREA_10568
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLAREA_08146NAD(P)-binding Rossmann-fold containing protein. (365 aa)
GLAREA_019943-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (776 aa)
GLAREA_01577Citrate synthase; Belongs to the citrate synthase family. (475 aa)
GLAREA_02756Acetolactate synthase. (698 aa)
GLAREA_02036Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. Belongs to the acetyltransferase family. (667 aa)
GLAREA_02602Carbamate kinase-like protein; In the N-terminal section; belongs to the acetylglutamate kinase family. (895 aa)
GLAREA_04803Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate; Belongs to the ArgJ family. (474 aa)
GLAREA_09653Aspartate aminotransferase. (421 aa)
GLAREA_09680Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (413 aa)
GLAREA_00740Zn-dependent exopeptidase. (377 aa)
GLAREA_00197Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (414 aa)
GLAREA_00267D-aminoacid aminotransferase-like PLP-dependent enzyme. (376 aa)
GLAREA_00709IlvD/EDD N-terminal. (606 aa)
GLAREA_12605Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
GLAREA_03837Citrate synthase; Belongs to the citrate synthase family. (473 aa)
GLAREA_03496PLP-dependent transferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (490 aa)
GLAREA_01378PLP-dependent transferase. (487 aa)
GLAREA_01888Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (793 aa)
GLAREA_07070Aspartokinase. (530 aa)
GLAREA_06943Isocitrate/Isopropylmalate dehydrogenase-like protein. (357 aa)
gloHIsopropyl malate synthase gloH; 2-isopropylmalate synthase; part of the gene cluster that mediates the biosynthesis of pneumocandins, lipohexapeptides of the echinocandin family that prevent fungal cell wall formation by non- competitive inhibition of beta-1,3-glucan synthase. The 10,12-dimethylmyristoyl side chain is synthesized by the reducing polyketide synthase gloL/GLPKS4. The thioesterase gloN/GLHYD exclusively interacts with gloL/GLPKS4 to maintain turnover of the polyketide side chain. The 10R,12S- dimethylmyristic acid is then transferred to the first thiolation domain of the [...] (617 aa)
gloI3-isopropylmalate dehydrogenase gloI; 3-isopropylmalate dehydrogenase; part of the gene cluster that mediates the biosynthesis of pneumocandins, lipohexapeptides of the echinocandin family that prevent fungal cell wall formation by non- competitive inhibition of beta-1,3-glucan synthase. The 10,12-dimethylmyristoyl side chain is synthesized by the reducing polyketide synthase gloL/GLPKS4. The thioesterase gloN/GLHYD exclusively interacts with gloL/GLPKS4 to maintain turnover of the polyketide side chain. The 10R,12S- dimethylmyristic acid is then transferred to the first thiolation dom [...] (373 aa)
GLAREA_00731PLP-dependent transferase. (545 aa)
GLAREA_09040ACT-like protein. (320 aa)
GLAREA_02306Aldolase. (661 aa)
GLAREA_07760Aldolase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (493 aa)
GLAREA_04659Aspartate aminotransferase. (417 aa)
GLAREA_04844Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (377 aa)
GLAREA_09854IlvD/EDD N-terminal. (603 aa)
gloGBranched-chain amino acid aminotransferase gloG; Branched-chain amino acid aminotransferase; part of the gene cluster that mediates the biosynthesis of pneumocandins, lipohexapeptides of the echinocandin family that prevent fungal cell wall formation by non-competitive inhibition of beta-1,3-glucan synthase. The 10,12-dimethylmyristoyl side chain is synthesized by the reducing polyketide synthase gloL/GLPKS4. The thioesterase gloN/GLHYD exclusively interacts with gloL/GLPKS4 to maintain turnover of the polyketide side chain. The 10R,12S-dimethylmyristic acid is then transferred to the [...] (358 aa)
GLAREA_108123-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (367 aa)
GLAREA_11225Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (413 aa)
GLAREA_01173Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (799 aa)
GLAREA_08959Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (809 aa)
GLAREA_10192Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (428 aa)
GLAREA_10568Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (399 aa)
Your Current Organism:
Glarea lozoyensis
NCBI taxonomy Id: 1116229
Other names: G. lozoyensis ATCC 20868, Glarea lozoyensis ATCC 20868
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.