(33 nodes) Glutathione metabolism, and Glutathione S-transferase, N-terminal domain network (Sinorhizobium fredii HH103)

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experimentally determined

Predicted Interactions

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Your Input:
	gsh1	Glutamate-cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (457 aa)
	CCE94968.1	Conserved hypothetical protein. (142 aa)
	gst1	Gst1 protein; Glutathione S-transferase; Belongs to the GST superfamily. (235 aa)
	CCE94973.1	FAD-dependent oxidoreductase. (405 aa)
	gst3	Gst3 protein; Glutathione S-transferase. (216 aa)
	CCE95092.1	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (161 aa)
	gst5	Gst5 protein; Glutathione S-transferase; Belongs to the GST superfamily. (209 aa)
	gst9	Gst9 protein; Glutathione S-transferase. (160 aa)
	gst11	Structure of glutathione S-transferase III in apo form. (72 aa)
	pepN	PepN protein; Aminopeptidase N. (886 aa)
	CCE95238.1	Hypothetical protein. (57 aa)
	CCE95239.1	Hypothetical unknown transmembrane protein. (57 aa)
	gst7	Glutathione S-transferase family protein; Belongs to the GST superfamily. (233 aa)
	pepA	Leucine aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (497 aa)
	ureX	Hypothetical protein; Glutathione S-transferase. (203 aa)
	CCE96014.1	Putative BolA family protein; Belongs to the BolA/IbaG family. (77 aa)
	CCE96015.1	Conserved hypothetical protein. (81 aa)
	CCE96016.1	Putative glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. (111 aa)
	CCE96374.1	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 ChkSERCA3; SERCA3; Calcium pump 3; SR Ca(2+)-ATPase 3. (625 aa)
	gstA	GstA protein; Glutathione S-transferase. (202 aa)
	CCE96393.1	Glutathione S-transferase domain-containing protein. (318 aa)
	CCE96459.1	Glutathione S-transferase-like protein. (201 aa)
	CCE97025.1	Putative gamma-glutamyltranspeptidase. (546 aa)
	CCE97084.1	Uncharacterized protein conserved in bacteria. (142 aa)
	CCE97085.1	Carbon-nitrogen hydrolase family protein. (290 aa)
	grxC	Glutaredoxin-C6 Glutaredoxin-C2 homolog 1; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (85 aa)
	chaC	Cation transport regulator-like protein 2; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (188 aa)
	gst13	Gst13 protein; Glutathione S-transferase. (215 aa)
	CCE98139.1	CYTOSOL_AP domain-containing protein; Unnamed protein product; Belongs to the peptidase M17 family. (463 aa)
	CCE98368.1	Predicted glutathione S-transferase protein. (228 aa)
	gst4	Glutathione S-transferase family protein. (230 aa)
	gshB2	Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. (315 aa)
	CCE98428.1	Cation transport protein, ChaC related; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (236 aa)

Your Current Organism:

Sinorhizobium fredii HH103

NCBI taxonomy Id: 1117943
Other names: S. fredii HH103, Sinorhizobium fredii str. HH103, Sinorhizobium fredii strain HH103

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCE94973.1	gst1	SFHH103_00473	SFHH103_00472	FAD-dependent oxidoreductase.	Gst1 protein; Glutathione S-transferase; Belongs to the GST superfamily.	0.480
CCE95092.1	CCE96393.1	SFHH103_00592	SFHH103_01898	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Glutathione S-transferase domain-containing protein.	0.918
CCE95092.1	CCE96459.1	SFHH103_00592	SFHH103_01964	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Glutathione S-transferase-like protein.	0.901
CCE95092.1	CCE97025.1	SFHH103_00592	SFHH103_02530	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Putative gamma-glutamyltranspeptidase.	0.902
CCE95092.1	CCE98368.1	SFHH103_00592	SFHH103_03877	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Predicted glutathione S-transferase protein.	0.917
CCE95092.1	CCE98428.1	SFHH103_00592	SFHH103_03937	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Cation transport protein, ChaC related; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.900
CCE95092.1	chaC	SFHH103_00592	SFHH103_02630	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Cation transport regulator-like protein 2; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.900
CCE95092.1	gshB2	SFHH103_00592	SFHH103_03914	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.	0.910
CCE95092.1	gst13	SFHH103_00592	SFHH103_03294	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Gst13 protein; Glutathione S-transferase.	0.901
CCE95092.1	gst3	SFHH103_00592	SFHH103_00517	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Gst3 protein; Glutathione S-transferase.	0.901
CCE95092.1	gst4	SFHH103_00592	SFHH103_03898	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Glutathione S-transferase family protein.	0.901
CCE95092.1	gst5	SFHH103_00592	SFHH103_00648	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Gst5 protein; Glutathione S-transferase; Belongs to the GST superfamily.	0.901
CCE95092.1	gst9	SFHH103_00592	SFHH103_00652	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Gst9 protein; Glutathione S-transferase.	0.914
CCE95092.1	ureX	SFHH103_00592	SFHH103_00852	AhpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.	Hypothetical protein; Glutathione S-transferase.	0.901
CCE95238.1	CCE95239.1	SFHH103_00739	SFHH103_00740	Hypothetical protein.	Hypothetical unknown transmembrane protein.	0.767
CCE95238.1	gst7	SFHH103_00739	SFHH103_00741	Hypothetical protein.	Glutathione S-transferase family protein; Belongs to the GST superfamily.	0.502
CCE95239.1	CCE95238.1	SFHH103_00740	SFHH103_00739	Hypothetical unknown transmembrane protein.	Hypothetical protein.	0.767
CCE95239.1	gst7	SFHH103_00740	SFHH103_00741	Hypothetical unknown transmembrane protein.	Glutathione S-transferase family protein; Belongs to the GST superfamily.	0.509
CCE96014.1	CCE96015.1	SFHH103_01517	SFHH103_01518	Putative BolA family protein; Belongs to the BolA/IbaG family.	Conserved hypothetical protein.	0.781
CCE96014.1	CCE96016.1	SFHH103_01517	SFHH103_01519	Putative BolA family protein; Belongs to the BolA/IbaG family.	Putative glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily.	0.979