STRINGSTRING
B5G21_08885 B5G21_08885 B5G21_08745 B5G21_08745 B5G21_08750 B5G21_08750 B5G21_08760 B5G21_08760 ilvD ilvD B5G21_06790 B5G21_06790 B5G21_06795 B5G21_06795 ilvC ilvC B5G21_08365 B5G21_08365 leuA leuA leuC leuC leuD leuD leuB leuB B5G21_04250 B5G21_04250 ldh ldh B5G21_00280 B5G21_00280 B5G21_00145 B5G21_00145 pckA pckA B5G21_05435 B5G21_05435 B5G21_02765 B5G21_02765 B5G21_02635 B5G21_02635 B5G21_02620 B5G21_02620 B5G21_01685 B5G21_01685 B5G21_07500 B5G21_07500
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
B5G21_08885Unannotated protein; Belongs to the pyruvate kinase family. (489 aa)
B5G21_08745Unannotated protein. (698 aa)
B5G21_08750Unannotated protein. (83 aa)
B5G21_08760Unannotated protein; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (265 aa)
ilvDUnannotated protein; Belongs to the IlvD/Edd family. (554 aa)
B5G21_06790Unannotated protein. (678 aa)
B5G21_06795Unannotated protein. (157 aa)
ilvCUnannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (332 aa)
B5G21_08365Unannotated protein. (390 aa)
leuAUnannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (506 aa)
leuCUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (421 aa)
leuDUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. (166 aa)
leuBUnannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (388 aa)
B5G21_04250Unannotated protein. (375 aa)
ldhUnannotated protein; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (316 aa)
B5G21_00280Unannotated protein; Belongs to the PEP-utilizing enzyme family. (913 aa)
B5G21_00145Unannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (891 aa)
pckAUnannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (528 aa)
B5G21_05435Unannotated protein. (348 aa)
B5G21_02765Unannotated protein. (360 aa)
B5G21_02635Unannotated protein; Belongs to the pyruvate kinase family. (486 aa)
B5G21_02620Unannotated protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (930 aa)
B5G21_01685Unannotated protein. (546 aa)
B5G21_07500Unannotated protein. (471 aa)
Your Current Organism:
Enorma massiliensis
NCBI taxonomy Id: 1118060
Other names: Coriobacteriaceae bacterium phI, E. massiliensis phI, Enorma massiliensis phI
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