STRINGSTRING
B5M09_012306 B5M09_012306 KATNA1 KATNA1 B5M09_004415 B5M09_004415 H257_11233 H257_11233 B5M09_010872 B5M09_010872 B5M09_009230 B5M09_009230 B5M09_000893 B5M09_000893 KATNAL2 KATNAL2 B5M09_001181 B5M09_001181 H257_01414 H257_01414 H257_00935 H257_00935 H257_01267 H257_01267 H257_14049 H257_14049 H257_14565 H257_14565 H257_15295 H257_15295 DYB25_008069 DYB25_008069 H257_17381 H257_17381 H257_18759 H257_18759 H257_09144 H257_09144 B5M09_011430 B5M09_011430 B5M09_006627 B5M09_006627 H257_07378 H257_07378 B5M09_005176 B5M09_005176 B5M09_003342 B5M09_003342 H257_06671 H257_06671 H257_04624 H257_04624 H257_04112 H257_04112 H257_03817 H257_03817 DYB25_003992 DYB25_003992
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
B5M09_012306Dynein light chain. (96 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays. (559 aa)
B5M09_004415Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
H257_11233Spindle pole body component. (811 aa)
B5M09_010872Dynein light chain. (111 aa)
B5M09_009230Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (175 aa)
B5M09_000893Dynein light chain. (89 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (523 aa)
B5M09_001181Dynein light chain. (98 aa)
H257_01414Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (389 aa)
H257_00935Dynein light chain. (116 aa)
H257_01267Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (304 aa)
H257_14049Dynein light chain roadblock. (109 aa)
H257_14565Actin. (376 aa)
H257_15295F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (279 aa)
DYB25_008069Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
H257_17381Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes. Belongs to the WD repeat LIS1/nudF family. (425 aa)
H257_18759Spindle pole body component. (775 aa)
H257_09144Dynein light chain. (92 aa)
B5M09_011430Dynein light chain. (103 aa)
B5M09_006627Tubulin-specific chaperone A; Belongs to the TBCA family. (104 aa)
H257_07378Spindle pole body component. (972 aa)
B5M09_005176Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (121 aa)
B5M09_003342Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (170 aa)
H257_06671Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (433 aa)
H257_04624Katanin p80 WD40 repeat-containing subunit B1 homolog; May participate in a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays; Belongs to the WD repeat KATNB1 family. (604 aa)
H257_04112Dynein light chain roadblock. (101 aa)
H257_03817Uncharacterized protein. (388 aa)
DYB25_003992Dynein light chain. (103 aa)
Your Current Organism:
Aphanomyces astaci
NCBI taxonomy Id: 112090
Other names: A. astaci
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.