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topA | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (694 aa) | ||||
flgE2 | Flagellar hook protein FlgE. (846 aa) | ||||
rpmB | 50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (64 aa) | ||||
CCUN_0454 | Toprim domain-containing protein. (402 aa) | ||||
CCUN_0471 | DNA_rep/recomb_RecO_N domain-containing protein. (204 aa) | ||||
parB | Chromosome partitioning protein; Belongs to the ParB family. (280 aa) | ||||
fliL | Flagellar protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. (179 aa) | ||||
rpmG | 50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (52 aa) | ||||
rplK | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (141 aa) | ||||
rplA | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (233 aa) | ||||
rplJ | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (159 aa) | ||||
rplL | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (124 aa) | ||||
rpsL | 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (128 aa) | ||||
rpsG | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) | ||||
rplU | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa) | ||||
rpmA | 50S ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (84 aa) | ||||
recN | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (507 aa) | ||||
rpmH | 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (44 aa) | ||||
gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (769 aa) | ||||
flgH | Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (232 aa) | ||||
fliP | Flagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (246 aa) | ||||
rpsP | 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (75 aa) | ||||
rimM | Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (179 aa) | ||||
rplS | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (118 aa) | ||||
rpsA | 30S ribosomal protein S1. (556 aa) | ||||
flaC | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (249 aa) | ||||
flgG2 | Flagellar basal body protein. (270 aa) | ||||
flgG | Flagellar basal-body rod protein FlgG; Belongs to the flagella basal body rod proteins family. (263 aa) | ||||
flgL | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (762 aa) | ||||
rpsO | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (90 aa) | ||||
clpS | ATP-dependent Clp protease adapter protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. (97 aa) | ||||
recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (192 aa) | ||||
rpsT | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (87 aa) | ||||
rplI | 50S ribosomal protein L9; Binds to the 23S rRNA. (147 aa) | ||||
CCUN_1211 | Nucleoid-associated protein CCUN_1211; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (101 aa) | ||||
gyrA | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (855 aa) | ||||
flaB | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (603 aa) | ||||
dnaG-2 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (606 aa) | ||||
priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (610 aa) | ||||
CCUN_1434 | Putative flagellar protein FliJ. (145 aa) | ||||
rarA | Recombination factor protein RarA. (393 aa) | ||||
dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (461 aa) | ||||
rpsB | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (265 aa) | ||||
fliR | Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (255 aa) | ||||
CCUN_1547 | DNA topoisomerase IA. (655 aa) | ||||
flgE | Flagellar basal body protein. (543 aa) | ||||
fliK | Flagellar hook-length control protein. (687 aa) | ||||
rpsU | 30S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. (70 aa) | ||||
fliN | Flagellar motor switch protein. (102 aa) | ||||
fliY | Flagellar motor switch protein. (278 aa) | ||||
fliM | Flagellar motor switch protein. (358 aa) | ||||
rpsF | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (125 aa) | ||||
rpsR | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (86 aa) | ||||
rpmI | 50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (63 aa) | ||||
rplT | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (117 aa) | ||||
fliD | Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. (652 aa) | ||||
fliG | Flagellar motor switch protein FliG. (342 aa) | ||||
fliF | Flagellar M-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family. (561 aa) | ||||
rplY | 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (178 aa) | ||||
rpsJ | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa) | ||||
rplC | 50S ribosomal protein L3. (191 aa) | ||||
rplD | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (204 aa) | ||||
rplW | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (93 aa) | ||||
rplB | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (276 aa) | ||||
rpsS | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (93 aa) | ||||
rplV | 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (128 aa) | ||||
rpsC | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (232 aa) | ||||
rplP | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (141 aa) | ||||
rpmC | 50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (61 aa) | ||||
rpsQ | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (83 aa) | ||||
rplN | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa) | ||||
rplX | 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (77 aa) | ||||
rplE | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (183 aa) | ||||
rpsN | 30S ribosomal protein S14 type Z; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa) | ||||
rpsH | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (131 aa) | ||||
rplF | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa) | ||||
rplR | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (118 aa) | ||||
rpsE | 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (147 aa) | ||||
rplO | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (130 aa) | ||||
rpsI | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (129 aa) | ||||
rplM | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (141 aa) | ||||
rpmF | 50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (48 aa) | ||||
flgB | Flagellar basal body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body. (144 aa) | ||||
flgC | Flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family. (176 aa) | ||||
fliE | Flagellar hook-basal body complex protein FliE. (101 aa) | ||||
rpmJ | 50S ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (37 aa) | ||||
rpsM | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (121 aa) | ||||
rpsK | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (130 aa) | ||||
rpsD | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (208 aa) | ||||
rplQ | 50S ribosomal protein L17. (117 aa) | ||||
rpmE | 50S ribosomal protein L31; Binds the 23S rRNA. (66 aa) | ||||
fliQ | Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa) | ||||
dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (531 aa) | ||||
flaA | Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (597 aa) | ||||
flgK | Flagellar hook-associated protein; Belongs to the flagella basal body rod proteins family. (608 aa) | ||||
flgI | Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. (348 aa) |