(58 nodes) Carbohydrate catabolic process network (Thermoclostridium stercorarium)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	AGC67074.1	Oxidoreductase domain protein. (407 aa)
	AGC67127.1	alpha-1,2-L-fucosidase. (761 aa)
	AGC67186.1	Glycoside hydrolase family 2; Belongs to the glycosyl hydrolase 2 family. (903 aa)
	lacZ1	Beta-galactosidase LacZ; Belongs to the glycosyl hydrolase 2 family. (800 aa)
	bglZ	Beta-glucosidase BglZ; Belongs to the glycosyl hydrolase 3 family. (794 aa)
	bglB	Thermostable beta-glucosidase B; Belongs to the glycosyl hydrolase 3 family. (751 aa)
	agaR1	Alpha-galactosidase 1. (732 aa)
	AGC67515.1	Glucoside hyrolase family10. (493 aa)
	lacZ2	Beta-galactosidase LacZ. (1023 aa)
	apgM	2,3-bisphosphoglycerate-independent phosphoglycerate mutase ApgM. (401 aa)
	rhaA	L-rhamnose isomerase RhaA; Belongs to the rhamnose isomerase family. (425 aa)
	xynC1	Endo-1,4-beta-xylanase. (1032 aa)
	pfp	Pyrophosphate--fructose 6-phosphate 1-phosphotransferase Pfp; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (416 aa)
	xynB	Endo-1,4-beta-xylanase XynB. (387 aa)
	xynD	Arabinoxylan arabinofuranohydrolase XynD. (1221 aa)
	AGC67759.1	Endo-alpha-xylanase. (415 aa)
	Gck1	PfkB domain protein. (366 aa)
	uxaA	Altronate hydrolase UxaA. (499 aa)
	rhaB	Rhamnulokinase RhaB. (497 aa)
	kduI	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase KduI; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. (276 aa)
	bxlA	1,4-beta-xylosidase BxlA. (502 aa)
	deoC	Deoxyribose-phosphate aldolase DeoC; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (235 aa)
	AGC67967.1	Hypothetical protein. (686 aa)
	lacZ3	Beta-galactosidase LacZ; Belongs to the glycosyl hydrolase 2 family. (1146 aa)
	AGC68032.1	Oxidoreductase domain protein. (337 aa)
	AGC68049.1	Glycoside hydrolase family 101. (447 aa)
	AGC68055.1	Hypothetical protein. (504 aa)
	glpK1	Glycerol kinase 1. (434 aa)
	pgiB	Glucose-6-phosphate isomerase PgiB; Belongs to the GPI family. (450 aa)
	AGC68111.1	Glycoside hydrolase family 43; Belongs to the glycosyl hydrolase 43 family. (520 aa)
	manA1	Mannan endo-1,4-beta-mannosidase ManA; Belongs to the glycosyl hydrolase 26 family. (509 aa)
	AGC68205.1	Oxidoreductase domain protein. (342 aa)
	uidA	Beta-glucuronidase UidA; Belongs to the glycosyl hydrolase 2 family. (593 aa)
	AGC68403.1	Glycogen debranching enzyme. (654 aa)
	pfkA	6-phosphofructokinase PfkA; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (323 aa)
	AGC68543.1	Putative metal dependent hydrolase. (228 aa)
	AGC68583.1	Oxidoreductase domain-containing protein. (369 aa)
	araD	L-ribulose-5-phosphate 4-epimerase AraD. (228 aa)
	araB	Ribulokinase AraB. (558 aa)
	araA	L-arabinose isomerase AraA; Catalyzes the conversion of L-arabinose to L-ribulose. (495 aa)
	agaR3	Alpha-galactosidase 1. (736 aa)
	celZ	Endoglucanase Z. (986 aa)
	celY	Exoglucanase-2. (914 aa)
	xynA	Endo-1,4-beta-xylanase A; Belongs to the glycosyl hydrolase 11 (cellulase G) family. (651 aa)
	rpe	Ribulose-phosphate 3-epimerase Rpe; Belongs to the ribulose-phosphate 3-epimerase family. (232 aa)
	gpmI	2,3-bisphosphoglycerate-independent phosphoglycerate mutase GpmI; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (546 aa)
	tpiA	Triosephosphate isomerase TpiA; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa)
	pgk	Phosphoglycerate kinase Pgk; Belongs to the phosphoglycerate kinase family. (400 aa)
	ldh	L-lactate dehydrogenase Ldh; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (317 aa)
	pfkA2	6-phosphofructokinase 2; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate, the first committing step of glycolysis. (363 aa)
	eno	Enolase Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (438 aa)
	galT	Galactose-1-phosphate uridylyltransferase GalT. (323 aa)
	fucA	L-fuculose phosphate aldolase FucA. (429 aa)
	pyk	Pyruvate kinase Pyk; Belongs to the pyruvate kinase family. (587 aa)
	aguA	Alpha-glucuronidase AguA; Belongs to the glycosyl hydrolase 67 family. (682 aa)
	kdgK	2-keto-3-deoxygluconate kinase KdgK. (357 aa)
	RpiB	Sugar-phosphate isomerase, RpiB/LacA/LacB family. (149 aa)
	glpK	Glycerol kinase GlpK; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (497 aa)

Your Current Organism:

Thermoclostridium stercorarium

NCBI taxonomy Id: 1121335
Other names: Clostridium stercorarium subsp. stercorarium DSM 8532, T. stercorarium subsp. stercorarium DSM 8532, Thermoclostridium stercorarium subsp. stercorarium DSM 8532

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGC67074.1	AGC68032.1	Cst_c00420	Cst_c10340	Oxidoreductase domain protein.	Oxidoreductase domain protein.	0.713
AGC67074.1	AGC68205.1	Cst_c00420	Cst_c12100	Oxidoreductase domain protein.	Oxidoreductase domain protein.	0.779
AGC67074.1	Gck1	Cst_c00420	Cst_c08190	Oxidoreductase domain protein.	PfkB domain protein.	0.605
AGC67074.1	kdgK	Cst_c00420	Cst_c25270	Oxidoreductase domain protein.	2-keto-3-deoxygluconate kinase KdgK.	0.651
AGC67127.1	AGC67186.1	Cst_c00960	Cst_c01600	alpha-1,2-L-fucosidase.	Glycoside hydrolase family 2; Belongs to the glycosyl hydrolase 2 family.	0.481
AGC67127.1	AGC68049.1	Cst_c00960	Cst_c10510	alpha-1,2-L-fucosidase.	Glycoside hydrolase family 101.	0.656
AGC67127.1	AGC68055.1	Cst_c00960	Cst_c10570	alpha-1,2-L-fucosidase.	Hypothetical protein.	0.552
AGC67127.1	aguA	Cst_c00960	Cst_c23950	alpha-1,2-L-fucosidase.	Alpha-glucuronidase AguA; Belongs to the glycosyl hydrolase 67 family.	0.526
AGC67127.1	celY	Cst_c00960	Cst_c18970	alpha-1,2-L-fucosidase.	Exoglucanase-2.	0.664
AGC67127.1	lacZ1	Cst_c00960	Cst_c02440	alpha-1,2-L-fucosidase.	Beta-galactosidase LacZ; Belongs to the glycosyl hydrolase 2 family.	0.539
AGC67127.1	lacZ3	Cst_c00960	Cst_c09830	alpha-1,2-L-fucosidase.	Beta-galactosidase LacZ; Belongs to the glycosyl hydrolase 2 family.	0.585
AGC67127.1	manA1	Cst_c00960	Cst_c11340	alpha-1,2-L-fucosidase.	Mannan endo-1,4-beta-mannosidase ManA; Belongs to the glycosyl hydrolase 26 family.	0.504
AGC67127.1	xynA	Cst_c00960	Cst_c19320	alpha-1,2-L-fucosidase.	Endo-1,4-beta-xylanase A; Belongs to the glycosyl hydrolase 11 (cellulase G) family.	0.609
AGC67127.1	xynB	Cst_c00960	Cst_c07090	alpha-1,2-L-fucosidase.	Endo-1,4-beta-xylanase XynB.	0.679
AGC67127.1	xynC1	Cst_c00960	Cst_c06620	alpha-1,2-L-fucosidase.	Endo-1,4-beta-xylanase.	0.635
AGC67127.1	xynD	Cst_c00960	Cst_c07100	alpha-1,2-L-fucosidase.	Arabinoxylan arabinofuranohydrolase XynD.	0.534
AGC67186.1	AGC67127.1	Cst_c01600	Cst_c00960	Glycoside hydrolase family 2; Belongs to the glycosyl hydrolase 2 family.	alpha-1,2-L-fucosidase.	0.481
AGC67186.1	lacZ2	Cst_c01600	Cst_c06190	Glycoside hydrolase family 2; Belongs to the glycosyl hydrolase 2 family.	Beta-galactosidase LacZ.	0.483
AGC67186.1	lacZ3	Cst_c01600	Cst_c09830	Glycoside hydrolase family 2; Belongs to the glycosyl hydrolase 2 family.	Beta-galactosidase LacZ; Belongs to the glycosyl hydrolase 2 family.	0.559
AGC67515.1	aguA	Cst_c04930	Cst_c23950	Glucoside hyrolase family10.	Alpha-glucuronidase AguA; Belongs to the glycosyl hydrolase 67 family.	0.595

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