STRINGSTRING
AGG65516.1 AGG65516.1 AGG65517.1 AGG65517.1 AGG65524.1 AGG65524.1 AGG65525.1 AGG65525.1 AGG65581.1 AGG65581.1 panC panC panB panB panD panD AGG65630.1 AGG65630.1 gltD gltD pat pat AGG65650.1 AGG65650.1 gluQ gluQ leuA leuA AGG65677.1 AGG65677.1 asd asd AGG65680.1 AGG65680.1 AGG65736.1 AGG65736.1 AGG65742.1 AGG65742.1 AGG65746.1 AGG65746.1 AGG65747.1 AGG65747.1 AGG65748.1 AGG65748.1 AGG65776.1 AGG65776.1 AGG65777.1 AGG65777.1 AGG65781.1 AGG65781.1 sdhA sdhA AGG65783.1 AGG65783.1 gpmA gpmA proC proC hemA hemA hemC hemC aroQ aroQ AGG65824.1 AGG65824.1 AGG65826.1 AGG65826.1 hemE hemE AGG65831.1 AGG65831.1 hemL hemL menA menA AGG65843.1 AGG65843.1 menB menB menC menC menD menD ubiE ubiE AGG65858.1 AGG65858.1 adk adk guaB guaB AGG66031.1 AGG66031.1 metX metX AGG66064.1 AGG66064.1 AGG66079.1 AGG66079.1 AGG66086.1 AGG66086.1 AGG66093.1 AGG66093.1 AGG66099.1 AGG66099.1 AGG66100.1 AGG66100.1 purK purK purE purE AGG66118.1 AGG66118.1 manB manB AGG66124.1 AGG66124.1 aroA aroA AGG66168.1 AGG66168.1 AGG66244.1 AGG66244.1 gltA gltA pgi pgi AGG66266.1 AGG66266.1 purN purN purH purH AGG66289.1 AGG66289.1 ispE ispE AGG66313.1 AGG66313.1 AGG66338.1 AGG66338.1 prs prs eno eno AGG66377.1 AGG66377.1 AGG66378.1 AGG66378.1 glyA glyA fumC fumC glpX glpX ispH ispH AGG66438.1 AGG66438.1 AGG66471.1 AGG66471.1 AGG66498.1 AGG66498.1 glgC glgC AGG66513.1 AGG66513.1 AGG66520.1 AGG66520.1 lysA lysA AGG66554.1 AGG66554.1 thrB thrB glgB glgB pfkA pfkA ilvD ilvD AGG66623.1 AGG66623.1 ilvH ilvH ilvC ilvC AGG66629.1 AGG66629.1 leuB leuB AGG66634.1 AGG66634.1 AGG66637.1 AGG66637.1 gltX gltX AGG66655.1 AGG66655.1 leuC leuC leuD leuD gpsA gpsA AGG66686.1 AGG66686.1 AGG66714.1 AGG66714.1 argC argC argJ argJ argB argB argD argD AGG66736.1 AGG66736.1 argG argG argH argH AGG66781.1 AGG66781.1 hisG hisG hisE hisE AGG66829.1 AGG66829.1 hemH hemH AGG66929.1 AGG66929.1 ctaB ctaB AGG66932.1 AGG66932.1 tal tal zwf zwf pgl pgl AGG66938.1 AGG66938.1 tpiA tpiA pgk pgk AGG66944.1 AGG66944.1 ribH ribH ribBA ribBA AGG66952.1 AGG66952.1 AGG66953.1 AGG66953.1 AGG66954.1 AGG66954.1 metK metK aroB aroB aroK aroK aroC aroC aroE aroE AGG67001.1 AGG67001.1 dxs dxs AGG67039.1 AGG67039.1 AGG67040.1 AGG67040.1 dapF dapF miaA miaA dapA dapA dapB dapB AGG67105.1 AGG67105.1 AGG67124.1 AGG67124.1 AGG67125.1 AGG67125.1 mqo mqo ispG ispG dxr dxr AGG67147.1 AGG67147.1 AGG67189.1 AGG67189.1 AGG67192.1 AGG67192.1 AGG67194.1 AGG67194.1 AGG67196.1 AGG67196.1 hisI hisI hisF hisF AGG67200.1 AGG67200.1 hisA hisA hisH hisH hisB hisB hisC hisC hisD hisD AGG67212.1 AGG67212.1 AGG67217.1 AGG67217.1 AGG67224.1 AGG67224.1 ilvA ilvA AGG67230.1 AGG67230.1 AGG67239.1 AGG67239.1 AGG67268.1 AGG67268.1 AGG67274.1 AGG67274.1 AGG67279.1 AGG67279.1 AGG67280.1 AGG67280.1 AGG67290.1 AGG67290.1 AGG67295.1 AGG67295.1 aceF aceF AGG67310.1 AGG67310.1 AGG67314.1 AGG67314.1 AGG67325.1 AGG67325.1 aceE aceE acpP acpP AGG67358.1 AGG67358.1 AGG67372.1 AGG67372.1 AGG67378.1 AGG67378.1 idi idi AGG67384.1 AGG67384.1 AGG67395.1 AGG67395.1 glcB glcB AGG67397.1 AGG67397.1 proA proA proB proB ndk ndk mdh mdh AGG67449.1 AGG67449.1 AGG67472.1 AGG67472.1 AGG67487.1 AGG67487.1 AGG67519.1 AGG67519.1 AGG67548.1 AGG67548.1 AGG67563.1 AGG67563.1 ilvD-2 ilvD-2 AGG67575.1 AGG67575.1 AGG67576.1 AGG67576.1 sucD sucD sucC sucC AGG67582.1 AGG67582.1 purM purM purF purF purL purL purQ purQ purS purS purC purC AGG67611.1 AGG67611.1 purD purD AGG67643.1 AGG67643.1 AGG67645.1 AGG67645.1 AGG67653.1 AGG67653.1 AGG67656.1 AGG67656.1 AGG67657.1 AGG67657.1 ispF ispF ispD ispD AGG67676.1 AGG67676.1 AGG67681.1 AGG67681.1 AGG67690.1 AGG67690.1 AGG67715.1 AGG67715.1 AGG67743.1 AGG67743.1 purT purT AGG67763.1 AGG67763.1 AGG67779.1 AGG67779.1 AGG67785.1 AGG67785.1 AGG67789.1 AGG67789.1 AGG67790.1 AGG67790.1 AGG67812.1 AGG67812.1 pckG pckG pheA pheA AGG67878.1 AGG67878.1 ldh ldh AGG67935.1 AGG67935.1 AGG67943.1 AGG67943.1 AGG67965.1 AGG67965.1 AGG67966.1 AGG67966.1 trpD trpD trpF trpF trpB trpB trpA trpA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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AGG65516.1Cystathionine beta-synthase; COG0031 Cysteine synthase. (335 aa)
AGG65517.1COG4529 Uncharacterized protein conserved in bacteria. (921 aa)
AGG65524.1COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (361 aa)
AGG65525.1COG1562 Phytoene/squalene synthetase. (299 aa)
AGG65581.1COG0506 Proline dehydrogenase; Belongs to the aldehyde dehydrogenase family. (1160 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (275 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (271 aa)
panDAspartate alpha-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (136 aa)
AGG65630.1Hypothetical protein; COG0067 Glutamate synthase domain 1. (1510 aa)
gltDCOG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (506 aa)
patAminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (341 aa)
AGG65650.1COG0287 Prephenate dehydrogenase. (340 aa)
gluQglutamyl-Q tRNA(Asp) ligase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (294 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (616 aa)
AGG65677.1COG0527 Aspartokinases; Belongs to the aspartokinase family. (421 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (343 aa)
AGG65680.1COG0753 Catalase. (517 aa)
AGG65736.1COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases; Belongs to the 5'-nucleotidase family. (680 aa)
AGG65742.1Hypothetical protein; COG1064 Zn-dependent alcohol dehydrogenases. (377 aa)
AGG65746.1Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (287 aa)
AGG65747.1dTDP-4-dehydrorhamnose 3,5-epimerase, dTDP-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (451 aa)
AGG65748.1COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (339 aa)
AGG65776.1COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (469 aa)
AGG65777.1UTP-glucose-1-phosphate uridylyltransferase; COG1210 UDP-glucose pyrophosphorylase. (308 aa)
AGG65781.1Hypothetical protein. (257 aa)
sdhACOG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (670 aa)
AGG65783.1COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (249 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (464 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (298 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (146 aa)
AGG65824.1uroporphyrin-III C-methyltransferase; COG0007 Uroporphyrinogen-III methylase. (594 aa)
AGG65826.1COG0113 Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (337 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (358 aa)
AGG65831.1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (453 aa)
hemLCOG0001 Glutamate-1-semialdehyde aminotransferase. (455 aa)
menA1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (303 aa)
AGG65843.1O-succinylbenzoic acid--CoA ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II. (376 aa)
menBNaphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (319 aa)
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (338 aa)
menD2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (542 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (230 aa)
AGG65858.1COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (350 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (184 aa)
guaBInosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (506 aa)
AGG66031.1Inosine 5-monophosphate dehydrogenase; COG0516 IMP dehydrogenase/GMP reductase. (389 aa)
metXHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (377 aa)
AGG66064.1COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (738 aa)
AGG66079.1COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. (395 aa)
AGG66086.1Phosphoglucomutase/phosphomannomutase; COG1109 Phosphomannomutase. (530 aa)
AGG66093.1Hypothetical protein; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. (591 aa)
AGG66099.1Hypothetical protein; COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (537 aa)
AGG66100.1Hypothetical protein; COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (543 aa)
purKPhosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (409 aa)
purEPhosphoribosylaminoimidazole carboxylase catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (165 aa)
AGG66118.1Hypothetical protein; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon). (362 aa)
manBPhosphomannomutase/phosphoglucomutase; COG1109 Phosphomannomutase. (458 aa)
AGG66124.1COG1482 Phosphomannose isomerase. (394 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (427 aa)
AGG66168.1Hypothetical protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (262 aa)
AGG66244.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (376 aa)
gltACOG0372 Citrate synthase; Belongs to the citrate synthase family. (431 aa)
pgiCOG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. (540 aa)
AGG66266.1Hypothetical protein; COG1605 Chorismate mutase. (101 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (199 aa)
purHBifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful). (520 aa)
AGG66289.1Hypothetical protein; COG1210 UDP-glucose pyrophosphorylase. (311 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (312 aa)
AGG66313.13-hydroxyisobutyryl-CoA hydrolase; COG1024 Enoyl-CoA hydratase/carnithine racemase. (338 aa)
AGG66338.1COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (480 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
AGG66377.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (366 aa)
AGG66378.1Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (256 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (434 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (469 aa)
glpXCOG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins. (335 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (325 aa)
AGG66438.1COG1239 Mg-chelatase subunit ChlI. (456 aa)
AGG66471.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (303 aa)
AGG66498.1COG1621 Beta-fructosidases (levanase/invertase); Belongs to the glycosyl hydrolase 32 family. (501 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (409 aa)
AGG66513.1COG0169 Shikimate 5-dehydrogenase. (268 aa)
AGG66520.15-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (746 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (455 aa)
AGG66554.1COG0460 Homoserine dehydrogenase. (445 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa)
glgBGlycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (731 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (343 aa)
ilvDCOG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (613 aa)
AGG66623.1Acetolactate synthase 1 catalytic subunit; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. (626 aa)
ilvHCOG0440 Acetolactate synthase, small (regulatory) subunit. (172 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
AGG66629.1COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (340 aa)
AGG66634.1COG0500 SAM-dependent methyltransferases. (200 aa)
AGG66637.1COG1169 Isochorismate synthase. (376 aa)
gltXglutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (493 aa)
AGG66655.1Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (796 aa)
leuCIsopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (481 aa)
leuDIsopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa)
gpsACOG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (332 aa)
AGG66686.1Hypothetical protein; COG2021 Homoserine acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family. (349 aa)
AGG66714.1Hypothetical protein; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. (281 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (347 aa)
argJBifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (388 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (317 aa)
argDCOG4992 Ornithine/acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (401 aa)
AGG66736.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (319 aa)
argGCOG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (401 aa)
argHCOG0165 Argininosuccinate lyase. (477 aa)
AGG66781.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (484 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (281 aa)
hisECOG0140 Phosphoribosyl-ATP pyrophosphohydrolase. (87 aa)
AGG66829.1Methionine synthase I cobalamin-binding subunit; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1221 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (369 aa)
AGG66929.1COG1612 Uncharacterized protein required for cytochrome oxidase assembly. (336 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (296 aa)
AGG66932.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (697 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (360 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (511 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (236 aa)
AGG66938.1COG2423 Predicted ornithine cyclodeaminase, mu-crystallin homolog. (382 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (259 aa)
pgkCOG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (405 aa)
AGG66944.1COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (159 aa)
ribBABifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (423 aa)
AGG66952.1COG0307 Riboflavin synthase alpha chain. (204 aa)
AGG66953.1Bifunctional riboflavin-specific deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (332 aa)
AGG66954.1COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (220 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (407 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (366 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (200 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (383 aa)
aroECOG0169 Shikimate 5-dehydrogenase. (278 aa)
AGG67001.1COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (449 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (637 aa)
AGG67039.1Inositol monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (282 aa)
AGG67040.1Polyphosphate glucokinase; COG1940 Transcriptional regulator/sugar kinase. (250 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (277 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (302 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (301 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (248 aa)
AGG67105.1Bifunctional riboflavin kinase/FMN adenylyltransferase; COG0196 FAD synthase; Belongs to the ribF family. (341 aa)
AGG67124.1Hypothetical protein; COG1239 Mg-chelatase subunit ChlI. (368 aa)
AGG67125.1COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. (251 aa)
mqoMalate:quinone oxidoreductase; COG0579 Predicted dehydrogenase. (499 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (393 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (390 aa)
AGG67147.1Hypothetical protein; COG0575 CDP-diglyceride synthetase; Belongs to the CDS family. (297 aa)
AGG67189.1Hypothetical protein; COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family. (366 aa)
AGG67192.1COG0058 Glucan phosphorylase. (842 aa)
AGG67194.1COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (474 aa)
AGG67196.1COG0134 Indole-3-glycerol phosphate synthase. (261 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (118 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
AGG67200.1Myo-inositol-1(or 4)-monophosphatase; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. (262 aa)
hisACOG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. (246 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa)
hisBCOG0131 Imidazoleglycerol-phosphate dehydratase. (200 aa)
hisCCOG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (372 aa)
hisDBifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (442 aa)
AGG67212.1Hypothetical protein; COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Belongs to the glycosyl hydrolase 13 family. (849 aa)
AGG67217.1COG3280 Maltooligosyl trehalose synthase. (813 aa)
AGG67224.1Hypothetical protein; COG0296 1,4-alpha-glucan branching enzyme. (573 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (423 aa)
AGG67230.1COG0620 Methionine synthase II (cobalamin-independent). (401 aa)
AGG67239.1Hypothetical protein; COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D. (343 aa)
AGG67268.1Hypothetical protein; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (366 aa)
AGG67274.1Phospho-2-dehydro-3-deoxyheptonate aldolase; COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the class-II DAHP synthase family. (462 aa)
AGG67279.1COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase. (244 aa)
AGG67280.1COG1940 Transcriptional regulator/sugar kinase. (320 aa)
AGG67290.1COG0367 Asparagine synthase (glutamine-hydrolyzing). (640 aa)
AGG67295.1COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase. (367 aa)
aceFCOG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (692 aa)
AGG67310.1COG0498 Threonine synthase. (481 aa)
AGG67314.1COG5398 Heme oxygenase. (215 aa)
AGG67325.1Hypothetical protein; COG0546 Predicted phosphatases. (218 aa)
aceEPyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (922 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (124 aa)
AGG67358.1Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (249 aa)
AGG67372.1COG1640 4-alpha-glucanotransferase. (715 aa)
AGG67378.1Trehalose synthase; COG0366 Glycosidases. (601 aa)
idiIsopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (188 aa)
AGG67384.1Hypothetical protein; COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities. (368 aa)
AGG67395.1Hypothetical protein; COG0676 Uncharacterized enzymes related to aldose 1-epimerase. (253 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (737 aa)
AGG67397.1COG2224 Isocitrate lyase. (432 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (432 aa)
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (431 aa)
ndkMulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (136 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (323 aa)
AGG67449.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (410 aa)
AGG67472.1COG0698 Ribose 5-phosphate isomerase RpiB. (157 aa)
AGG67487.1COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases. (386 aa)
AGG67519.1Gluconokinase; COG3265 Gluconate kinase. (176 aa)
AGG67548.1Phosphoserine phosphatase; COG3830 ACT domain-containing protein. (431 aa)
AGG67563.1COG0033 Phosphoglucomutase. (546 aa)
ilvD-2COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (572 aa)
AGG67575.1COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)
AGG67576.1COG1045 Serine acetyltransferase. (188 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (395 aa)
AGG67582.1Succinate CoA transferase; COG0427 Acetyl-CoA hydrolase. (502 aa)
purMCOG0150 Phosphoribosylaminoimidazole (AIR) synthetase. (358 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (512 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (762 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (223 aa)
purSPhosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (81 aa)
purCCOG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Belongs to the SAICAR synthetase family. (297 aa)
AGG67611.1COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (476 aa)
purDCOG0151 Phosphoribosylamine-glycine ligase; Belongs to the GARS family. (421 aa)
AGG67643.1COG0380 Trehalose-6-phosphate synthase. (487 aa)
AGG67645.1Trehalose-6-phosphate phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. (256 aa)
AGG67653.1Sucrose-6-phosphate hydrolase; COG1621 Beta-fructosidases (levanase/invertase). (421 aa)
AGG67656.1Hypothetical protein; COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (314 aa)
AGG67657.1COG1940 Transcriptional regulator/sugar kinase. (307 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (160 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (256 aa)
AGG67676.1Inosine 5-monophosphate dehydrogenase; COG0516 IMP dehydrogenase/GMP reductase. (477 aa)
AGG67681.1Pantoate--beta-alanine ligase; COG0414 Panthothenate synthetase; Belongs to the pantothenate synthetase family. (272 aa)
AGG67690.1COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (194 aa)
AGG67715.1Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (741 aa)
AGG67743.1COG0454 Histone acetyltransferase HPA2 and related acetyltransferases. (338 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (404 aa)
AGG67763.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (344 aa)
AGG67779.1Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. (506 aa)
AGG67785.1COG1064 Zn-dependent alcohol dehydrogenases. (345 aa)
AGG67789.1Sulfate adenyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (437 aa)
AGG67790.1Sulfate adenylyltransferase subunit 2; COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes. (304 aa)
AGG67812.1Aminotransferase AlaT; COG0436 Aspartate/tyrosine/aromatic aminotransferase. (437 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (610 aa)
pheACOG0077 Prephenate dehydratase. (314 aa)
AGG67878.1COG0469 Pyruvate kinase. (617 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (315 aa)
AGG67935.1COG1260 Myo-inositol-1-phosphate synthase. (363 aa)
AGG67943.1Hypothetical protein; COG1070 Sugar (pentulose and hexulose) kinases. (495 aa)
AGG67965.1COG0147 Anthranilate/para-aminobenzoate synthases component I. (518 aa)
AGG67966.1COG0512 Anthranilate/para-aminobenzoate synthases component II. (208 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (346 aa)
trpFBifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; COG0134 Indole-3-glycerol phosphate synthase; Belongs to the TrpF family. (474 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (423 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (280 aa)
Your Current Organism:
Corynebacterium callunae
NCBI taxonomy Id: 1121353
Other names: C. callunae DSM 20147, Corynebacterium callunae DSM 20147
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