STRINGSTRING
AGG65498.1 AGG65498.1 AGG65680.1 AGG65680.1 AGG65738.1 AGG65738.1 AGG65776.1 AGG65776.1 AGG65781.1 AGG65781.1 sdhA sdhA AGG65783.1 AGG65783.1 gpmA gpmA folD folD AGG66064.1 AGG66064.1 AGG66089.1 AGG66089.1 AGG66093.1 AGG66093.1 AGG66099.1 AGG66099.1 AGG66100.1 AGG66100.1 AGG66244.1 AGG66244.1 gltA gltA pgi pgi AGG66338.1 AGG66338.1 prs prs eno eno glyA glyA fumC fumC glpX glpX pfkA pfkA AGG66629.1 AGG66629.1 AGG66781.1 AGG66781.1 AGG66932.1 AGG66932.1 tal tal zwf zwf pgl pgl ppc ppc tpiA tpiA pgk pgk AGG66944.1 AGG66944.1 AGG66954.1 AGG66954.1 AGG67001.1 AGG67001.1 AGG67040.1 AGG67040.1 mqo mqo AGG67194.1 AGG67194.1 ilvA ilvA AGG67267.1 AGG67267.1 AGG67280.1 AGG67280.1 aceF aceF aceE aceE glcB glcB AGG67397.1 AGG67397.1 mdh mdh AGG67449.1 AGG67449.1 AGG67472.1 AGG67472.1 AGG67519.1 AGG67519.1 AGG67548.1 AGG67548.1 AGG67575.1 AGG67575.1 AGG67576.1 AGG67576.1 sucD sucD sucC sucC AGG67582.1 AGG67582.1 AGG67657.1 AGG67657.1 AGG67715.1 AGG67715.1 ackA ackA eutD eutD AGG67763.1 AGG67763.1 AGG67878.1 AGG67878.1 AGG67943.1 AGG67943.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGG65498.1Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. (517 aa)
AGG65680.1COG0753 Catalase. (517 aa)
AGG65738.1Glutathione-independent formaldehyde dehydrogenase; COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. (397 aa)
AGG65776.1COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (469 aa)
AGG65781.1Hypothetical protein. (257 aa)
sdhACOG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. (670 aa)
AGG65783.1COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit. (249 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
AGG66064.1COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (738 aa)
AGG66089.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1140 aa)
AGG66093.1Hypothetical protein; COG4770 Acetyl/propionyl-CoA carboxylase, alpha subunit. (591 aa)
AGG66099.1Hypothetical protein; COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (537 aa)
AGG66100.1Hypothetical protein; COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta). (543 aa)
AGG66244.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (376 aa)
gltACOG0372 Citrate synthase; Belongs to the citrate synthase family. (431 aa)
pgiCOG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family. (540 aa)
AGG66338.1COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (480 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (325 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (425 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (434 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (469 aa)
glpXCOG1494 Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins. (335 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (343 aa)
AGG66629.1COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)
AGG66781.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (484 aa)
AGG66932.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (697 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (360 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (511 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (236 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (919 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (259 aa)
pgkCOG0126 3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (405 aa)
AGG66944.1COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
AGG66954.1COG0036 Pentose-5-phosphate-3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (220 aa)
AGG67001.1COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (449 aa)
AGG67040.1Polyphosphate glucokinase; COG1940 Transcriptional regulator/sugar kinase. (250 aa)
mqoMalate:quinone oxidoreductase; COG0579 Predicted dehydrogenase. (499 aa)
AGG67194.1COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. (474 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (423 aa)
AGG67267.1Hypothetical protein; COG0685 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (326 aa)
AGG67280.1COG1940 Transcriptional regulator/sugar kinase. (320 aa)
aceFCOG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes. (692 aa)
aceEPyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (922 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (737 aa)
AGG67397.1COG2224 Isocitrate lyase. (432 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (323 aa)
AGG67449.1COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (410 aa)
AGG67472.1COG0698 Ribose 5-phosphate isomerase RpiB. (157 aa)
AGG67519.1Gluconokinase; COG3265 Gluconate kinase. (176 aa)
AGG67548.1Phosphoserine phosphatase; COG3830 ACT domain-containing protein. (431 aa)
AGG67575.1COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)
AGG67576.1COG1045 Serine acetyltransferase. (188 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (395 aa)
AGG67582.1Succinate CoA transferase; COG0427 Acetyl-CoA hydrolase. (502 aa)
AGG67657.1COG1940 Transcriptional regulator/sugar kinase. (307 aa)
AGG67715.1Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (741 aa)
ackAAcetate kinase A/propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)
eutDCOG0280 Phosphotransacetylase. (460 aa)
AGG67763.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (344 aa)
AGG67878.1COG0469 Pyruvate kinase. (617 aa)
AGG67943.1Hypothetical protein; COG1070 Sugar (pentulose and hexulose) kinases. (495 aa)
Your Current Organism:
Corynebacterium callunae
NCBI taxonomy Id: 1121353
Other names: C. callunae DSM 20147, Corynebacterium callunae DSM 20147
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