STRINGSTRING
SHI54929.1 SHI54929.1 metK metK cysS cysS SHJ19532.1 SHJ19532.1 SHJ24091.1 SHJ24091.1 SHJ60679.1 SHJ60679.1 SHJ60837.1 SHJ60837.1 SHJ65796.1 SHJ65796.1 SHJ65936.1 SHJ65936.1 SHJ66555.1 SHJ66555.1 SHJ66597.1 SHJ66597.1 SHJ68465.1 SHJ68465.1 asd asd argC argC argJ argJ SHJ79823.1 SHJ79823.1 SHK04792.1 SHK04792.1 SHK06455.1 SHK06455.1 SHK28135.1 SHK28135.1 SHK32517.1 SHK32517.1 SHK32692.1 SHK32692.1 SHK33714.1 SHK33714.1 dapA dapA SHK43497.1 SHK43497.1 cysS-2 cysS-2 argB argB argD argD SHK51841.1 SHK51841.1 argG argG argH argH lysA lysA dapF dapF dapL dapL serC serC SHK70007.1 SHK70007.1 SHK70336.1 SHK70336.1 SHK71800.1 SHK71800.1 SHK77701.1 SHK77701.1 SHK77743.1 SHK77743.1 SHK77787.1 SHK77787.1 SHK83771.1 SHK83771.1 SHK83817.1 SHK83817.1 ahcY ahcY metK-2 metK-2 SHK98595.1 SHK98595.1 SHL20497.1 SHL20497.1 metK-3 metK-3 SHL40004.1 SHL40004.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHI54929.1Methionine synthase II (cobalamin-independent). (361 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (389 aa)
cysScysteinyl-tRNA synthetase. (764 aa)
SHJ19532.1L-alanine dehydrogenase. (373 aa)
SHJ24091.14-hydroxy-tetrahydrodipicolinate reductase; Belongs to the DapB family. (276 aa)
SHJ60679.1N-acetylglutamate synthase, GNAT family. (160 aa)
SHJ60837.1L-threonine synthase. (501 aa)
SHJ65796.1Ribosomal protein S6--L-glutamate ligase. (276 aa)
SHJ65936.1Aspartate/methionine/tyrosine aminotransferase. (380 aa)
SHJ66555.1Cysteine synthase. (307 aa)
SHJ66597.1Serine O-acetyltransferase. (315 aa)
SHJ68465.1Hypothetical protein. (341 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (373 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (350 aa)
argJGlutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (395 aa)
SHJ79823.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (363 aa)
SHK04792.1N-acetylglutamate synthase; Belongs to the acetyltransferase family. (149 aa)
SHK06455.1Aspartate aminotransferase. (393 aa)
SHK28135.1Acetyltransferase (GNAT) family protein. (141 aa)
SHK32517.1Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (388 aa)
SHK32692.1Cystathione beta-lyase. (390 aa)
SHK33714.1Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase. (435 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (344 aa)
SHK43497.1Succinyl-diaminopimelate desuccinylase. (422 aa)
cysS-2cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (474 aa)
argBN-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (270 aa)
argDAcetylornithine aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (395 aa)
SHK51841.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (306 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (400 aa)
argHArgininosuccinate lyase. (465 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (419 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (278 aa)
dapLLL-diaminopimelate aminotransferase apoenzyme; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (388 aa)
serCPhosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa)
SHK70007.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa)
SHK70336.1Aspartate aminotransferase. (423 aa)
SHK71800.1Aspartate kinase; Belongs to the aspartokinase family. (405 aa)
SHK77701.1Alanine-synthesizing transaminase. (388 aa)
SHK77743.1Homoserine dehydrogenase. (442 aa)
SHK77787.1Phosphoserine phosphatase. (207 aa)
SHK83771.1Putative NADPH-quinone reductase (modulator of drug activity B). (197 aa)
SHK83817.1Cystathionine beta-lyase. (375 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (469 aa)
metK-2Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (393 aa)
SHK98595.1Ornithine decarboxylase. (390 aa)
SHL20497.1Aminotransferase. (384 aa)
metK-3Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (399 aa)
SHL40004.1Diaminopimelate decarboxylase. (402 aa)
Your Current Organism:
Desulfatibacillum alkenivorans DSM 16219
NCBI taxonomy Id: 1121393
Other names: D. alkenivorans DSM 16219
Server load: low (16%) [HD]