42 items (Desulfatibacillum alkenivorans DSM 16219)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	SHK71800.1	Aspartate kinase; Belongs to the aspartokinase family. (405 aa)
	SHK76593.1	Methyltetrahydrofolate--corrinoid iron-sulfur protein Co-methyltransferase. (293 aa)
	SHL07845.1	Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain. (537 aa)
	SHL07796.1	5-methyltetrahydrofolate--homocysteine methyltransferase. (268 aa)
	SHK77743.1	Homoserine dehydrogenase. (442 aa)
	SHK77701.1	Alanine-synthesizing transaminase. (388 aa)
	SHI92142.1	Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain. (524 aa)
	SHI62484.1	5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family. (291 aa)
	SHI59599.1	Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain. (595 aa)
	SHI54929.1	Methionine synthase II (cobalamin-independent). (361 aa)
	SHI50158.1	Homoserine kinase type II. (323 aa)
	SHI49789.1	Hypothetical protein. (234 aa)
	SHL40004.1	Diaminopimelate decarboxylase. (402 aa)
	SHL31154.1	5-methyltetrahydrofolate--homocysteine methyltransferase. (266 aa)
	SHL07878.1	Vitamin B12 dependent methionine synthase, activation domain. (233 aa)
	lysA	Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (419 aa)
	dapA	4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (344 aa)
	SHK33714.1	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase. (435 aa)
	SHK28652.1	5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase. (262 aa)
	SHK22593.1	Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain. (520 aa)
	SHK22557.1	5-methyltetrahydrofolate--homocysteine methyltransferase. (269 aa)
	SHK22087.1	Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (273 aa)
	SHK15292.1	2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphatephosphatase. (214 aa)
	SHK10834.1	Aspartate kinase. (472 aa)
	SHJ85776.1	Vitamin B12 dependent methionine synthase, activation domain. (225 aa)
	SHJ75450.1	Diaminopimelate decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (443 aa)
	SHJ73942.1	Methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. (548 aa)
	SHJ73655.1	Uncharacterized conserved protein, DUF39 family. (387 aa)
	asd	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (373 aa)
	SHJ68465.1	Hypothetical protein. (341 aa)
	folD	Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (302 aa)
	SHJ65128.1	5-methyltetrahydrofolate--homocysteine methyltransferase. (275 aa)
	SHJ60837.1	L-threonine synthase. (501 aa)
	SHJ58799.1	Hypothetical protein. (67 aa)
	SHJ24091.1	4-hydroxy-tetrahydrodipicolinate reductase; Belongs to the DapB family. (276 aa)
	SHJ19119.1	Hypothetical protein. (61 aa)
	SHJ08605.1	Methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family. (545 aa)
	mtnA	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (369 aa)
	dapF	Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (278 aa)
	dapL	LL-diaminopimelate aminotransferase apoenzyme; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (388 aa)
	SHK68228.1	Hypothetical protein. (598 aa)
	SHK76390.1	Uncharacterized 2Fe-2 and 4Fe-4S clusters-containing protein, contains DUF4445 domain. (653 aa)

Your Current Organism:

Desulfatibacillum alkenivorans DSM 16219

NCBI taxonomy Id: 1121393
Other names: D. alkenivorans DSM 16219

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SHI50158.1	SHI54929.1	SAMN02745216_00029	SAMN02745216_00126	Homoserine kinase type II.	Methionine synthase II (cobalamin-independent).	0.587
SHI50158.1	SHI62484.1	SAMN02745216_00029	SAMN02745216_00284	Homoserine kinase type II.	5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family.	0.504
SHI50158.1	SHJ08605.1	SAMN02745216_00029	SAMN02745216_00996	Homoserine kinase type II.	Methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family.	0.610
SHI50158.1	SHJ60837.1	SAMN02745216_00029	SAMN02745216_01959	Homoserine kinase type II.	L-threonine synthase.	0.768
SHI50158.1	SHJ68465.1	SAMN02745216_00029	SAMN02745216_02087	Homoserine kinase type II.	Hypothetical protein.	0.521
SHI50158.1	SHJ73942.1	SAMN02745216_00029	SAMN02745216_02167	Homoserine kinase type II.	Methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family.	0.514
SHI50158.1	SHK10834.1	SAMN02745216_00029	SAMN02745216_02887	Homoserine kinase type II.	Aspartate kinase.	0.634
SHI50158.1	SHK71800.1	SAMN02745216_00029	SAMN02745216_03968	Homoserine kinase type II.	Aspartate kinase; Belongs to the aspartokinase family.	0.634
SHI50158.1	SHK77701.1	SAMN02745216_00029	SAMN02745216_04067	Homoserine kinase type II.	Alanine-synthesizing transaminase.	0.431
SHI50158.1	SHK77743.1	SAMN02745216_00029	SAMN02745216_04068	Homoserine kinase type II.	Homoserine dehydrogenase.	0.696
SHI50158.1	dapL	SAMN02745216_00029	SAMN02745216_03600	Homoserine kinase type II.	LL-diaminopimelate aminotransferase apoenzyme; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate.	0.431
SHI54929.1	SHI50158.1	SAMN02745216_00126	SAMN02745216_00029	Methionine synthase II (cobalamin-independent).	Homoserine kinase type II.	0.587
SHI54929.1	SHI62484.1	SAMN02745216_00126	SAMN02745216_00284	Methionine synthase II (cobalamin-independent).	5,10-methylenetetrahydrofolate reductase (NAD(P)); Belongs to the methylenetetrahydrofolate reductase family.	0.858
SHI54929.1	SHJ08605.1	SAMN02745216_00126	SAMN02745216_00996	Methionine synthase II (cobalamin-independent).	Methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family.	0.703
SHI54929.1	SHJ60837.1	SAMN02745216_00126	SAMN02745216_01959	Methionine synthase II (cobalamin-independent).	L-threonine synthase.	0.594
SHI54929.1	SHJ65128.1	SAMN02745216_00126	SAMN02745216_02005	Methionine synthase II (cobalamin-independent).	5-methyltetrahydrofolate--homocysteine methyltransferase.	0.638
SHI54929.1	SHJ73942.1	SAMN02745216_00126	SAMN02745216_02167	Methionine synthase II (cobalamin-independent).	Methyltransferase, MtaA/CmuA family; Belongs to the uroporphyrinogen decarboxylase family.	0.703
SHI54929.1	SHJ85776.1	SAMN02745216_00126	SAMN02745216_02404	Methionine synthase II (cobalamin-independent).	Vitamin B12 dependent methionine synthase, activation domain.	0.586
SHI54929.1	SHK10834.1	SAMN02745216_00126	SAMN02745216_02887	Methionine synthase II (cobalamin-independent).	Aspartate kinase.	0.690
SHI54929.1	SHK22557.1	SAMN02745216_00126	SAMN02745216_03112	Methionine synthase II (cobalamin-independent).	5-methyltetrahydrofolate--homocysteine methyltransferase.	0.586