STRINGSTRING
CCO22307.1 CCO22307.1 pta pta plsX plsX fabH fabH fabG fabG fabF fabF CCO22553.1 CCO22553.1 argJ argJ srpH srpH CCO23002.1 CCO23002.1 CCO23151.1 CCO23151.1 fabD fabD CCO23183.1 CCO23183.1 fabH-2 fabH-2 CCO23208.1 CCO23208.1 CCO23219.1 CCO23219.1 CCO23233.1 CCO23233.1 lpxD-2 lpxD-2 CCO23246.1 CCO23246.1 glmU glmU FabF FabF CCO23425.1 CCO23425.1 CCO23432.1 CCO23432.1 FabF-2 FabF-2 fabB fabB fabG-2 fabG-2 CCO23571.1 CCO23571.1 pduL pduL CCO23851.1 CCO23851.1 lipB lipB CCO24214.1 CCO24214.1 lnt lnt gcp gcp fabI fabI CCO24585.1 CCO24585.1 pta-2 pta-2 CCO25060.1 CCO25060.1 ptb ptb plsY plsY bioF bioF lpxD lpxD fabZ fabZ lpxA lpxA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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CCO22307.1Putative 3-Oxoacyl-(Acyl-carrier-protein (ACP)) synthase III domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (316 aa)
ptaPhosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (704 aa)
plsXPhosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (341 aa)
fabH3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (328 aa)
fabG3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (247 aa)
fabF3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (412 aa)
CCO22553.1Homologs of previously reported genes of unknown function. (93 aa)
argJArginine biosynthesis bifunctional protein ArgJ [Includes: Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (394 aa)
srpHSerine acetyltransferase, plasmid. (295 aa)
CCO23002.1Homologs of previously reported genes of unknown function. (131 aa)
CCO23151.1Homologs of previously reported genes of unknown function. (897 aa)
fabDAcyl transferase; Function of strongly homologous gene; enzyme. (307 aa)
CCO23183.1Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the acetyltransferase family. (152 aa)
fabH-2Beta-ketoacyl-acyl-carrier-protein synthase III; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (324 aa)
CCO23208.1Putative UDP-3-O-acylglucosamine N-acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (288 aa)
CCO23219.1Protein of unknown function; No homology to any previously reported sequences. (325 aa)
CCO23233.1Protein of unknown function; No homology to any previously reported sequences. (137 aa)
lpxD-2UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (298 aa)
CCO23246.1Transferase hexapeptide repeat containing protein. (211 aa)
glmUFused N-acetyl glucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (460 aa)
FabFBeta-ketoacyl synthase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (396 aa)
CCO23425.1Beta-hydroxyacyl-(Acyl-carrier-protein) dehydratase FabA/FabZ. (129 aa)
CCO23432.1Putative Phospholipid/glycerol acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (252 aa)
FabF-2Beta-ketoacyl synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (400 aa)
fabBBeta-ketoacyl synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (404 aa)
fabG-23-oxoacyl-[acyl-carrier-protein] reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (240 aa)
CCO23571.1DRTGG domain protein. (354 aa)
pduLPhosphate propanoyltransferase; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (233 aa)
CCO23851.1DRTGG domain protein. (355 aa)
lipBOctanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (214 aa)
CCO24214.1Chloramphenicol acetyltransferase. (233 aa)
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (513 aa)
gcpPutative tRNA threonylcarbamoyladenosine biosynthesis protein Gcp; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (355 aa)
fabIEnoyl-[acyl-carrier-protein] reductase [NADH]; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (254 aa)
CCO24585.1Ribosomal-protein-alanine acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (154 aa)
pta-2Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (705 aa)
CCO25060.1Acetyltransferase, GNAT family. (132 aa)
ptbPhosphate butyryltransferase. (326 aa)
plsYGlycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (194 aa)
bioFPutative 8-amino-7-oxononanoate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (391 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (345 aa)
fabZ(3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (154 aa)
lpxAAcyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (265 aa)
Your Current Organism:
Desulfovibrio hydrothermalis
NCBI taxonomy Id: 1121451
Other names: D. hydrothermalis AM13 = DSM 14728, Desulfovibrio hydrothermalis AM13, Desulfovibrio hydrothermalis AM13 = DSM 14728, Desulfovibrio hydrothermalis DSM 14728, Desulfovibrio hydrothermalis DSM 14728 = AM13
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