Your Input: | |
| | ptb | Phosphate butyryltransferase. (326 aa) |
| | CCO25080.1 | Putative DNA polymerase III, delta prime subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (288 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa) |
| | CCO25084.1 | IMP cyclohydrolase. (424 aa) |
| | thiC | Phosphomethylpyrimidine synthase. (421 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (230 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ALAD family. (327 aa) |
| | CCO25202.1 | Putative transcriptional regulator, AsnC family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (154 aa) |
| | CCO25217.1 | Phosphoribulokinase. (308 aa) |
| | rpoA | RNA polymerase (alpha subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (346 aa) |
| | rpoC | RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1385 aa) |
| | rpoB | RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1367 aa) |
| | nusG | Transcription termination factor; Participates in transcription elongation, termination and antitermination. (186 aa) |
| | CCO25290.1 | IMP cyclohydrolase. (199 aa) |
| | fliI | Flagellar-specific ATPase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (437 aa) |
| | CCO25330.1 | Homologs of previously reported genes of unknown function. (218 aa) |
| | prs | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (312 aa) |
| | rho | Transcriptional terminator Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (424 aa) |
| | CCO25407.1 | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. (327 aa) |
| | purU | Formyltetrahydrofolate hydrolase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (289 aa) |
| | CCO25436.1 | Cobalbumin biosynthesis protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (168 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (889 aa) |
| | CCO22006.1 | Homologs of previously reported genes of unknown function. (596 aa) |
| | cas1 | Putative RNA-directed DNA polymerase; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (875 aa) |
| | cbiC | Cobalt-precorrin-8X methylmutase. (225 aa) |
| | nadD | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (218 aa) |
| | guaB | Inosine-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa) |
| | guaA | GMP synthetase; Catalyzes the synthesis of GMP from XMP. (515 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (183 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (175 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (350 aa) |
| | nadE | Putative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (549 aa) |
| | CCO22140.1 | Adenylate/guanylate cyclase with Chase sensor. (786 aa) |
| | accC | Pyruvate carboxylase; Function of strongly homologous gene; enzyme. (472 aa) |
| | accD | Acetyl-CoA carboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (750 aa) |
| | CCO22300.1 | Protein of unknown function; No homology to any previously reported sequences. (447 aa) |
| | CCO22310.1 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (301 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (362 aa) |
| | CCO22387.1 | DAHP synthetase I/KDSA. (363 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (464 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (992 aa) |
| | cbiH | Cobalt-precorrin-3B C(17)-methyltransferase. (279 aa) |
| | CCO22437.1 | Cobalamin (Vitamin B12) biosynthesis CbiG protein. (341 aa) |
| | hemL | Glutamate-1-semialdehyde 2,1-aminotransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (422 aa) |
| | CCO22439.1 | Putative transcriptional regulator, AsnC family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (161 aa) |
| | dxs | 1-deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa) |
| | pta | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (704 aa) |
| | CCO22488.1 | Putative adenylate cyclase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (1305 aa) |
| | CCO22489.1 | Homologs of previously reported genes of unknown function. (414 aa) |
| | nusB | N utilization substance protein B homolog; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (187 aa) |
| | CCO22547.1 | DNA polymerase III delta. (329 aa) |
| | hemC | Porphobilinogen deaminase (hydroxymethylbilane synthase); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (309 aa) |
| | cobT | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (363 aa) |
| | CCO22615.1 | Homologs of previously reported genes of unknown function. (165 aa) |
| | dnaE | DNA polymerase III subunit alpha. (1174 aa) |
| | CCO22650.1 | Homologs of previously reported genes of unknown function. (128 aa) |
| | CCO22652.1 | Putative anti-sigma regulatory factor, serine/threonine protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (143 aa) |
| | CCO22664.1 | Homologs of previously reported genes of unknown function. (269 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (425 aa) |
| | CCO22679.1 | CinA domain protein; Belongs to the CinA family. (159 aa) |
| | mop | Aldehyde oxidoreductase; Function experimentally demonstrated in the studied genus; enzyme. (905 aa) |
| | CCO22735.1 | Homologs of previously reported genes of unknown function. (389 aa) |
| | cobB | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (460 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (389 aa) |
| | cbiD | Putative cobalt-precorrin-6A synthase [deacetylating]; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (366 aa) |
| | CCO22756.1 | Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit. (406 aa) |
| | cbiF | Cobalt-precorrin-4 C(11)-methyltransferase. (252 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (224 aa) |
| | CCO22766.1 | Uroporphyrin-III C-methyltransferase. (504 aa) |
| | CCO22835.1 | 5-enolpyruvylshikimate-3-phosphate synthase-like protein. (548 aa) |
| | CCO22840.1 | Metal dependent phosphohydrolase. (205 aa) |
| | cmk | Cytidylate kinase. (222 aa) |
| | Acsm3 | Acyl-coenzyme A synthetase ACSM3, mitochondrial; Function of strongly homologous gene; putative enzyme. (548 aa) |
| | queH | Conserved protein of unknown function; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (181 aa) |
| | CCO22871.1 | Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (398 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (627 aa) |
| | pyrB | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (308 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (423 aa) |
| | capI | Protein CapI. (335 aa) |
| | coaBC | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa) |
| | queA | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (361 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa) |
| | CCO23072.1 | DNA polymerase III, beta subunit. (387 aa) |
| | atpB | ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (228 aa) |
| | atpE-2 | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (107 aa) |
| | CCO23124.1 | 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (191 aa) |
| | CCO23143.1 | Conserved membrane protein of unknown function; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (226 aa) |
| | cobS | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (251 aa) |
| | acs | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (658 aa) |
| | rpoH | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (322 aa) |
| | hpt | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (174 aa) |
| | CCO23232.1 | dTDP-glucose 4,6-dehydratase. (332 aa) |
| | CCO23238.1 | NAD-dependent epimerase/dehydratase. (319 aa) |
| | cobDQ | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (880 aa) |
| | CCO23317.1 | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog. (278 aa) |
| | CCO23328.1 | Amine oxidase, flavin-containing. (449 aa) |
| | CCO23339.1 | H+transporting two-sector ATPase B/B' subunit; Belongs to the ATPase B chain family. (138 aa) |
| | atpF | ATP synthase subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (185 aa) |
| | atpH | ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (183 aa) |
| | atpA | ATP synthase (subunit alpha, component F1); Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (502 aa) |
| | atpG | ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (292 aa) |
| | atpD | ATP synthase (subunit beta, component F1); Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (467 aa) |
| | atpC | ATP synthase (subunit epsilon, F1 subunit); Produces ATP from ADP in the presence of a proton gradient across the membrane. (142 aa) |
| | glmU | Fused N-acetyl glucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (460 aa) |
| | purD | Phosphoribosylglycinamide synthetase phosphoribosylamine-glycine ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GARS family. (423 aa) |
| | purE | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (164 aa) |
| | coaX | Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (261 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa) |
| | CCO23395.1 | Uncharacterized 15.0 kDa protein in dhaT-dhaS intergenic region. (134 aa) |
| | CCO23447.1 | Cytidyltransferase-related domain protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (510 aa) |
| | CCO23466.1 | Conserved membrane protein of unknown function; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (212 aa) |
| | queF | NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (167 aa) |
| | purB | Adenylosuccinate lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) |
| | CCO23546.1 | Homologs of previously reported genes of unknown function. (173 aa) |
| | thyX | Thymidylate synthase thyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (247 aa) |
| | CCO23571.1 | DRTGG domain protein. (354 aa) |
| | CCO23577.1 | Adenosine/AMP deaminase. (498 aa) |
| | CCO23595.1 | Phosphoribosylglycinamide synthetase. (410 aa) |
| | CCO23600.1 | Putative dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (285 aa) |
| | CCO23603.1 | Oxidoreductase FAD/NAD(P)-binding domain protein. (276 aa) |
| | hldD | ADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (325 aa) |
| | trpB | Tryptophan synthase (beta subunit); The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (403 aa) |
| | mosB | Molybdenum storage protein subunit beta. (282 aa) |
| | purM | Phosphoribosylaminoimidazole synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (348 aa) |
| | CCO23819.1 | Homologs of previously reported genes of unknown function. (330 aa) |
| | CCO23826.1 | 3-dehydroquinate synthase homolog. (327 aa) |
| | pheA | P-protein [Includes: Chorismate mutase; Prephenate dehydratase]. (367 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (444 aa) |
| | CCO23829.1 | Prephenate dehydrogenase. (262 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (329 aa) |
| | CCO23833.1 | Indole-3-glycerol-phosphate synthase. (259 aa) |
| | trpF | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (212 aa) |
| | trpB-2 | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (392 aa) |
| | trpA | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (255 aa) |
| | CCO23851.1 | DRTGG domain protein. (355 aa) |
| | folE | GTP cyclohydrolase folE2; Converts GTP to 7,8-dihydroneopterin triphosphate. (255 aa) |
| | acs-2 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (661 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (210 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (230 aa) |
| | CCO23917.1 | Anaerobic cobalt chelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. (265 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase; Belongs to the PdxA family. (327 aa) |
| | carA | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (374 aa) |
| | kdsB | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (247 aa) |
| | CCO23968.1 | Homologs of previously reported genes of unknown function. (65 aa) |
| | nusA | NusA antitermination factor; Participates in both transcription termination and antitermination. (481 aa) |
| | ppnK | Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (283 aa) |
| | CCO24042.1 | Homologs of previously reported genes of unknown function. (774 aa) |
| | CCO24049.1 | Response regulator receiver protein. (276 aa) |
| | thiE | Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (216 aa) |
| | CCO24136.1 | Thiazole biosynthesis protein ThiH. (369 aa) |
| | thiG | Hydroxyethylthiazole phosphate synthetase (thiamine biosynthesis); Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (258 aa) |
| | CCO24138.1 | Thiamine biosynthesis protein ThiS. (66 aa) |
| | coaE | Pseudouridine synthase, RluA family; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (549 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa) |
| | cbiKp | Sirohydrochlorin cobaltochelatase CbiKP; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. (300 aa) |
| | CCO24205.1 | Precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. (237 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase 1. (269 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (544 aa) |
| | rpoN | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (471 aa) |
| | mtap | S-methyl-5'-thioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (249 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (591 aa) |
| | rpoD | RNA polymerase, sigma 70 (sigma D) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (585 aa) |
| | cobD | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (316 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (157 aa) |
| | CCO24323.1 | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (294 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (231 aa) |
| | pyrC-2 | Dihydro-orotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (347 aa) |
| | CCO24355.1 | Oxidoreductase FAD-binding domain protein. (264 aa) |
| | pyrD | Dihydroorotate dehydrogenase (catalytic subunit); Catalyzes the conversion of dihydroorotate to orotate. (304 aa) |
| | CCO24451.1 | Protein of unknown function; No homology to any previously reported sequences. (501 aa) |
| | CCO24455.1 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (280 aa) |
| | ybbP | Putative enzyme with DAC domain protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (248 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (780 aa) |
| | CCO24467.1 | 4Fe-4S ferredoxin iron-sulfur binding domain protein (fragment). (180 aa) |
| | CCO24481.1 | 1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase. (251 aa) |
| | dnaC | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (474 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (300 aa) |
| | purT | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (393 aa) |
| | CCO24524.1 | Beta-lactamase domain protein. (280 aa) |
| | pdxJ | Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (241 aa) |
| | udg | UDP-glucose 6-dehydrogenase. (448 aa) |
| | CCO24546.1 | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (531 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (340 aa) |
| | nadC | Nicotinate-nucleotide pyrophosphorylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NadC/ModD family. (290 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (223 aa) |
| | hemA | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (441 aa) |
| | CCO24555.1 | Siroheme synthase. (225 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase. (148 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa) |
| | aroQ | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (151 aa) |
| | CCO24689.1 | Phosphomethylpyrimidine kinase. (454 aa) |
| | PUR | Amidophosphoribosyltransferase, chloroplastic; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (463 aa) |
| | pyrAB | Pyrimidine-specific carbamoyl-phosphate synthetase (large subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family. (1077 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (416 aa) |
| | selA | Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (467 aa) |
| | CCO24754.1 | FolC bifunctional protein. (384 aa) |
| | CCO24764.1 | H+transporting two-sector ATPase gamma subunit. (286 aa) |
| | atpA-2 | ATP synthase (subunit alpha, component F1); Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (508 aa) |
| | atpF-2 | H+transporting two-sector ATPase B/B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (244 aa) |
| | atpE | ATP synthase subunit c 2; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (92 aa) |
| | atpB-2 | ATP synthase subunit a 2; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (223 aa) |
| | CCO24771.1 | ATP synthase F1, epsilon subunit. (126 aa) |
| | atpD-2 | ATP synthase (subunit beta, component F1); Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (469 aa) |
| | umuC | DNA polymerase V, subunit C; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (436 aa) |
| | accC-2 | Pyruvate carboxylase; Function of strongly homologous gene; enzyme. (472 aa) |
| | CCO24793.1 | Acetyl-CoA carboxylase. (752 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (324 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (167 aa) |
| | dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (661 aa) |
| | gpt | Guanine-hypoxanthine phosphoribosyltransferase (modular protein); Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (208 aa) |
| | tgt | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (378 aa) |
| | ackA | Acetate kinase A and propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa) |
| | pta-2 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (705 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (73 aa) |
| | CCO24958.1 | RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (263 aa) |
| | CCO25033.1 | Biotin and thiamin synthesis associated. (476 aa) |
| | CCO25037.1 | Putative cytoplasmic protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (522 aa) |
| | CCO25059.1 | NAD-dependent epimerase/dehydratase. (315 aa) |
