STRINGSTRING
ogt ogt xseA xseA xseB xseB CCO22425.1 CCO22425.1 CCO22340.1 CCO22340.1 lexA lexA CCO22331.1 CCO22331.1 CCO22330.1 CCO22330.1 CCO22329.1 CCO22329.1 CCO22317.1 CCO22317.1 CCO22315.1 CCO22315.1 CCO22314.1 CCO22314.1 CCO22302.1 CCO22302.1 CCO22301.1 CCO22301.1 CCO22298.1 CCO22298.1 CCO22296.1 CCO22296.1 CCO22280.1 CCO22280.1 CCO22275.1 CCO22275.1 CCO22273.1 CCO22273.1 hsdBM hsdBM hsdBR hsdBR CCO22262.1 CCO22262.1 CCO22256.1 CCO22256.1 CCO22248.1 CCO22248.1 CCO22238.1 CCO22238.1 CCO22237.1 CCO22237.1 CCO22203.1 CCO22203.1 CCO22202.1 CCO22202.1 CCO22162.1 CCO22162.1 lysS lysS CCO22025.1 CCO22025.1 cas2 cas2 cas1 cas1 lcrS lcrS CCO22012.1 CCO22012.1 CCO22011.1 CCO22011.1 CCO22006.1 CCO22006.1 CCO22004.1 CCO22004.1 CCO21998.1 CCO21998.1 CCO21990.1 CCO21990.1 proS proS CCO22458.1 CCO22458.1 CCO22487.1 CCO22487.1 mraW mraW gltX gltX nusB nusB leuS leuS CCO22547.1 CCO22547.1 CCO22579.1 CCO22579.1 insF insF CCO22604.1 CCO22604.1 CCO22605.1 CCO22605.1 rimO rimO CCO22644.1 CCO22644.1 dnaE dnaE dtd dtd CCO22652.1 CCO22652.1 cysS cysS serS serS CCO22694.1 CCO22694.1 CCO22709.1 CCO22709.1 exoA exoA trmJ trmJ dinB dinB valS valS yraL yraL CCO22787.1 CCO22787.1 rnhB rnhB trmD trmD rimM rimM truA truA rnhA rnhA CCO22857.1 CCO22857.1 fmt fmt aspS aspS hisS hisS CCO22865.1 CCO22865.1 CCO22866.1 CCO22866.1 CCO22867.1 CCO22867.1 queH queH CCO22886.1 CCO22886.1 rlmN rlmN CCO22952.1 CCO22952.1 CCO22964.1 CCO22964.1 CCO22965.1 CCO22965.1 mutM mutM CCO22999.1 CCO22999.1 CCO23030.1 CCO23030.1 topA topA gyrA gyrA gyrB gyrB CCO23072.1 CCO23072.1 CCO23073.1 CCO23073.1 CCO23087.1 CCO23087.1 CCO23104.1 CCO23104.1 ihfA ihfA rsmG rsmG rlmH rlmH argS argS CCO23153.1 CCO23153.1 CCO23178.1 CCO23178.1 rpoH rpoH radA radA lcrS-2 lcrS-2 CCO23201.1 CCO23201.1 ytqB ytqB CCO23285.1 CCO23285.1 CCO23287.1 CCO23287.1 CCO23302.1 CCO23302.1 rny rny tyrS tyrS uvrA uvrA rbpE rbpE CCO23479.1 CCO23479.1 rluA rluA CCO23497.1 CCO23497.1 CCO23502.1 CCO23502.1 CCO23507.1 CCO23507.1 dnaA dnaA CCO23565.1 CCO23565.1 mutL mutL CCO23622.1 CCO23622.1 CCO23655.1 CCO23655.1 glnS glnS FCA FCA xerC xerC CCO23730.1 CCO23730.1 CCO23731.1 CCO23731.1 alaS alaS recA recA rnr rnr nfo nfo CCO23807.1 CCO23807.1 CCO23818.1 CCO23818.1 rnc rnc CCO23903.1 CCO23903.1 CCO23905.1 CCO23905.1 CCO23910.1 CCO23910.1 trmH trmH CCO23923.1 CCO23923.1 CCO23936.1 CCO23936.1 dsvC dsvC trpS trpS CCO23969.1 CCO23969.1 pnpA pnpA truB truB CCO23974.1 CCO23974.1 rbfA rbfA nusA nusA csrA csrA CCO24003.1 CCO24003.1 CCO24012.1 CCO24012.1 CCO24028.1 CCO24028.1 CCO24038.1 CCO24038.1 CCO24042.1 CCO24042.1 CCO24052.1 CCO24052.1 codV codV CCO24080.1 CCO24080.1 CCO24081.1 CCO24081.1 CCO24084.1 CCO24084.1 asnS asnS hcpC hcpC coaE coaE mnmA mnmA CCO24211.1 CCO24211.1 CCO24213.1 CCO24213.1 CCO24235.1 CCO24235.1 tadA tadA rpoN rpoN trmFO trmFO trmF trmF rsmA rsmA mutS mutS dnaG dnaG rpoD rpoD CCO24305.1 CCO24305.1 CCO24311.1 CCO24311.1 trmL trmL gcp gcp CCO24423.1 CCO24423.1 CCO24442.1 CCO24442.1 CCO24447.1 CCO24447.1 CCO24451.1 CCO24451.1 priA priA CCO24463.1 CCO24463.1 CCO24467.1 CCO24467.1 CCO24472.1 CCO24472.1 tlyA tlyA dnaC dnaC uvrC uvrC ileS ileS CCO24527.1 CCO24527.1 mfd mfd recO recO glyQ glyQ glyS glyS tilS tilS CCO24561.1 CCO24561.1 CCO24562.1 CCO24562.1 mutS-2 mutS-2 CCO24569.1 CCO24569.1 xerD xerD CCO24581.1 CCO24581.1 rtcB rtcB ligA ligA uvrB uvrB CCO24624.1 CCO24624.1 CCO24635.1 CCO24635.1 CCO24636.1 CCO24636.1 CCO24650.1 CCO24650.1 CCO24658.1 CCO24658.1 CCO24664.1 CCO24664.1 CCO24665.1 CCO24665.1 CCO24673.1 CCO24673.1 ybeY ybeY CCO24684.1 CCO24684.1 CCO24719.1 CCO24719.1 metG metG selA selA recQ recQ CCO24788.1 CCO24788.1 umuD umuD umuC umuC rbpE-2 rbpE-2 miaA miaA CCO24818.1 CCO24818.1 CCO24819.1 CCO24819.1 recD recD recR recR dnaX dnaX CCO24883.1 CCO24883.1 miaB miaB CCO24891.1 CCO24891.1 nth nth tgt tgt CCO24904.1 CCO24904.1 CCO24912.1 CCO24912.1 dnaJ dnaJ rpoZ rpoZ CCO24951.1 CCO24951.1 CCO24958.1 CCO24958.1 dsvC-2 dsvC-2 CCO24996.1 CCO24996.1 CCO24997.1 CCO24997.1 CCO25080.1 CCO25080.1 CCO25085.1 CCO25085.1 thrS thrS pheS pheS pheT pheT CCO25169.1 CCO25169.1 rnj rnj CCO25190.1 CCO25190.1 rpoA rpoA rpoC rpoC rpoB rpoB nusG nusG CCO25279.1 CCO25279.1 CCO25323.1 CCO25323.1 mnmE mnmE CCO25355.1 CCO25355.1 CCO25373.1 CCO25373.1 ruvB ruvB ruvA ruvA ruvC ruvC rlmE rlmE rho rho CCO25427.1 CCO25427.1 polA polA CCO25435.1 CCO25435.1 CCO25439.1 CCO25439.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ogtMethylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (168 aa)
xseAExodeoxyribonuclease 7 large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (456 aa)
xseBExodeoxyribonuclease 7 small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (80 aa)
CCO22425.1Glycosyl transferase group 1. (810 aa)
CCO22340.1SMC domain protein; May be involved in recombinational repair of damaged DNA. (519 aa)
lexALexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (207 aa)
CCO22331.1Bacteriophage-related protein (fragment). (95 aa)
CCO22330.1Bacteriophage-related protein (fragment). (51 aa)
CCO22329.1Resolvase domain-containing protein (modular protein). (638 aa)
CCO22317.1Putative type I restriction-modification system (N6 DNA methylase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (710 aa)
CCO22315.1Homologs of previously reported genes of unknown function. (463 aa)
CCO22314.1Putative type-1 restriction system, restriction subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (989 aa)
CCO22302.1Putative UvrABC system protein A; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (752 aa)
CCO22301.1Protein of unknown function; No homology to any previously reported sequences. (388 aa)
CCO22298.1Putative Elongator protein 3/MiaB/NifB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (394 aa)
CCO22296.1Protein of unknown function; No homology to any previously reported sequences. (395 aa)
CCO22280.1Protein of unknown function; No homology to any previously reported sequences; Belongs to the 'phage' integrase family. (345 aa)
CCO22275.1Homologs of previously reported genes of unknown function. (56 aa)
CCO22273.1Protein of unknown function; No homology to any previously reported sequences. (68 aa)
hsdBMModification methylase BsuBI. (511 aa)
hsdBRType-2 restriction enzyme BsuBI. (319 aa)
CCO22262.1Protein of unknown function; No homology to any previously reported sequences. (257 aa)
CCO22256.1Protein of unknown function; No homology to any previously reported sequences. (1689 aa)
CCO22248.1O-methyltransferase family 2. (556 aa)
CCO22238.1Transposase. (107 aa)
CCO22237.1Protein of unknown function; No homology to any previously reported sequences. (73 aa)
CCO22203.1Phage transposition protein B. (242 aa)
CCO22202.1Transposase. (712 aa)
CCO22162.1Single-stranded DNA-binding protein. (191 aa)
lysSlysyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. (531 aa)
CCO22025.1Protein of unknown function; No homology to any previously reported sequences. (677 aa)
cas2Protein of unknown function; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (94 aa)
cas1Putative RNA-directed DNA polymerase; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (875 aa)
lcrSLow calcium response locus protein S. (88 aa)
CCO22012.1Integrase catalytic region. (266 aa)
CCO22011.1Integrase core domain protein (fragment). (139 aa)
CCO22006.1Homologs of previously reported genes of unknown function. (596 aa)
CCO22004.1DNA topoisomerase (fragment). (322 aa)
CCO21998.1Putative phage integrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 'phage' integrase family. (395 aa)
CCO21990.1Relaxase/mobilization nuclease family protein (fragment). (325 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (581 aa)
CCO22458.1Uracil-DNA glycosylase. (239 aa)
CCO22487.1RNA methyltransferase, TrmA family; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (465 aa)
mraWS-adenosyl-dependent methyltransferase active on membrane-located substrates; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (325 aa)
gltXGlutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (464 aa)
nusBN utilization substance protein B homolog; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (187 aa)
leuSLeucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (831 aa)
CCO22547.1DNA polymerase III delta. (329 aa)
CCO22579.1Integrase catalytic region (fragment). (195 aa)
insFFragment of IS3 element protein InsF (part 2); Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin. (103 aa)
CCO22604.1Transposase. (92 aa)
CCO22605.1Protein of unknown function; No homology to any previously reported sequences. (145 aa)
rimORibosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (437 aa)
CCO22644.1Integrase core domain-containing protein. (352 aa)
dnaEDNA polymerase III subunit alpha. (1174 aa)
dtdD-Tyr-tRNATyr deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (155 aa)
CCO22652.1Putative anti-sigma regulatory factor, serine/threonine protein kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (143 aa)
cysScysteinyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (485 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (425 aa)
CCO22694.1Homologs of previously reported genes of unknown function. (260 aa)
CCO22709.1TOBE domain protein. (359 aa)
exoAExodeoxyribonuclease. (255 aa)
trmJRNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (246 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (389 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (883 aa)
yraLPutative methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (280 aa)
CCO22787.1Homologs of previously reported genes of unknown function; Belongs to the UPF0102 family. (136 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (218 aa)
trmDtRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (436 aa)
rimMRibosome maturation factor rimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (178 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (276 aa)
rnhARibonuclease HI, degrades RNA of DNA-RNA hybrids; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (154 aa)
CCO22857.1NusB/RsmB/TIM44; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (427 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (318 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (607 aa)
hisShistidyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (412 aa)
CCO22865.1tRNA (Adenine-N(1)-)-methyltransferase. (330 aa)
CCO22866.1Radical SAM domain protein. (328 aa)
CCO22867.1Ribonuclease, Rne/Rng family; Function of strongly homologous gene; enzyme. (479 aa)
queHConserved protein of unknown function; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (181 aa)
CCO22886.13'-5' exonuclease. (198 aa)
rlmNRibosomal RNA large subunit methyltransferase N; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (345 aa)
CCO22952.1PHP domain protein. (285 aa)
CCO22964.1Homologs of previously reported genes of unknown function. (318 aa)
CCO22965.1ATPase involved in DNA repair-like protein. (447 aa)
mutMFormamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (274 aa)
CCO22999.1Metal dependent phosphohydrolase. (444 aa)
CCO23030.1RNA methyltransferase, TrmH family, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (251 aa)
topADNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (800 aa)
gyrADNA gyrase (subunit A); A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (820 aa)
gyrBDNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (796 aa)
CCO23072.1DNA polymerase III, beta subunit. (387 aa)
CCO23073.1Chromosomal replication initiator protein dnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (434 aa)
CCO23087.1Homologs of previously reported genes of unknown function. (89 aa)
CCO23104.1Radical SAM domain protein. (347 aa)
ihfAIntegration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (100 aa)
rsmGRibosomal RNA small subunit methyltransferase G; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (229 aa)
rlmHRibosomal RNA large subunit methyltransferase H; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (156 aa)
argSArginine--tRNA ligase. (547 aa)
CCO23153.1DEAD/DEAH box helicase domain protein. (939 aa)
CCO23178.1Homologs of previously reported genes of unknown function. (262 aa)
rpoHRNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (322 aa)
radADNA repair protein RadA homolog; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (439 aa)
lcrS-2Low calcium response locus protein S. (88 aa)
CCO23201.1Homologs of previously reported genes of unknown function. (192 aa)
ytqBPutative rRNA methylase ytqB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (190 aa)
CCO23285.1Integrase catalytic region (fragment). (73 aa)
CCO23287.1Anaerobic ribonucleoside-triphosphate reductase. (687 aa)
CCO23302.1Hydrolase, TatD family. (276 aa)
rnyEndoribonuclease Y; Endoribonuclease that initiates mRNA decay. (518 aa)
tyrSTyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (423 aa)
uvrAExcinuclease ABC (subunit A); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (915 aa)
rbpEPutative RNA-binding protein rbpE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (87 aa)
CCO23479.1Homologs of previously reported genes of unknown function. (253 aa)
rluARibosomal large subunit pseudouridine synthase A. (214 aa)
CCO23497.1Methylated-DNA-(Protein)-cysteine S-methyltransferase DNA binding. (103 aa)
CCO23502.1Fmu (Sun) domain protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (418 aa)
CCO23507.1Pseudouridine synthase; Belongs to the pseudouridine synthase RluA family. (290 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (460 aa)
CCO23565.1Homologs of previously reported genes of unknown function. (232 aa)
mutLDNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (640 aa)
CCO23622.1Homologs of previously reported genes of unknown function. (103 aa)
CCO23655.1Ribonucleoside-diphosphate reductase. (894 aa)
glnSglutamyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (565 aa)
FCACytosine deaminase. (148 aa)
xerCTyrosine recombinase XerC; Belongs to the 'phage' integrase family. (307 aa)
CCO23730.1Homologs of previously reported genes of unknown function. (280 aa)
CCO23731.1Homologs of previously reported genes of unknown function. (255 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (880 aa)
recAMultifunctional SOS repair factor; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (351 aa)
rnrRibonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (748 aa)
nfoPutative endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (283 aa)
CCO23807.1Homologs of previously reported genes of unknown function. (380 aa)
CCO23818.1RNP-1 like RNA-binding protein. (87 aa)
rncRibonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (237 aa)
CCO23903.1MiaB-like tRNA modifying enzyme. (431 aa)
CCO23905.1Homologs of previously reported genes of unknown function. (293 aa)
CCO23910.1Single-stranded-DNA-specific exonuclease RecJ. (577 aa)
trmHtRNA guanosine-2'-O-methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (196 aa)
CCO23923.1Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family. (227 aa)
CCO23936.1Metal dependent phophohydrolase. (219 aa)
dsvCSulfite reductase, dissimilatory-type subunit gamma. (105 aa)
trpSTryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (331 aa)
CCO23969.1PP-loop domain protein; Belongs to the TtcA family. (307 aa)
pnpAPolynucleotide phosphorylase (PNPase); Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (742 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (311 aa)
CCO23974.1Phosphoesterase RecJ domain protein. (321 aa)
rbfARibosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (117 aa)
nusANusA antitermination factor; Participates in both transcription termination and antitermination. (481 aa)
csrACarbon storage regulator homolog; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (79 aa)
CCO24003.1Integrase family protein; Belongs to the 'phage' integrase family. (397 aa)
CCO24012.1Conjugal transfer TrbD family protein. (99 aa)
CCO24028.1Type II secretion system protein E. (326 aa)
CCO24038.1DNA topoisomerase type IA central domain protein. (723 aa)
CCO24042.1Homologs of previously reported genes of unknown function. (774 aa)
CCO24052.1Relaxase/mobilization nuclease family protein (fragment). (331 aa)
codVSite-specific tyrosine recombinase for chromosome partitioning; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (318 aa)
CCO24080.1Homologs of previously reported genes of unknown function. (968 aa)
CCO24081.1Exodeoxyribonuclease V; Belongs to the helicase family. UvrD subfamily. (1059 aa)
CCO24084.1Pseudouridine synthase; Belongs to the pseudouridine synthase RluA family. (282 aa)
asnSAsparaginyl tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (463 aa)
hcpCMajor exported protein. (160 aa)
coaEPseudouridine synthase, RluA family; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (549 aa)
mnmAtRNA-specific 2-thiouridylase mnmA. (362 aa)
CCO24211.1NUDIX hydrolase; Belongs to the Nudix hydrolase family. (137 aa)
CCO24213.1Excinuclease ABC C subunit domain protein (modular protein). (115 aa)
CCO24235.1Homologs of previously reported genes of unknown function. (269 aa)
tadAtRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (170 aa)
rpoNRNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (471 aa)
trmFOMethylenetetrahydrofolate--tRNA-(uracil-5-)- methyltransferase TrmFO; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (439 aa)
trmFtRNA uridine 5-carboxymethylaminomethyl modification enzyme; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (627 aa)
rsmARibosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (262 aa)
mutSMutS2 protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (788 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (591 aa)
rpoDRNA polymerase, sigma 70 (sigma D) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (585 aa)
CCO24305.1Homologs of previously reported genes of unknown function. (217 aa)
CCO24311.1Nuclease (SNase domain protein). (208 aa)
trmLtRNA (cytidine(34)-2'-O)-methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (161 aa)
gcpPutative tRNA threonylcarbamoyladenosine biosynthesis protein Gcp; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (355 aa)
CCO24423.1Homologs of previously reported genes of unknown function. (243 aa)
CCO24442.1CRISPR-associated protein family protein. (188 aa)
CCO24447.1Homologs of previously reported genes of unknown function. (336 aa)
CCO24451.1Protein of unknown function; No homology to any previously reported sequences. (501 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (780 aa)
CCO24463.1Smr protein/MutS2. (248 aa)
CCO24467.14Fe-4S ferredoxin iron-sulfur binding domain protein (fragment). (180 aa)
CCO24472.1Polynucleotide adenylyltransferase region; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (391 aa)
tlyA16S/23S rRNA (cytidine-2'-O)-methyltransferase TlyA. (247 aa)
dnaCReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (474 aa)
uvrCUvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (600 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (938 aa)
CCO24527.1Homologs of previously reported genes of unknown function. (164 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1149 aa)
recODNA repair protein recO; Involved in DNA repair and RecF pathway recombination. (246 aa)
glyQglycyl-tRNA synthetase (alpha subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (290 aa)
glySGlycine--tRNA ligase beta subunit. (697 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (353 aa)
CCO24561.1AAA ATPase central domain protein. (420 aa)
CCO24562.1Conserved protein of unknown function; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (243 aa)
mutS-2DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (886 aa)
CCO24569.1Polynucleotide adenylyltransferase region; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (891 aa)
xerDTyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (304 aa)
CCO24581.1Putative Micrococcal nuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (169 aa)
rtcBtRNA-splicing ligase RtcB; Belongs to the RtcB family. (475 aa)
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (615 aa)
uvrBExcinuclease ABC (subunit B); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociat [...] (668 aa)
CCO24624.1Metal dependent phosphohydrolase. (345 aa)
CCO24635.1SirA family protein; Belongs to the sulfur carrier protein TusA family. (204 aa)
CCO24636.1RNA-binding S4 domain protein; Belongs to the pseudouridine synthase RsuA family. (250 aa)
CCO24650.1Homologs of previously reported genes of unknown function. (454 aa)
CCO24658.1Transposase. (323 aa)
CCO24664.1Protein of unknown function; No homology to any previously reported sequences. (95 aa)
CCO24665.1Protein of unknown function; No homology to any previously reported sequences. (243 aa)
CCO24673.1Homologs of previously reported genes of unknown function. (182 aa)
ybeYPutative rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (128 aa)
CCO24684.1Putative RNA methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the methyltransferase superfamily. (394 aa)
CCO24719.1Metal-dependent phosphohydrolase HD sub domain protein. (253 aa)
metGMethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (646 aa)
selASelenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (467 aa)
recQATP-dependent DNA helicase recQ. (742 aa)
CCO24788.1Homologs of previously reported genes of unknown function. (304 aa)
umuDDNA polymerase V, subunit D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S24 family. (145 aa)
umuCDNA polymerase V, subunit C; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (436 aa)
rbpE-2Putative RNA-binding protein rbpE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (88 aa)
miaAtRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (310 aa)
CCO24818.1Methyltransferase. (186 aa)
CCO24819.1Beta-lactamase domain protein. (535 aa)
recDHelicase, RecD/TraA family; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (731 aa)
recRRecombination protein recR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (201 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (661 aa)
CCO24883.1Homologs of previously reported genes of unknown function. (159 aa)
miaB(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (473 aa)
CCO24891.1Homologs of previously reported genes of unknown function. (95 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (220 aa)
tgttRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (378 aa)
CCO24904.1Heat shock protein DnaJ domain protein. (269 aa)
CCO24912.1Threonyl/alanyl tRNA synthetase SAD. (145 aa)
dnaJChaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (369 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (73 aa)
CCO24951.1PP-loop domain protein. (249 aa)
CCO24958.1RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (263 aa)
dsvC-2Sulfite reductase, dissimilatory-type subunit gamma. (105 aa)
CCO24996.1Homologs of previously reported genes of unknown function. (205 aa)
CCO24997.1Homologs of previously reported genes of unknown function. (177 aa)
CCO25080.1Putative DNA polymerase III, delta prime subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (288 aa)
CCO25085.1Ribonuclease II. (687 aa)
thrSthreonyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. (642 aa)
pheSphenylalanyl-tRNA synthetase (alpha subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (349 aa)
pheTPhenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (799 aa)
CCO25169.1Radical SAM domain protein. (366 aa)
rnjBeta-lactamase domain protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (567 aa)
CCO25190.1Peptidase M22 glycoprotease. (269 aa)
rpoARNA polymerase (alpha subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (346 aa)
rpoCRNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1385 aa)
rpoBRNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1367 aa)
nusGTranscription termination factor; Participates in transcription elongation, termination and antitermination. (186 aa)
CCO25279.1tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (323 aa)
CCO25323.1Putative Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (135 aa)
mnmEtRNA modification GTPase MnmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (461 aa)
CCO25355.1Ribonuclease P protein component (fragment); RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (89 aa)
CCO25373.1Transposase. (290 aa)
ruvBHolliday junction DNA helicase, ATP-dependent component; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (326 aa)
ruvAHolliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (203 aa)
ruvCComponent of RuvABC resolvasome, endonuclease; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (168 aa)
rlmERibosomal RNA large subunit methyltransferase E; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (199 aa)
rhoTranscriptional terminator Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (424 aa)
CCO25427.1Anaerobic ribonucleoside-triphosphate reductase. (683 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (889 aa)
CCO25435.1Phosphoesterase RecJ domain protein. (331 aa)
CCO25439.1UvrD/REP helicase. (1033 aa)
Your Current Organism:
Desulfovibrio hydrothermalis
NCBI taxonomy Id: 1121451
Other names: D. hydrothermalis AM13 = DSM 14728, Desulfovibrio hydrothermalis AM13, Desulfovibrio hydrothermalis AM13 = DSM 14728, Desulfovibrio hydrothermalis DSM 14728, Desulfovibrio hydrothermalis DSM 14728 = AM13
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