STRINGSTRING
CCO25407.1 CCO25407.1 nadD nadD guaA guaA nadE nadE CCO22138.1 CCO22138.1 CCO22310.1 CCO22310.1 CCO22459.1 CCO22459.1 gltX gltX leuS leuS CCO22586.1 CCO22586.1 cysS cysS CCO22665.1 CCO22665.1 valS valS CCO22811.1 CCO22811.1 CCO22819.1 CCO22819.1 sat sat CCO22870.1 CCO22870.1 CCO22983.1 CCO22983.1 argS argS CCO23249.1 CCO23249.1 tyrS tyrS CCO23447.1 CCO23447.1 glnS glnS CCO23709.1 CCO23709.1 CCO23771.1 CCO23771.1 trpS trpS CCO23969.1 CCO23969.1 CCO24118.1 CCO24118.1 mnmA mnmA ileS ileS tilS tilS argG argG metG metG CCO24781.1 CCO24781.1 CCO24787.1 CCO24787.1 coaD coaD CCO24894.1 CCO24894.1 CCO24951.1 CCO24951.1 panC panC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
CCO25407.1Riboflavin biosynthesis protein RibF; Belongs to the ribF family. (327 aa)
nadDPutative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (218 aa)
guaAGMP synthetase; Catalyzes the synthesis of GMP from XMP. (515 aa)
nadEPutative glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (549 aa)
CCO22138.1Cysteine synthase. (764 aa)
CCO22310.1NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (301 aa)
CCO22459.1Phosphoadenosine phosphosulfate reductase. (286 aa)
gltXGlutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (464 aa)
leuSLeucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (831 aa)
CCO22586.1Asparagine synthase (Glutamine-hydrolyzing). (570 aa)
cysScysteinyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (485 aa)
CCO22665.1RfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (168 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (883 aa)
CCO22811.1UspA domain protein. (146 aa)
CCO22819.1Homologs of previously reported genes of unknown function. (252 aa)
satSulfate adenylyltransferase. (426 aa)
CCO22870.1UspA domain protein. (278 aa)
CCO22983.1Putative Asparagine synthetase [glutamine-hydrolyzing] 1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (614 aa)
argSArginine--tRNA ligase. (547 aa)
CCO23249.1Asparagine synthase (Glutamine-hydrolyzing). (651 aa)
tyrSTyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (423 aa)
CCO23447.1Cytidyltransferase-related domain protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (510 aa)
glnSglutamyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (565 aa)
CCO23709.1UspA domain protein. (297 aa)
CCO23771.1Homologs of previously reported genes of unknown function. (355 aa)
trpSTryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (331 aa)
CCO23969.1PP-loop domain protein; Belongs to the TtcA family. (307 aa)
CCO24118.1Protein of unknown function; No homology to any previously reported sequences. (147 aa)
mnmAtRNA-specific 2-thiouridylase mnmA. (362 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (938 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (353 aa)
argGArgininosuccinate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (410 aa)
metGMethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (646 aa)
CCO24781.1UspA domain protein. (164 aa)
CCO24787.1UspA domain protein. (140 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (167 aa)
CCO24894.1Homologs of previously reported genes of unknown function. (214 aa)
CCO24951.1PP-loop domain protein. (249 aa)
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (282 aa)
Your Current Organism:
Desulfovibrio hydrothermalis
NCBI taxonomy Id: 1121451
Other names: D. hydrothermalis AM13 = DSM 14728, Desulfovibrio hydrothermalis AM13, Desulfovibrio hydrothermalis AM13 = DSM 14728, Desulfovibrio hydrothermalis DSM 14728, Desulfovibrio hydrothermalis DSM 14728 = AM13
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