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dut dut gmk gmk SHK77191.1 SHK77191.1 pyrG pyrG SHL04441.1 SHL04441.1 ndk ndk tdk tdk SHL66184.1 SHL66184.1 SHL66274.1 SHL66274.1 SHL74161.1 SHL74161.1 thyA thyA
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query proteins and first shell of interactors
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second shell of interactors
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dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (194 aa)
SHK77191.1dCTP deaminase. (178 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (583 aa)
SHL04441.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (161 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
tdkThymidine kinase. (182 aa)
SHL66184.1Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (793 aa)
SHL66274.1Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (320 aa)
SHL74161.1Dihydrofolate synthase / folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (433 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
Your Current Organism:
Hymenobacter psychrotolerans
NCBI taxonomy Id: 1121959
Other names: H. psychrotolerans DSM 18569, Hymenobacter psychrotolerans DSM 18569, Hymenobacter psychrotolerans Tibet-IIU11, Hymenobacter sp. Tibet-IIU11
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