STRINGSTRING
SHL55548.1 SHL55548.1 nusA nusA dut dut SHK00071.1 SHK00071.1 nadK nadK atpG atpG atpA atpA atpH atpH atpF atpF atpE atpE atpB atpB polA polA SHK08490.1 SHK08490.1 queA queA SHK10276.1 SHK10276.1 kmo kmo kynU kynU SHK11888.1 SHK11888.1 coaE coaE SHK13165.1 SHK13165.1 SHK14816.1 SHK14816.1 coaX coaX pdhA pdhA SHK19680.1 SHK19680.1 SHK27449.1 SHK27449.1 SHK29022.1 SHK29022.1 gmk gmk nadD nadD pyrH pyrH nusG nusG rpoB rpoB rpoC rpoC rpoA rpoA SHK32454.1 SHK32454.1 guaB guaB SHK35116.1 SHK35116.1 SHK35356.1 SHK35356.1 SHK35459.1 SHK35459.1 queG queG SHK36641.1 SHK36641.1 SHK36795.1 SHK36795.1 SHK36833.1 SHK36833.1 SHK37009.1 SHK37009.1 accD accD SHK39863.1 SHK39863.1 queE queE folD folD SHK46067.1 SHK46067.1 dnaG dnaG SHK48770.1 SHK48770.1 SHK48804.1 SHK48804.1 SHK50778.1 SHK50778.1 SHK51729.1 SHK51729.1 murA murA SHK57209.1 SHK57209.1 rho rho SHK58011.1 SHK58011.1 comB comB queA-2 queA-2 priA priA ackA ackA SHK67025.1 SHK67025.1 kdsB kdsB accA accA guaA guaA SHK77191.1 SHK77191.1 SHK77310.1 SHK77310.1 SHK79915.1 SHK79915.1 SHK85916.1 SHK85916.1 SHK88437.1 SHK88437.1 SHK88730.1 SHK88730.1 SHK89258.1 SHK89258.1 SHK94144.1 SHK94144.1 SHK95028.1 SHK95028.1 pyrG pyrG SHK98426.1 SHK98426.1 purA purA SHL01243.1 SHL01243.1 SHL02477.1 SHL02477.1 SHL02515.1 SHL02515.1 SHL04095.1 SHL04095.1 SHL09346.1 SHL09346.1 SHL10344.1 SHL10344.1 SHL10802.1 SHL10802.1 SHL12784.1 SHL12784.1 coaD coaD SHL18533.1 SHL18533.1 SHL19030.1 SHL19030.1 SHL19335.1 SHL19335.1 ndk ndk tdk tdk purH purH SHL23162.1 SHL23162.1 pyrD pyrD SHL25183.1 SHL25183.1 SHL27028.1 SHL27028.1 SHL27549.1 SHL27549.1 SHL33429.1 SHL33429.1 SHL34085.1 SHL34085.1 dacA dacA SHL47097.1 SHL47097.1 SHL47387.1 SHL47387.1 SHL49272.1 SHL49272.1 purE purE carA carA dinB dinB SHL53632.1 SHL53632.1 fcl fcl SHL54292.1 SHL54292.1 SHL54586.1 SHL54586.1 adk adk SHL54756.1 SHL54756.1 SHL55472.1 SHL55472.1 SHL55513.1 SHL55513.1 SHL56875.1 SHL56875.1 SHL58460.1 SHL58460.1 SHL59037.1 SHL59037.1 SHL59638.1 SHL59638.1 SHL60012.1 SHL60012.1 purF purF purN purN SHL60204.1 SHL60204.1 purC purC SHL60338.1 SHL60338.1 purL purL pyrE pyrE SHL60478.1 SHL60478.1 SHL60522.1 SHL60522.1 SHL63108.1 SHL63108.1 SHL64552.1 SHL64552.1 SHL66184.1 SHL66184.1 SHL66274.1 SHL66274.1 nadE nadE SHL70207.1 SHL70207.1 tgt tgt SHL70614.1 SHL70614.1 atpD atpD SHL70707.1 SHL70707.1 SHL70745.1 SHL70745.1 SHL73004.1 SHL73004.1 SHL73776.1 SHL73776.1 SHL78731.1 SHL78731.1 dnaX dnaX SHL85157.1 SHL85157.1 SHL90914.1 SHL90914.1 SHL91603.1 SHL91603.1 SHL93834.1 SHL93834.1 SHL94712.1 SHL94712.1 SHL94888.1 SHL94888.1 SHL96173.1 SHL96173.1 thyA thyA SHM02538.1 SHM02538.1 SHM05005.1 SHM05005.1 SHM08129.1 SHM08129.1 SHM10069.1 SHM10069.1 SHM12368.1 SHM12368.1 SHM14216.1 SHM14216.1 SHM15660.1 SHM15660.1 cmk cmk SHM28678.1 SHM28678.1 SHM29968.1 SHM29968.1 SHM31928.1 SHM31928.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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SHL55548.1Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase. (216 aa)
nusANusA antitermination factor; Participates in both transcription termination and antitermination. (431 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa)
SHK00071.1RNA polymerase, sigma subunit, ECF family; Belongs to the sigma-70 factor family. ECF subfamily. (211 aa)
nadKNAD+ kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (297 aa)
atpGATP synthase F1 subcomplex gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (296 aa)
atpAF-type H+-transporting ATPase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (527 aa)
atpHF-type H+-transporting ATPase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (186 aa)
atpFATP synthase F0 subcomplex B subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (164 aa)
atpEATP synthase F0 subcomplex C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (85 aa)
atpBATP synthase F0 subcomplex A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (354 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (962 aa)
SHK08490.1RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (195 aa)
queAS-adenosylmethionine--tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (350 aa)
SHK10276.1RNA polymerase, sigma 54 subunit, RpoN/SigL. (529 aa)
kmoKynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily. (461 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (425 aa)
SHK11888.1UDP-2-acetamido-3-amino-2,3-dideoxy-glucuronate N-acetyltransferase. (197 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (198 aa)
SHK13165.1NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (394 aa)
SHK14816.1rfaE bifunctional protein, domain II; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (159 aa)
coaXType III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (247 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (395 aa)
SHK19680.1Hypothetical protein. (183 aa)
SHK27449.1RNA polymerase sigma-70 factor, ECF subfamily. (217 aa)
SHK29022.1RNA polymerase, sigma subunit, ECF family; Belongs to the sigma-70 factor family. ECF subfamily. (215 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (194 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (196 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa)
nusGTranscription antitermination protein nusG; Participates in transcription elongation, termination and antitermination. (188 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1300 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1450 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa)
SHK32454.1RNA polymerase sigma-70 factor, ECF subfamily. (188 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa)
SHK35116.1FRG domain-containing protein. (279 aa)
SHK35356.1Nicotinamide-nucleotide adenylyltransferase, NadR type. (177 aa)
SHK35459.1Predicted N-acyltransferase, GNAT family. (138 aa)
queGEpoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (310 aa)
SHK36641.1Uridine kinase; Belongs to the uridine kinase family. (211 aa)
SHK36795.1UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase. (411 aa)
SHK36833.1DNA polymerase-3 subunit delta'. (379 aa)
SHK37009.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (301 aa)
accDacetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (298 aa)
SHK39863.1DNA polymerase III, alpha subunit. (1228 aa)
queEOrganic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (210 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (303 aa)
SHK46067.1Predicted ATPase. (406 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (695 aa)
SHK48770.1Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (641 aa)
SHK48804.1Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase. (723 aa)
SHK50778.1Nicotinamide-nucleotide adenylyltransferase, NadR type. (353 aa)
SHK51729.1RNA polymerase sigma-70 factor, ECF subfamily. (179 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (434 aa)
SHK57209.1DNA polymerase (family 10). (584 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (716 aa)
SHK58011.16-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. (135 aa)
comB2-phosphosulfolactate phosphatase; Belongs to the ComB family. (240 aa)
queA-2S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (412 aa)
priAReplication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (849 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)
SHK67025.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (697 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (248 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa)
guaAGMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. (510 aa)
SHK77191.1dCTP deaminase. (178 aa)
SHK77310.1DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (374 aa)
SHK79915.1Competence/damage-inducible protein cinA; Belongs to the CinA family. (422 aa)
SHK85916.1Nicotinamide riboside kinase. (183 aa)
SHK88437.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (189 aa)
SHK88730.1Parallel beta-helix repeat (two copies). (764 aa)
SHK89258.1Dihydroorotate dehydrogenase. (250 aa)
SHK94144.1Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. (317 aa)
SHK95028.1ApaG protein. (128 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (583 aa)
SHK98426.16-pyruvoyltetrahydropterin/6- carboxytetrahydropterin synthase. (138 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa)
SHL01243.1RNA polymerase sigma-70 factor, ECF subfamily. (183 aa)
SHL02477.1AAA domain-containing protein, putative AbiEii toxin, Type IV TA system. (375 aa)
SHL02515.1Hypothetical protein. (245 aa)
SHL04095.1Adenylate cyclase, class 3. (315 aa)
SHL09346.1Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (454 aa)
SHL10344.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (248 aa)
SHL10802.1ElaA protein. (149 aa)
SHL12784.1Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (591 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (154 aa)
SHL18533.1Phosphomevalonate kinase. (182 aa)
SHL19030.1RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily. (189 aa)
SHL19335.1Hypothetical protein. (263 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
tdkThymidine kinase. (182 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. (511 aa)
SHL23162.1Uracil phosphoribosyltransferase. (230 aa)
pyrDDihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (344 aa)
SHL25183.1Predicted N-acyltransferase, GNAT family. (149 aa)
SHL27028.1Hypothetical protein. (1025 aa)
SHL27549.1RNA polymerase sigma-70 factor, ECF subfamily. (186 aa)
SHL33429.1Initiator Replication protein. (313 aa)
SHL34085.1Predicted ATP-binding protein involved in virulence. (451 aa)
dacATIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (281 aa)
SHL47097.1Nicotinamide-nucleotide amidase; Belongs to the CinA family. (175 aa)
SHL47387.1Deoxyadenosine/deoxycytidine kinase. (207 aa)
SHL49272.1rfaE bifunctional protein, domain I. (338 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (186 aa)
carACarbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (359 aa)
dinBDNA polymerase-4; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (359 aa)
SHL53632.1UDPglucose 6-dehydrogenase. (445 aa)
fclGDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (302 aa)
SHL54292.1WbqC-like protein family protein. (235 aa)
SHL54586.1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (207 aa)
SHL54756.1RNA polymerase sigma-70 factor, ECF subfamily. (168 aa)
SHL55472.1RNA polymerase Rpb6. (117 aa)
SHL55513.1Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase. (183 aa)
SHL56875.1WbqC-like protein family protein. (211 aa)
SHL58460.1Cell surface protein SprA. (2484 aa)
SHL59037.1dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (180 aa)
SHL59638.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (495 aa)
SHL60012.1Phosphoribosylformylglycinamidine cyclo-ligase. (367 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (502 aa)
purNPhosphoribosylglycinamide formyltransferase-1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (215 aa)
SHL60204.1Phosphoribosylamine--glycine ligase. (408 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (466 aa)
SHL60338.1Phosphoribosylformylglycinamidine synthase. (347 aa)
purLPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (1009 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (204 aa)
SHL60478.1Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). Belongs to the OMP decarboxylase family. Type 2 subfamily. (253 aa)
SHL60522.1Dihydroorotate dehydrogenase (NAD+) catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (285 aa)
SHL63108.1RNA polymerase sigma-70 factor, ECF subfamily. (216 aa)
SHL64552.1Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. (295 aa)
SHL66184.1Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (793 aa)
SHL66274.1Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (320 aa)
nadENAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (644 aa)
SHL70207.1RNA polymerase sigma-70 factor, ECF subfamily. (205 aa)
tgttRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (376 aa)
SHL70614.1ATP synthase F1 subcomplex epsilon subunit. (79 aa)
atpDATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (501 aa)
SHL70707.1Ribose-phosphate pyrophosphokinase. (309 aa)
SHL70745.1Hypothetical protein. (213 aa)
SHL73004.1RNA polymerase primary sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (287 aa)
SHL73776.1DNA polymerase III, delta subunit. (358 aa)
SHL78731.1RNA polymerase sigma-70 factor, ECF subfamily. (182 aa)
dnaXDNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (731 aa)
SHL85157.1Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
SHL90914.1Hypothetical protein. (98 aa)
SHL91603.1Toprim-like. (867 aa)
SHL93834.1RNA polymerase sigma-70 factor, ECF subfamily. (211 aa)
SHL94712.1Predicted N-acyltransferase, GNAT family. (144 aa)
SHL94888.1RNA polymerase sigma-70 factor, ECF subfamily. (171 aa)
SHL96173.1Initiator Replication protein. (309 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
SHM02538.1RNA polymerase sigma-70 factor, ECF subfamily. (196 aa)
SHM05005.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (882 aa)
SHM08129.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (284 aa)
SHM10069.1Toprim-like. (758 aa)
SHM12368.1Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (188 aa)
SHM14216.1DNA polymerase-3 subunit epsilon. (504 aa)
SHM15660.1RNA polymerase sigma-70 factor, ECF subfamily. (193 aa)
cmkCytidylate kinase. (240 aa)
SHM28678.1Initiator Replication protein. (375 aa)
SHM29968.1Initiator Replication protein. (324 aa)
SHM31928.1Initiator Replication protein. (315 aa)
Your Current Organism:
Hymenobacter psychrotolerans
NCBI taxonomy Id: 1121959
Other names: H. psychrotolerans DSM 18569, Hymenobacter psychrotolerans DSM 18569, Hymenobacter psychrotolerans Tibet-IIU11, Hymenobacter sp. Tibet-IIU11
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