STRINGSTRING
SHJ98918.1 SHJ98918.1 SHK00337.1 SHK00337.1 SHK01383.1 SHK01383.1 SHK02020.1 SHK02020.1 SHK06690.1 SHK06690.1 SHK09314.1 SHK09314.1 SHK09567.1 SHK09567.1 truA truA SHK18603.1 SHK18603.1 SHK19486.1 SHK19486.1 SHK26430.1 SHK26430.1 gmk gmk SHK31449.1 SHK31449.1 guaB guaB SHK35116.1 SHK35116.1 SHK36678.1 SHK36678.1 SHK39475.1 SHK39475.1 surE surE SHK50480.1 SHK50480.1 SHK52195.1 SHK52195.1 SHK52271.1 SHK52271.1 SHK59511.1 SHK59511.1 SHK59916.1 SHK59916.1 SHK59964.1 SHK59964.1 SHK61370.1 SHK61370.1 SHK70206.1 SHK70206.1 SHK70341.1 SHK70341.1 SHK71495.1 SHK71495.1 SHK72615.1 SHK72615.1 guaA guaA SHK76736.1 SHK76736.1 SHK78034.1 SHK78034.1 SHK80565.1 SHK80565.1 SHK81589.1 SHK81589.1 SHK81806.1 SHK81806.1 SHK86599.1 SHK86599.1 SHK93375.1 SHK93375.1 SHK95386.1 SHK95386.1 SHK97850.1 SHK97850.1 SHK98645.1 SHK98645.1 purA purA SHL03885.1 SHL03885.1 SHL04095.1 SHL04095.1 SHL05912.1 SHL05912.1 SHL09346.1 SHL09346.1 SHL09709.1 SHL09709.1 ychF ychF SHL14116.1 SHL14116.1 SHL17115.1 SHL17115.1 SHL17150.1 SHL17150.1 SHL17184.1 SHL17184.1 SHL18504.1 SHL18504.1 ndk ndk purH purH SHL27984.1 SHL27984.1 SHL35666.1 SHL35666.1 SHL43158.1 SHL43158.1 SHL47387.1 SHL47387.1 SHL47512.1 SHL47512.1 purE purE SHL51090.1 SHL51090.1 SHL54586.1 SHL54586.1 adk adk tilS tilS SHL59419.1 SHL59419.1 SHL59717.1 SHL59717.1 SHL60012.1 SHL60012.1 purF purF purN purN SHL60204.1 SHL60204.1 purC purC SHL60338.1 SHL60338.1 purL purL SHL66184.1 SHL66184.1 SHL66274.1 SHL66274.1 SHL68994.1 SHL68994.1 SHL69023.1 SHL69023.1 SHL69972.1 SHL69972.1 SHL70707.1 SHL70707.1 SHL83933.1 SHL83933.1 SHL83971.1 SHL83971.1 SHL85501.1 SHL85501.1 SHL88601.1 SHL88601.1 SHL91253.1 SHL91253.1 SHL93577.1 SHL93577.1 SHL94629.1 SHL94629.1 SHM04725.1 SHM04725.1 SHM04769.1 SHM04769.1 SHM04805.1 SHM04805.1 SHM09687.1 SHM09687.1 SHM12368.1 SHM12368.1 SHM13661.1 SHM13661.1 SHM13737.1 SHM13737.1 SHM14067.1 SHM14067.1 SHM18479.1 SHM18479.1 ade ade
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHJ98918.1LysM domain-containing protein. (95 aa)
SHK00337.1DNA-binding protein HU-beta; Belongs to the bacterial histone-like protein family. (101 aa)
SHK01383.1XTP/dITP diphosphohydrolase. (279 aa)
SHK02020.1CBS domain-containing protein. (228 aa)
SHK06690.1Magnesium transporter; Acts as a magnesium transporter. (461 aa)
SHK09314.1Type I restriction enzyme, R subunit. (814 aa)
SHK09567.1Hypothetical protein; Belongs to the LOG family. (287 aa)
truAtRNA pseudouridine38-40 synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (263 aa)
SHK18603.1Calcineurin-like phosphoesterase. (280 aa)
SHK19486.1Serine/threonine protein phosphatase 1. (232 aa)
SHK26430.1Predicted metal-dependent phosphohydrolase, HD superfamily. (210 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (194 aa)
SHK31449.1Exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase. (323 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa)
SHK35116.1FRG domain-containing protein. (279 aa)
SHK36678.1XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (197 aa)
SHK39475.1Hemolysin, contains CBS domains. (444 aa)
surE5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (291 aa)
SHK50480.1Nucleotidyltransferase. (93 aa)
SHK52195.1Predicted PurR-regulated permease PerM. (346 aa)
SHK52271.1Histidine triad (HIT) family protein. (293 aa)
SHK59511.1Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains. (326 aa)
SHK59916.15'-nucleotidase, C-terminal domain. (253 aa)
SHK59964.15'-nucleotidase; Belongs to the 5'-nucleotidase family. (308 aa)
SHK61370.18-oxo-dGTP pyrophosphatase MutT, NUDIX family. (192 aa)
SHK70206.1ADP-ribose pyrophosphatase. (171 aa)
SHK70341.1Calcineurin-like phosphoesterase. (908 aa)
SHK71495.1Hypothetical protein. (113 aa)
SHK72615.1S1/P1 Nuclease. (261 aa)
guaAGMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. (510 aa)
SHK76736.1dGTPase. (474 aa)
SHK78034.1Electron transfer flavoprotein beta subunit. (246 aa)
SHK80565.1N-acetyl sugar amidotransferase. (387 aa)
SHK81589.1AMP nucleosidase. (257 aa)
SHK81806.1DNA-binding protein, histone-like, putative. (144 aa)
SHK86599.18-oxo-dGTP pyrophosphatase MutT, NUDIX family. (185 aa)
SHK93375.1Hypothetical protein. (407 aa)
SHK95386.1Hypothetical protein. (361 aa)
SHK97850.1Por secretion system C-terminal sorting domain-containing protein. (423 aa)
SHK98645.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (735 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa)
SHL03885.1Por secretion system C-terminal sorting domain-containing protein. (373 aa)
SHL04095.1Adenylate cyclase, class 3. (315 aa)
SHL05912.1Phosphoglucomutase. (578 aa)
SHL09346.1Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (454 aa)
SHL09709.1Hypothetical protein; Belongs to the LOG family. (193 aa)
ychFHypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (365 aa)
SHL14116.1Serine/threonine protein phosphatase 1. (221 aa)
SHL17115.1Xanthine dehydrogenase YagT iron-sulfur-binding subunit. (214 aa)
SHL17150.1Xanthine dehydrogenase YagS FAD-binding subunit. (327 aa)
SHL17184.1Xanthine dehydrogenase YagR molybdenum-binding subunit. (746 aa)
SHL18504.1Putative hydrolase of the HAD superfamily. (231 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. (511 aa)
SHL27984.1Xanthine dehydrogenase YagR molybdenum-binding subunit. (82 aa)
SHL35666.1Bacteroides conjugative transposon TraN protein. (383 aa)
SHL43158.15-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (138 aa)
SHL47387.1Deoxyadenosine/deoxycytidine kinase. (207 aa)
SHL47512.1Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains. (310 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (186 aa)
SHL51090.1Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (272 aa)
SHL54586.1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (207 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (443 aa)
SHL59419.1Predicted metal-dependent phosphohydrolase, HD superfamily. (415 aa)
SHL59717.1Uncharacterized membrane-anchored protein YitT, contains DUF161 and DUF2179 domains. (324 aa)
SHL60012.1Phosphoribosylformylglycinamidine cyclo-ligase. (367 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (502 aa)
purNPhosphoribosylglycinamide formyltransferase-1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (215 aa)
SHL60204.1Phosphoribosylamine--glycine ligase. (408 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (466 aa)
SHL60338.1Phosphoribosylformylglycinamidine synthase. (347 aa)
purLPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (1009 aa)
SHL66184.1Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (793 aa)
SHL66274.1Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (320 aa)
SHL68994.1Xanthine dehydrogenase small subunit. (498 aa)
SHL69023.1Xanthine dehydrogenase large subunit. (774 aa)
SHL69972.1Pyruvate kinase; Belongs to the pyruvate kinase family. (479 aa)
SHL70707.1Ribose-phosphate pyrophosphokinase. (309 aa)
SHL83933.1Exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase. (331 aa)
SHL83971.1Por secretion system C-terminal sorting domain-containing protein. (330 aa)
SHL85501.1tRNA(Arg) A34 adenosine deaminase TadA. (158 aa)
SHL88601.1Hypothetical protein. (287 aa)
SHL91253.1Protein of unknown function. (300 aa)
SHL93577.1Phosphomannomutase. (482 aa)
SHL94629.1Hypothetical protein. (256 aa)
SHM04725.1Xanthine dehydrogenase YagR molybdenum-binding subunit. (743 aa)
SHM04769.1Xanthine dehydrogenase YagS FAD-binding subunit. (340 aa)
SHM04805.1Xanthine dehydrogenase YagT iron-sulfur-binding subunit. (179 aa)
SHM09687.1Protein of unknown function. (307 aa)
SHM12368.1Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (188 aa)
SHM13661.1Adenylate cyclase, class 3. (348 aa)
SHM13737.1Uncharacterized protein. (197 aa)
SHM14067.1Predicted PurR-regulated permease PerM. (393 aa)
SHM18479.1Por secretion system C-terminal sorting domain-containing protein. (609 aa)
adeAdenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (551 aa)
Your Current Organism:
Hymenobacter psychrotolerans
NCBI taxonomy Id: 1121959
Other names: H. psychrotolerans DSM 18569, Hymenobacter psychrotolerans DSM 18569, Hymenobacter psychrotolerans Tibet-IIU11, Hymenobacter sp. Tibet-IIU11
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