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| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (135 aa) |
| | SHE33666.1 | Uncharacterised 5xTM membrane BCR, YitT family COG1284. (206 aa) |
| | SHE38748.1 | Inosine-uridine nucleoside N-ribohydrolase; Belongs to the IUNH family. (313 aa) |
| | SHE40841.1 | Electron transfer flavoprotein beta subunit. (250 aa) |
| | SHE46649.1 | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (433 aa) |
| | ppnP | Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (96 aa) |
| | SHE48756.1 | Hypoxanthine phosphoribosyltransferase. (183 aa) |
| | SHE49064.1 | DNA-binding protein HU-beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa) |
| | SHE49794.1 | Hypothetical protein. (129 aa) |
| | SHE49833.1 | Hypothetical protein. (209 aa) |
| | SHE57990.1 | Magnesium and cobalt transporter. (288 aa) |
| | SHE60588.1 | dGTPase; Belongs to the dGTPase family. Type 2 subfamily. (448 aa) |
| | purH | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. (525 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (428 aa) |
| | SHE61668.1 | 7TMR-DISM extracellular 2. (765 aa) |
| | SHE61739.1 | Histidine triad (HIT) family protein. (113 aa) |
| | SHE61977.1 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (754 aa) |
| | SHE62028.1 | Ribonucleoside-diphosphate reductase beta chain. (377 aa) |
| | SHE63018.1 | Electron transfer flavoprotein beta subunit. (249 aa) |
| | SHE72493.1 | Electron transfer flavoprotein beta subunit. (249 aa) |
| | SHE73279.1 | Electron transfer flavoprotein beta subunit. (262 aa) |
| | SHE82159.1 | 2-polyprenyl-6-methoxyphenol hydroxylase. (372 aa) |
| | SHE85680.1 | Uncharacterized conserved protein. (135 aa) |
| | SHE86363.1 | Asp/Glu/hydantoin racemase. (224 aa) |
| | SHE88259.1 | Type I restriction enzyme, R subunit. (881 aa) |
| | SHE90068.1 | HAD superfamily, subfamily IIIB (Acid phosphatase). (150 aa) |
| | SHF01041.1 | Adenylate kinase. (177 aa) |
| | SHF01427.1 | Gamma-glutamyltranspeptidase / glutathione hydrolase. (545 aa) |
| | SHF01511.1 | (S)-ureidoglycine-glyoxylate aminotransferase. (406 aa) |
| | SHF01552.1 | Allantoate deiminase. (408 aa) |
| | SHF02049.1 | Putative urate catabolism protein. (308 aa) |
| | SHF02098.1 | Allantoin racemase. (243 aa) |
| | SHF04312.1 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (188 aa) |
| | SHF18065.1 | Putative hydrolase of the HAD superfamily. (226 aa) |
| | SHF18108.1 | Inosine/xanthosine triphosphatase; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. (186 aa) |
| | SHF18465.1 | CBS domain-containing protein. (197 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (180 aa) |
| | ttcA | tRNA s(2)C-32 sulfurtransferase; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (279 aa) |
| | SHF18950.1 | Transcriptional regulator, BolA protein family; Belongs to the BolA/IbaG family. (104 aa) |
| | cysN | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (537 aa) |
| | cysD | Sulfate adenylyltransferase subunit 2. (301 aa) |
| | SHF21530.1 | Phosphoglucomutase. (547 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (238 aa) |
| | SHF24367.1 | Putative permease. (353 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (501 aa) |
| | truA | tRNA pseudouridine38-40 synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (274 aa) |
| | SHF27346.1 | Uncharacterized conserved protein. (133 aa) |
| | SHF27928.1 | Uncharacterized conserved protein. (136 aa) |
| | SHF37304.1 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (705 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | rph | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (239 aa) |
| | SHF38560.1 | 5'-nucleotidase / UDP-sugar diphosphatase; Belongs to the 5'-nucleotidase family. (535 aa) |
| | SHF39196.1 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (207 aa) |
| | purK | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. (355 aa) |
| | purE | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa) |
| | SHF43872.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (482 aa) |
| | SHF45834.1 | Uncharacterized conserved protein YbbK, DUF523 family. (171 aa) |
| | SHF46756.1 | Uncharacterized membrane protein. (79 aa) |
| | SHF47259.1 | Ribose-phosphate pyrophosphokinase. (403 aa) |
| | SHF47304.1 | Nudix-type nucleoside diphosphatase, YffH/AdpP family. (193 aa) |
| | SHF48855.1 | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (749 aa) |
| | SHF48890.1 | ATP diphosphatase. (267 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa) |
| | tilS | tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (439 aa) |
| | surE | 5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (248 aa) |
| | SHF50681.1 | Uncharacterized membrane protein affecting hemolysin expression. (480 aa) |
| | SHF58025.1 | CBS domain-containing protein. (185 aa) |
| | SHF60835.1 | Magnesium transporter; Acts as a magnesium transporter. (450 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase-1; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (217 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (352 aa) |
| | SHF74443.1 | Hypothetical protein. (457 aa) |
| | SHF75746.1 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'-or 3'-nucleotidase, 5'-nucleotidase family. (501 aa) |
| | SHF79594.1 | Hypothetical protein. (171 aa) |
| | SHF83043.1 | Uncharacterized conserved protein. (146 aa) |
| | ureA | Urease subunit gamma; Belongs to the urease gamma subunit family. (100 aa) |
| | ureB | Urease subunit beta; Belongs to the urease beta subunit family. (105 aa) |
| | ureC | Urease subunit alpha. (568 aa) |
| | apaH | Bis(5'nucleosyl)-tetraphosphatase, ApaH; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. (275 aa) |
| | SHF87905.1 | Magnesium transporter. (443 aa) |
| | SHF93268.1 | Ureidoglycolate lyase. (282 aa) |
| | SHF97094.1 | Electron transfer flavoprotein beta subunit. (258 aa) |
| | SHF97485.1 | FAD-dependent urate hydroxylase. (392 aa) |
| | SHF97518.1 | 5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (123 aa) |
| | SHF97557.1 | OHCU decarboxylase. (173 aa) |
| | SHF97941.1 | Xanthine dehydrogenase small subunit. (502 aa) |
| | SHF97980.1 | Xanthine dehydrogenase, molybdenum binding subunit apoprotein. (776 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa) |
| | ihfA | Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (98 aa) |
| | gpt | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (165 aa) |
| | nrdR | Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (170 aa) |
| | SHG12784.1 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase; Belongs to the 5'-nucleotidase family. (644 aa) |
| | SHG14588.1 | Hypothetical protein; Belongs to the LOG family. (186 aa) |
| | SHG14675.1 | Endonuclease YncB, thermonuclease family. (248 aa) |
| | SHG19629.1 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (335 aa) |
| | SHG24116.1 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (457 aa) |
| | SHG25387.1 | Hemolysin, contains CBS domains. (427 aa) |
| | SHG29928.1 | GMP synthase-Glutamine amidotransferase. (236 aa) |
| | SHG30985.1 | ADP-ribose pyrophosphatase. (206 aa) |
| | SHG35245.1 | Inosine kinase. (432 aa) |
| | ihfB | Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (102 aa) |
| | SHG41818.1 | Uncharacterised 5xTM membrane BCR, YitT family COG1284. (200 aa) |
| | SHG64861.1 | Predicted PurR-regulated permease PerM. (345 aa) |
| | SHG66674.1 | Diadenosine tetraphosphate (Ap4A) hydrolase. (147 aa) |
| | guaA | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. (525 aa) |
| | guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | ychF | Hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa) |
| | SHG78416.1 | Carbamate kinase; Belongs to the carbamate kinase family. (309 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1299 aa) |
| | SHG85656.1 | Exopolyphosphatase / guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase; Belongs to the GppA/Ppx family. (505 aa) |
| | SHG85857.1 | Acetoin utilization protein AcuB. (133 aa) |
| | cpdA | 3',5'-cyclic AMP phosphodiesterase CpdA; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (274 aa) |
