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AQZ49400.1 AQZ49400.1 yfkN_1 yfkN_1 adeC_1 adeC_1 guaB guaB guaA_1 guaA_1 AQZ51326.1 AQZ51326.1 hpt hpt gmk gmk rihB rihB pcm_2 pcm_2 surE surE yfkN_2 yfkN_2 amn amn rihA rihA AQZ53234.1 AQZ53234.1 gpt gpt apt apt guaA_2 guaA_2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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AQZ49400.1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (320 aa)
yfkN_1Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family. (539 aa)
adeC_1Adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (600 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa)
guaA_1GMP synthase. (232 aa)
AQZ51326.1Glutamine amidotransferase. (240 aa)
hptHypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (212 aa)
rihBPyrimidine-specific ribonucleoside hydrolase RihB. (316 aa)
pcm_2Protein-L-isoaspartate O-methyltransferase. (217 aa)
surE5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (252 aa)
yfkN_2Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family. (662 aa)
amnAMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (497 aa)
rihAPyrimidine-specific ribonucleoside hydrolase RihA. (313 aa)
AQZ53234.1Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (214 aa)
gptXanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (166 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (179 aa)
guaA_2GMP synthase; Catalyzes the synthesis of GMP from XMP. (521 aa)
Your Current Organism:
Martelella mediterranea
NCBI taxonomy Id: 1122214
Other names: M. mediterranea DSM 17316, Martelella mediterranea DSM 17316
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