node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AQZ49400.1 | apt | Mame_00015 | Mame_04054 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.420 |
AQZ49400.1 | guaA_2 | Mame_00015 | Mame_04336 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.580 |
AQZ49400.1 | guaB | Mame_00015 | Mame_01101 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.432 |
AQZ49400.1 | rihA | Mame_00015 | Mame_03895 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Pyrimidine-specific ribonucleoside hydrolase RihA. | 0.915 |
AQZ49400.1 | rihB | Mame_00015 | Mame_02800 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Pyrimidine-specific ribonucleoside hydrolase RihB. | 0.926 |
AQZ49400.1 | surE | Mame_00015 | Mame_03280 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.912 |
AQZ49400.1 | yfkN_1 | Mame_00015 | Mame_00859 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family. | 0.929 |
AQZ49400.1 | yfkN_2 | Mame_00015 | Mame_03356 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family. | 0.916 |
AQZ51326.1 | AQZ53234.1 | Mame_01986 | Mame_03933 | Glutamine amidotransferase. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.907 |
AQZ51326.1 | apt | Mame_01986 | Mame_04054 | Glutamine amidotransferase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.922 |
AQZ51326.1 | gmk | Mame_01986 | Mame_02676 | Glutamine amidotransferase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.916 |
AQZ51326.1 | gpt | Mame_01986 | Mame_03941 | Glutamine amidotransferase. | Xanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.922 |
AQZ51326.1 | guaA_1 | Mame_01986 | Mame_01637 | Glutamine amidotransferase. | GMP synthase. | 0.923 |
AQZ51326.1 | guaA_2 | Mame_01986 | Mame_04336 | Glutamine amidotransferase. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.911 |
AQZ51326.1 | guaB | Mame_01986 | Mame_01101 | Glutamine amidotransferase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.980 |
AQZ51326.1 | hpt | Mame_01986 | Mame_02210 | Glutamine amidotransferase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.916 |
AQZ51326.1 | surE | Mame_01986 | Mame_03280 | Glutamine amidotransferase. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.925 |
AQZ51326.1 | yfkN_1 | Mame_01986 | Mame_00859 | Glutamine amidotransferase. | Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family. | 0.904 |
AQZ53234.1 | AQZ51326.1 | Mame_03933 | Mame_01986 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamine amidotransferase. | 0.907 |
AQZ53234.1 | apt | Mame_03933 | Mame_04054 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.575 |