STRINGSTRING
rpsT rpsT ywrD_2 ywrD_2 smpB smpB lepB lepB AQZ52342.1 AQZ52342.1 valS valS rpsI rpsI rplM rplM yigZ yigZ metG_1 metG_1 mhqO_1 mhqO_1 ywrD_1 ywrD_1 gatA_2 gatA_2 bioK_2 bioK_2 pdhC pdhC bfmBAB bfmBAB AQZ52057.1 AQZ52057.1 dcmA dcmA argS argS rpsF rpsF rpsR rpsR rplI rplI cysS cysS proS proS ackA ackA AQZ51861.1 AQZ51861.1 blh_2 blh_2 alaS_1 alaS_1 prfB prfB accC_2 accC_2 gatB gatB garB garB AQZ51726.1 AQZ51726.1 AQZ51717.1 AQZ51717.1 gatA_1 gatA_1 gatC gatC tuf_1 tuf_1 AQZ51628.1 AQZ51628.1 sspA sspA rpmB rpmB AQZ51550.1 AQZ51550.1 infA infA AQZ51517.1 AQZ51517.1 glyS glyS glyQ glyQ sucB sucB AQZ51428.1 AQZ51428.1 mcl2 mcl2 rpsO rpsO ureE ureE ureC ureC ureB ureB ureA2 ureA2 AQZ51384.1 AQZ51384.1 accA accA lepA lepA AQZ51351.1 AQZ51351.1 yfiY_2 yfiY_2 yfiY_1 yfiY_1 bioK_1 bioK_1 nanE_2 nanE_2 yjmC_1 yjmC_1 AQZ51145.1 AQZ51145.1 gstB_1 gstB_1 nanE_1 nanE_1 rplU rplU rpmA rpmA AQZ51050.1 AQZ51050.1 selA selA AQZ50966.1 AQZ50966.1 pdhB pdhB uao uao gshB gshB typA typA yghU yghU blh_1 blh_1 rpsA rpsA prfA prfA ureE1 ureE1 ureC1 ureC1 ureB1 ureB1 ureA ureA hutI hutI hutH_1 hutH_1 hutU hutU rpsU rpsU AQZ50612.1 AQZ50612.1 hisS_2 hisS_2 AQZ50511.1 AQZ50511.1 allA allA alc alc pucL pucL prfC prfC hemA hemA gltX_1 gltX_1 tesB tesB aacA4 aacA4 uup uup rpmF rpmF yfcF yfcF arcA_2 arcA_2 infC infC rpmI rpmI rplT rplT pheS pheS pheT pheT yaeJ yaeJ coaBC coaBC leuS leuS acsA_2 acsA_2 fgs fgs accD accD bclA bclA AQZ49914.1 AQZ49914.1 acsA_1 acsA_1 yibF_1 yibF_1 linE linE tpa tpa AQZ49459.1 AQZ49459.1 efp efp epmA epmA ybaK_1 ybaK_1 tsf tsf rpsB rpsB mhqO_2 mhqO_2 alaS_2 alaS_2 yibF_2 yibF_2 ligE ligE yheS yheS serS serS gstB_2 gstB_2 nqo2 nqo2 rpsD rpsD folK folK folB folB folP folP rpmG rpmG tyrS tyrS AQZ52772.1 AQZ52772.1 thrS thrS rpmE rpmE yfcG_1 yfcG_1 ggt ggt aspS aspS fmt fmt def def gstB_3 gstB_3 ileS ileS yfcG_2 yfcG_2 AQZ53186.1 AQZ53186.1 gshA gshA trpS trpS rplQ rplQ rpsK rpsK rpsM rpsM rplO rplO rpmD rpmD rpsE rpsE rplR rplR rplF rplF rpsH rpsH rpsN rpsN rplE rplE rplX rplX rplN rplN rpsQ rpsQ rpmC rpmC rplP rplP rpsC rpsC rplV rplV rpsS rpsS rplB rplB rplW rplW rplD rplD rplC rplC rpsJ rpsJ tuf_2 tuf_2 fusA fusA rpsG rpsG rpsL rpsL AQZ53287.1 AQZ53287.1 rplL rplL rplJ rplJ rplA rplA rplK rplK metG_2 metG_2 rplY rplY pth pth yqjG yqjG infB infB AQZ53391.1 AQZ53391.1 cysNC cysNC rplS rplS rpsP rpsP AQZ53550.1 AQZ53550.1 lysS lysS gltX_2 gltX_2 rpmJ rpmJ frr frr
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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rpsT30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (88 aa)
ywrD_2Putative gamma-glutamyltransferase YwrD. (529 aa)
smpBSsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (159 aa)
lepBSignal peptidase I; Belongs to the peptidase S26 family. (259 aa)
AQZ52342.1Beta-lactamase TEM. (286 aa)
valSValine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (970 aa)
rpsI30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (159 aa)
rplM50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (154 aa)
yigZIMPACT family member YigZ. (196 aa)
metG_1Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (548 aa)
mhqO_1Putative ring-cleaving dioxygenase MhqO. (311 aa)
ywrD_1Putative gamma-glutamyltransferase YwrD. (528 aa)
gatA_2Glutamyl-tRNA(Gln) amidotransferase subunit A; Belongs to the amidase family. (385 aa)
bioK_2L-Lysine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa)
pdhCDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (468 aa)
bfmBAB2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (464 aa)
AQZ52057.1Putative acyl-CoA thioester hydrolase. (129 aa)
dcmADichloromethane dehalogenase. (220 aa)
argSArginine--tRNA ligase. (586 aa)
rpsF30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (145 aa)
rpsR30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (82 aa)
rplI50S ribosomal protein L9; Binds to the 23S rRNA. (208 aa)
cysSCysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (464 aa)
proSProline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. (442 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
AQZ51861.1Energy-dependent translational throttle protein EttA. (549 aa)
blh_2Beta-lactamase hydrolase-like protein. (112 aa)
alaS_1Alanine--tRNA ligase. (240 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (321 aa)
accC_2Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
gatBAspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (500 aa)
garBGlutathione amide reductase; Maintains high levels of reduced glutathione. (462 aa)
AQZ51726.1Glutathionine S-transferase. (225 aa)
AQZ51717.127 kDa antigen Cfp30B. (258 aa)
gatA_1Glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (493 aa)
gatCGlutamyl-tRNA(Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (95 aa)
tuf_1Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (391 aa)
AQZ51628.1Putative enzyme related to lactoylglutathione lyase. (119 aa)
sspAStringent starvation protein A. (224 aa)
rpmB50S ribosomal protein L28; RRP-L28; Belongs to the bacterial ribosomal protein bL28 family. (98 aa)
AQZ51550.1Putative protein involved in cation transport; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (183 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa)
AQZ51517.1Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (241 aa)
glySGlycine--tRNA ligase beta subunit. (704 aa)
glyQGlycine--tRNA ligase alpha subunit. (316 aa)
sucBDihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (409 aa)
AQZ51428.1AFG1-like ATPase. (384 aa)
mcl2(3S)-malyl-CoA thioesterase; Belongs to the HpcH/HpaI aldolase family. (297 aa)
rpsO30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (89 aa)
ureEUrease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (217 aa)
ureCUrease subunit alpha. (572 aa)
ureBUrease subunit beta; Belongs to the urease beta subunit family. (135 aa)
ureA2Urease subunit gamma 2; Belongs to the urease gamma subunit family. (100 aa)
AQZ51384.1Imidazolonepropionase. (482 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
lepAElongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (608 aa)
AQZ51351.1Putative acyl-CoA thioester hydrolase. (161 aa)
yfiY_2Putative siderophore-binding lipoprotein YfiY precursor. (301 aa)
yfiY_1Putative siderophore-binding lipoprotein YfiY precursor. (310 aa)
bioK_1L-Lysine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (451 aa)
nanE_2Putative N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (511 aa)
yjmC_1Putative oxidoreductase YjmC; Belongs to the LDH2/MDH2 oxidoreductase family. (352 aa)
AQZ51145.1Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (441 aa)
gstB_1Glutathione S-transferase GST-6.0; Belongs to the GST superfamily. (194 aa)
nanE_1Putative N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (223 aa)
rplU50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (104 aa)
rpmA50S ribosomal protein L27; RRP-L27; Belongs to the bacterial ribosomal protein bL27 family. (90 aa)
AQZ51050.1Putative lyase. (132 aa)
selAL-seryl-tRNA(Sec) selenium transferase. (410 aa)
AQZ50966.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (339 aa)
pdhBPyruvate dehydrogenase E1 component subunit beta. (729 aa)
uaoUric acid degradation bifunctional protein. (179 aa)
gshBGlutathione synthetase; Belongs to the prokaryotic GSH synthase family. (317 aa)
typATyrosine phosphorylated protein A. (607 aa)
yghUDisulfide-bond oxidoreductase YghU. (294 aa)
blh_1Beta-lactamase hydrolase-like protein. (297 aa)
rpsA30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (568 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa)
ureE1Urease accessory protein UreE 1; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (156 aa)
ureC1Urease subunit alpha 1. (570 aa)
ureB1Urease subunit beta 1; Belongs to the urease beta subunit family. (101 aa)
ureAUrease subunit gamma; Belongs to the urease gamma subunit family. (100 aa)
hutIImidazolonepropionase. (404 aa)
hutH_1Histidine ammonia-lyase. (511 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (558 aa)
rpsU30S ribosomal protein S21; RRP-S21; Belongs to the bacterial ribosomal protein bS21 family. (74 aa)
AQZ50612.1Dihydrolipoamide dehydrogenase. (392 aa)
hisS_2Histidine--tRNA ligase. (506 aa)
AQZ50511.1Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa)
allAUreidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source. (165 aa)
alcAllantoicase; Belongs to the allantoicase family. (343 aa)
pucLUric acid degradation bifunctional protein PucL. (164 aa)
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (527 aa)
hemA5-aminolevulinate synthase. (404 aa)
gltX_1Glutamate--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (292 aa)
tesBAcyl-CoA thioesterase 2. (298 aa)
aacA4Aminoglycoside N(6')-acetyltransferase type 1. (167 aa)
uupABC transporter ATP-binding protein uup. (605 aa)
rpmF50S ribosomal protein L32; RRP-L32; Belongs to the bacterial ribosomal protein bL32 family. (61 aa)
yfcFGlutathione S-transferase YfcF. (215 aa)
arcA_2Arginase; Belongs to the arginase family. (307 aa)
infCTranslation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (151 aa)
rpmI50S ribosomal protein L35; RRP-L35; Belongs to the bacterial ribosomal protein bL35 family. (66 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (134 aa)
pheSPhenylalanine--tRNA ligase alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (360 aa)
pheTPhenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (813 aa)
yaeJPeptidyl-tRNA hydrolase YaeJ. (145 aa)
coaBCDNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (399 aa)
leuSLeucine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (876 aa)
acsA_2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)
fgsFolylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (447 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (316 aa)
bclABenzoate--CoA ligase. (540 aa)
AQZ49914.1Citrate lyase subunit beta-like protein; Belongs to the HpcH/HpaI aldolase family. (265 aa)
acsA_1Acetyl-coenzyme A synthetase. (519 aa)
yibF_1Putative GST-like protein YibF. (220 aa)
linEChlorohydroquinone/hydroquinone 1,2-dioxygenase. (319 aa)
tpaTaurine--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa)
AQZ49459.1Putative enzyme related to lactoylglutathione lyase. (120 aa)
efpElongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (189 aa)
epmAElongation factor P--(R)-beta-lysine ligase. (356 aa)
ybaK_1Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (157 aa)
tsfElongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (308 aa)
rpsB30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (269 aa)
mhqO_2Putative ring-cleaving dioxygenase MhqO. (310 aa)
alaS_2Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (884 aa)
yibF_2Putative GST-like protein YibF. (200 aa)
ligEBeta-aryl ether cleaving enzyme. (222 aa)
yheSPutative ABC transporter ATP-binding protein YheS. (626 aa)
serSSerine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (427 aa)
gstB_2Glutathione S-transferase GST-6.0; Belongs to the GST superfamily. (206 aa)
nqo2NADH-quinone oxidoreductase chain 2. (322 aa)
rpsD30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (205 aa)
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (170 aa)
folBDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (122 aa)
folPDihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (290 aa)
rpmG50S ribosomal protein L33; RRP-L33; Belongs to the bacterial ribosomal protein bL33 family. (55 aa)
tyrSTyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (417 aa)
AQZ52772.1Citrate lyase beta subunit. (224 aa)
thrSThreonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (655 aa)
rpmE50S ribosomal protein L31; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. (73 aa)
yfcG_1Disulfide-bond oxidoreductase YfcG; Belongs to the GST superfamily. (232 aa)
ggtGamma-glutamyltranspeptidase precursor. (600 aa)
aspSAspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (595 aa)
fmtMethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (312 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (177 aa)
gstB_3Glutathione S-transferase GST-6.0; Belongs to the GST superfamily. (195 aa)
ileSIsoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). (1024 aa)
yfcG_2Disulfide-bond oxidoreductase YfcG; Belongs to the GST superfamily. (238 aa)
AQZ53186.1Putative enzyme related to lactoylglutathione lyase. (116 aa)
gshAGlutamate--cysteine ligase GshA; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (457 aa)
trpSTryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (353 aa)
rplQ50S ribosomal protein L17. (142 aa)
rpsK30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
rpsM30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (122 aa)
rplO50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (158 aa)
rpmD50S ribosomal protein L30. (66 aa)
rpsE30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (189 aa)
rplR50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (120 aa)
rplF50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa)
rpsH30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rpsN30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
rplE50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (185 aa)
rplXrplX; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (103 aa)
rplNrplN; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpsQ30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (81 aa)
rpmCrpmC; RRP-L29; Belongs to the universal ribosomal protein uL29 family. (66 aa)
rplP50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (137 aa)
rpsCrpsC; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (237 aa)
rplVrplV; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (127 aa)
rpsSrpsS; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
rplBrplB; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (278 aa)
rplW50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (97 aa)
rplD50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (206 aa)
rplC50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (231 aa)
rpsJrpsJ; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
tuf_2Elongation factor Tu. (391 aa)
fusAElongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (699 aa)
rpsG30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsLrpsL; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (123 aa)
AQZ53287.1Putative ABC transporter ATP-binding protein. (530 aa)
rplL50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (125 aa)
rplJ50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (172 aa)
rplA50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (234 aa)
rplK50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa)
metG_2Methionine--tRNA ligase. (113 aa)
rplYGeneral stress protein CTC; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (218 aa)
pthPeptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (238 aa)
yqjGGlutathionyl-hydroquinone reductase YqjG. (323 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (915 aa)
AQZ53391.1Maleylacetoacetate isomerase. (230 aa)
cysNCBifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (630 aa)
rplS50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (155 aa)
rpsP30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (127 aa)
AQZ53550.1Hypothetical protein. (116 aa)
lysSLysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family. (495 aa)
gltX_2Glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (488 aa)
rpmJ50S ribosomal protein L36; RRP-L36; Belongs to the bacterial ribosomal protein bL36 family. (41 aa)
frrRibosome-releasing factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (186 aa)
Your Current Organism:
Martelella mediterranea
NCBI taxonomy Id: 1122214
Other names: M. mediterranea DSM 17316, Martelella mediterranea DSM 17316
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