(18 nodes) Thiamin diphosphate-binding fold network (Martelella mediterranea)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	tktA	Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (660 aa)
	poxB	Pyruvate dehydrogenase; Belongs to the TPP enzyme family. (570 aa)
	dxs_3	1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (639 aa)
	xsc_2	Sulfoacetaldehyde acetyltransferase; Belongs to the TPP enzyme family. (593 aa)
	bfmBAB	2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (464 aa)
	acoA	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (340 aa)
	ilvI	Acetolactate synthase isozyme 3 large subunit. (590 aa)
	xpkA	Xylulose-5-phosphate phosphoketolase. (799 aa)
	xsc_1	Sulfoacetaldehyde acetyltransferase; Belongs to the TPP enzyme family. (591 aa)
	iolD	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Belongs to the TPP enzyme family. (607 aa)
	sucA	2-oxoglutarate dehydrogenase E1 component. (994 aa)
	ilvX	Putative acetolactate synthase large subunit IlvX. (519 aa)
	dxs_2	1-deoxy-D-xylulose-5-phosphate synthase. (333 aa)
	tkt	Transketolase. (311 aa)
	pdhB	Pyruvate dehydrogenase E1 component subunit beta. (729 aa)
	tktB	Transketolase 2. (273 aa)
	dxs_1	1-deoxy-D-xylulose-5-phosphate synthase. (319 aa)
	AQZ49663.1	2-oxoacid ferredoxin oxidoreductase. (717 aa)

Your Current Organism:

Martelella mediterranea

NCBI taxonomy Id: 1122214
Other names: M. mediterranea DSM 17316, Martelella mediterranea DSM 17316

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
acoA	bfmBAB	Mame_02758	Mame_02759	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.999
acoA	dxs_1	Mame_02758	Mame_00457	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	1-deoxy-D-xylulose-5-phosphate synthase.	0.807
acoA	dxs_2	Mame_02758	Mame_01571	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	1-deoxy-D-xylulose-5-phosphate synthase.	0.807
acoA	ilvI	Mame_02758	Mame_02726	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Acetolactate synthase isozyme 3 large subunit.	0.820
acoA	ilvX	Mame_02758	Mame_01704	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Putative acetolactate synthase large subunit IlvX.	0.820
acoA	pdhB	Mame_02758	Mame_01542	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Pyruvate dehydrogenase E1 component subunit beta.	0.973
acoA	poxB	Mame_02758	Mame_04348	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Pyruvate dehydrogenase; Belongs to the TPP enzyme family.	0.910
acoA	sucA	Mame_02758	Mame_02094	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	2-oxoglutarate dehydrogenase E1 component.	0.680
acoA	tkt	Mame_02758	Mame_01570	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Transketolase.	0.807
acoA	tktA	Mame_02758	Mame_03755	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Transketolase 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.	0.840
acoA	tktB	Mame_02758	Mame_00458	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Transketolase 2.	0.807
acoA	xpkA	Mame_02758	Mame_02542	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Xylulose-5-phosphate phosphoketolase.	0.800
bfmBAB	acoA	Mame_02759	Mame_02758	2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.999
bfmBAB	dxs_1	Mame_02759	Mame_00457	2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	1-deoxy-D-xylulose-5-phosphate synthase.	0.817
bfmBAB	dxs_2	Mame_02759	Mame_01571	2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	1-deoxy-D-xylulose-5-phosphate synthase.	0.807
bfmBAB	ilvI	Mame_02759	Mame_02726	2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Acetolactate synthase isozyme 3 large subunit.	0.824
bfmBAB	ilvX	Mame_02759	Mame_01704	2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Putative acetolactate synthase large subunit IlvX.	0.824
bfmBAB	pdhB	Mame_02759	Mame_01542	2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Pyruvate dehydrogenase E1 component subunit beta.	0.982
bfmBAB	poxB	Mame_02759	Mame_04348	2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	Pyruvate dehydrogenase; Belongs to the TPP enzyme family.	0.912
bfmBAB	sucA	Mame_02759	Mame_02094	2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	2-oxoglutarate dehydrogenase E1 component.	0.836