(23 nodes) Lysine degradation network (Martelella mediterranea)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gabD_1	Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; Belongs to the aldehyde dehydrogenase family. (494 aa)
	fadB_1	Putative enoyl-CoA hydratase. (352 aa)
	comC	(2R)-3-sulfolactate dehydrogenase (NADP(+)); Belongs to the LDH2/MDH2 oxidoreductase family. (346 aa)
	thlA	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (386 aa)
	fadA_1	Putative acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	echA8_3	Putative enoyl-CoA hydratase echA8. (264 aa)
	caiD_2	Carnitinyl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
	gabD_2	Succinate-semialdehyde dehydrogenase [NADP(+)] GabD. (492 aa)
	dat	D-alanine aminotransferase. (285 aa)
	ald_1	3-succinoylsemialdehyde-pyridine dehydrogenase. (478 aa)
	phbA_1	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	ald_2	3-succinoylsemialdehyde-pyridine dehydrogenase. (474 aa)
	ald_3	3-succinoylsemialdehyde-pyridine dehydrogenase. (475 aa)
	acdA_2	Acyl-CoA dehydrogenase. (400 aa)
	fadA_2	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
	mmgC_4	Acyl-CoA dehydrogenase. (400 aa)
	sucB	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (409 aa)
	lpd3	Dihydrolipoyl dehydrogenase 3. (468 aa)
	lpd_1	Dihydrolipoyl dehydrogenase. (481 aa)
	phbA_2	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	paaF_2	2,3-dehydroadipyl-CoA hydratase. (257 aa)
	AQZ53084.1	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
	kamA	L-lysine 2,3-aminomutase. (352 aa)

Your Current Organism:

Martelella mediterranea

NCBI taxonomy Id: 1122214
Other names: M. mediterranea DSM 17316, Martelella mediterranea DSM 17316

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQZ53084.1	caiD_2	Mame_03782	Mame_00527	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Carnitinyl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.572
AQZ53084.1	echA8_3	Mame_03782	Mame_00522	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Putative enoyl-CoA hydratase echA8.	0.585
AQZ53084.1	fadA_1	Mame_03782	Mame_00508	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Putative acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.618
AQZ53084.1	fadA_2	Mame_03782	Mame_01580	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.600
AQZ53084.1	fadB_1	Mame_03782	Mame_00180	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Putative enoyl-CoA hydratase.	0.572
AQZ53084.1	paaF_2	Mame_03782	Mame_03732	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	2,3-dehydroadipyl-CoA hydratase.	0.572
AQZ53084.1	phbA_1	Mame_03782	Mame_00888	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.600
AQZ53084.1	phbA_2	Mame_03782	Mame_03031	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.600
AQZ53084.1	sucB	Mame_03782	Mame_02095	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.821
AQZ53084.1	thlA	Mame_03782	Mame_00506	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.600
acdA_2	caiD_2	Mame_01541	Mame_00527	Acyl-CoA dehydrogenase.	Carnitinyl-CoA dehydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.938
acdA_2	echA8_3	Mame_01541	Mame_00522	Acyl-CoA dehydrogenase.	Putative enoyl-CoA hydratase echA8.	0.939
acdA_2	fadA_2	Mame_01541	Mame_01580	Acyl-CoA dehydrogenase.	3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.659
acdA_2	fadB_1	Mame_01541	Mame_00180	Acyl-CoA dehydrogenase.	Putative enoyl-CoA hydratase.	0.949
acdA_2	lpd3	Mame_01541	Mame_02098	Acyl-CoA dehydrogenase.	Dihydrolipoyl dehydrogenase 3.	0.907
acdA_2	lpd_1	Mame_01541	Mame_02763	Acyl-CoA dehydrogenase.	Dihydrolipoyl dehydrogenase.	0.907
acdA_2	mmgC_4	Mame_01541	Mame_01855	Acyl-CoA dehydrogenase.	Acyl-CoA dehydrogenase.	0.900
acdA_2	paaF_2	Mame_01541	Mame_03732	Acyl-CoA dehydrogenase.	2,3-dehydroadipyl-CoA hydratase.	0.938
acdA_2	sucB	Mame_01541	Mame_02095	Acyl-CoA dehydrogenase.	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.912
acdA_2	thlA	Mame_01541	Mame_00506	Acyl-CoA dehydrogenase.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.659