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mhpF mhpF acsA_1 acsA_1 thlA thlA fadA_1 fadA_1 tme tme cfiB cfiB accD accD acsA_2 acsA_2 pckA pckA ald_1 ald_1 ydiF ydiF phbA_1 phbA_1 ald_2 ald_2 glcB glcB lldD lldD dme dme ghrA_1 ghrA_1 ald_3 ald_3 mdlB mdlB fadA_2 fadA_2 AQZ51070.1 AQZ51070.1 accC_1 accC_1 accB_1 accB_1 ttdB ttdB ttdA ttdA accA accA mdh_2 mdh_2 lpd3 lpd3 gloB gloB eutD eutD fumC fumC accC_2 accC_2 accB_2 accB_2 AQZ51826.1 AQZ51826.1 ackA ackA leuA_1 leuA_1 acoA acoA bfmBAB bfmBAB pdhC pdhC lpd_1 lpd_1 phbA_2 phbA_2 gloA_1 gloA_1 acoD acoD ttuE ttuE blh_3 blh_3 sucD_2 sucD_2 ppdK ppdK AQZ53084.1 AQZ53084.1 leuA_2 leuA_2 poxB poxB ldhA ldhA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
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gene co-occurrence
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Your Input:
mhpFAcetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (314 aa)
acsA_1Acetyl-coenzyme A synthetase. (519 aa)
thlAAcetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (386 aa)
fadA_1Putative acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
tmeNADP-dependent malic enzyme. (772 aa)
cfiB2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1153 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (316 aa)
acsA_2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (652 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (535 aa)
ald_13-succinoylsemialdehyde-pyridine dehydrogenase. (478 aa)
ydiFAcetate CoA-transferase YdiF; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family. (524 aa)
phbA_1Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
ald_23-succinoylsemialdehyde-pyridine dehydrogenase. (474 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (722 aa)
lldDL-lactate dehydrogenase. (382 aa)
dmeNAD-dependent malic enzyme. (774 aa)
ghrA_1Glyoxylate/hydroxypyruvate reductase A. (319 aa)
ald_33-succinoylsemialdehyde-pyridine dehydrogenase. (475 aa)
mdlB(S)-mandelate dehydrogenase. (396 aa)
fadA_23-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
AQZ51070.1Hypothetical protein. (132 aa)
accC_1Biotin carboxylase. (456 aa)
accB_1Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (140 aa)
ttdBL(+)-tartrate dehydratase subunit beta. (206 aa)
ttdAL(+)-tartrate dehydratase subunit alpha. (289 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
mdh_2Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
lpd3Dihydrolipoyl dehydrogenase 3. (468 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (256 aa)
eutDEthanolamine utilization protein EutD. (334 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
accC_2Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
accB_2Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (158 aa)
AQZ51826.1Putative FAD-linked oxidoreductase. (467 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
leuA_12-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (539 aa)
acoAAcetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (340 aa)
bfmBAB2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (464 aa)
pdhCDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (468 aa)
lpd_1Dihydrolipoyl dehydrogenase. (481 aa)
phbA_2Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
gloA_1Lactoylglutathione lyase. (146 aa)
acoDAcetaldehyde dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (506 aa)
ttuEPyruvate kinase; Belongs to the pyruvate kinase family. (479 aa)
blh_3Beta-lactamase hydrolase-like protein. (227 aa)
sucD_2Succinyl-CoA ligase [ADP-forming] subunit alpha. (716 aa)
ppdKPyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (891 aa)
AQZ53084.1acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (385 aa)
leuA_22-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (566 aa)
poxBPyruvate dehydrogenase; Belongs to the TPP enzyme family. (570 aa)
ldhAD-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (330 aa)
Your Current Organism:
Martelella mediterranea
NCBI taxonomy Id: 1122214
Other names: M. mediterranea DSM 17316, Martelella mediterranea DSM 17316
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