STRINGSTRING
AJ81_01305 AJ81_01305 AJ81_00365 AJ81_00365 rpoC rpoC rpoB rpoB coaD coaD glmU glmU AJ81_00820 AJ81_00820 rpoA rpoA AJ81_01125 AJ81_01125 rpoZ rpoZ AJ81_01345 AJ81_01345 AJ81_01615 AJ81_01615 AJ81_01945 AJ81_01945 AJ81_01965 AJ81_01965 dnaX dnaX AJ81_02430 AJ81_02430 AJ81_02625 AJ81_02625 AJ81_03120 AJ81_03120 dnaG dnaG AJ81_03920 AJ81_03920 pnp pnp AJ81_04540 AJ81_04540 nadD nadD polC polC guaA guaA polA polA AJ81_05755 AJ81_05755 AJ81_06595 AJ81_06595 AJ81_06745 AJ81_06745 glgC glgC AJ81_07310 AJ81_07310 AJ81_07935 AJ81_07935 AJ81_08410 AJ81_08410 AJ81_08655 AJ81_08655 AJ81_08805 AJ81_08805 AJ81_08945 AJ81_08945 AJ81_09405 AJ81_09405 thiI thiI AJ81_09920 AJ81_09920 AJ81_10370 AJ81_10370
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJ81_01305Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
AJ81_00365DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (367 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1650 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1172 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa)
glmUN-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (448 aa)
AJ81_00820RNA polymerase subunit sigma-28; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (236 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (333 aa)
AJ81_01125Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (76 aa)
AJ81_01345Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
AJ81_01615Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (337 aa)
AJ81_01945Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
AJ81_01965DNA-directed DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (843 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (469 aa)
AJ81_02430Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (280 aa)
AJ81_02625Glucose-1-phosphate thymidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
AJ81_03120Phosphatidate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. (271 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (558 aa)
AJ81_03920Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (725 aa)
AJ81_04540Galactose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
nadDNicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (209 aa)
polCDNA polymerase III; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1370 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (504 aa)
polADNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (892 aa)
AJ81_05755CRISPR-associated protein Csh2; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
AJ81_06595tRNA nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (877 aa)
AJ81_06745Glucose-1-phosphate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (368 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (420 aa)
AJ81_07310Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (314 aa)
AJ81_07935Phage-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
AJ81_08410Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (371 aa)
AJ81_08655Galactose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
AJ81_08805Glycerol-3-phosphate cytidiltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
AJ81_08945Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (233 aa)
AJ81_09405Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (536 aa)
thiIThiamin biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (363 aa)
AJ81_09920DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
AJ81_10370DNA integrity scanning protein DisA; Non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DisA family. (357 aa)
Your Current Organism:
Pseudothermotoga hypogea
NCBI taxonomy Id: 1123384
Other names: P. hypogea DSM 11164 = NBRC 106472, Pseudothermotoga hypogea DSM 11164, Pseudothermotoga hypogea DSM 11164 = NBRC 106472, Pseudothermotoga hypogea NBRC 106472, Pseudothermotoga hypogea NBRC 106472 = DSM 11164, Thermotoga hypogea DSM 11164, Thermotoga hypogea DSM 11164 = NBRC 106472, Thermotoga hypogea NBRC 106472
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