STRINGSTRING
AJ81_01970 AJ81_01970 AJ81_01965 AJ81_01965 truB truB rbfA rbfA mutS2 mutS2 gyrB gyrB AJ81_01780 AJ81_01780 AJ81_01755 AJ81_01755 AJ81_01725 AJ81_01725 tdk tdk AJ81_01660 AJ81_01660 AJ81_01615 AJ81_01615 AJ81_01360 AJ81_01360 AJ81_01345 AJ81_01345 rpoZ rpoZ mutS mutS AJ81_01265 AJ81_01265 AJ81_01260 AJ81_01260 AJ81_01245 AJ81_01245 AJ81_01195 AJ81_01195 AJ81_01160 AJ81_01160 AJ81_01100 AJ81_01100 AJ81_01085 AJ81_01085 uvrC uvrC tmcAL tmcAL rpoA rpoA rho rho mfd mfd AJ81_00820 AJ81_00820 tgt tgt priA priA glyS glyS glyQ glyQ nusG nusG rpoB rpoB rpoC rpoC AJ81_00385 AJ81_00385 AJ81_00365 AJ81_00365 AJ81_00350 AJ81_00350 nfi nfi AJ81_00225 AJ81_00225 lysS lysS AJ81_00080 AJ81_00080 AJ81_00060 AJ81_00060 AJ81_00055 AJ81_00055 topA topA AJ81_00035 AJ81_00035 AJ81_00030 AJ81_00030 AJ81_02700 AJ81_02700 metG metG gyrA gyrA AJ81_02715 AJ81_02715 AJ81_08000 AJ81_08000 AJ81_08015 AJ81_08015 AJ81_08135 AJ81_08135 nth nth nusB nusB AJ81_08370 AJ81_08370 AJ81_08410 AJ81_08410 gltX-2 gltX-2 AJ81_08440 AJ81_08440 AJ81_08465 AJ81_08465 mrnC mrnC AJ81_08485 AJ81_08485 AJ81_08500 AJ81_08500 AJ81_08600 AJ81_08600 AJ81_08700 AJ81_08700 AJ81_08705 AJ81_08705 AJ81_08720 AJ81_08720 AJ81_08960 AJ81_08960 AJ81_08985 AJ81_08985 AJ81_08990 AJ81_08990 AJ81_08995 AJ81_08995 AJ81_09005 AJ81_09005 AJ81_09195 AJ81_09195 AJ81_09200 AJ81_09200 rsmH rsmH AJ81_09380 AJ81_09380 thiI thiI pheT pheT pheS pheS AJ81_09570 AJ81_09570 rnc rnc AJ81_09595 AJ81_09595 tilS tilS AJ81_09850 AJ81_09850 rlmH rlmH AJ81_09920 AJ81_09920 rimM rimM trmD trmD AJ81_10045 AJ81_10045 AJ81_10155 AJ81_10155 mutL mutL ligA ligA rnpA rnpA AJ81_10370 AJ81_10370 AJ81_10375 AJ81_10375 miaA miaA AJ81_10425 AJ81_10425 AJ81_10490 AJ81_10490 gltX gltX cysS cysS hisS hisS AJ81_10535 AJ81_10535 AJ81_10565 AJ81_10565 rnr rnr AJ81_10610 AJ81_10610 mnmA mnmA AJ81_10725 AJ81_10725 AJ81_10855 AJ81_10855 AJ81_04760 AJ81_04760 AJ81_05215 AJ81_05215 AJ81_05295 AJ81_05295 AJ81_05305 AJ81_05305 cas2 cas2 cas2-2 cas2-2 AJ81_05380 AJ81_05380 AJ81_05390 AJ81_05390 cas1 cas1 AJ81_05440 AJ81_05440 ruvC ruvC polC polC rsmG rsmG rsmI rsmI AJ81_05520 AJ81_05520 serS serS AJ81_05535 AJ81_05535 AJ81_05635 AJ81_05635 rtcB rtcB polA polA proS proS AJ81_05750 AJ81_05750 AJ81_05755 AJ81_05755 cas2-3 cas2-3 cas1-2 cas1-2 AJ81_05775 AJ81_05775 recG recG AJ81_06110 AJ81_06110 AJ81_06130 AJ81_06130 AJ81_06135 AJ81_06135 AJ81_06170 AJ81_06170 cas1-3 cas1-3 cas2-4 cas2-4 AJ81_06375 AJ81_06375 sbcD sbcD AJ81_06430 AJ81_06430 AJ81_06460 AJ81_06460 AJ81_06530 AJ81_06530 aspS aspS AJ81_06595 AJ81_06595 nusA nusA AJ81_07055 AJ81_07055 tsaD tsaD AJ81_07310 AJ81_07310 AJ81_07370 AJ81_07370 AJ81_07640 AJ81_07640 truA truA fmt fmt mnmG mnmG dtd dtd queH queH gid gid csrA csrA AJ81_07900 AJ81_07900 AJ81_07910 AJ81_07910 AJ81_07935 AJ81_07935 ileS ileS pnp pnp mnmE mnmE AJ81_04255 AJ81_04255 leuS leuS rlmN rlmN trmB trmB dnaA dnaA uvrB uvrB rimO rimO recA recA rny rny AJ81_04000 AJ81_04000 AJ81_03990 AJ81_03990 AJ81_03970 AJ81_03970 rnhB rnhB AJ81_03670 AJ81_03670 AJ81_03650 AJ81_03650 AJ81_03645 AJ81_03645 AJ81_03600 AJ81_03600 xseA xseA xseB xseB smc smc thrS thrS ruvA ruvA valS valS dnaG dnaG sigA sigA AJ81_03395 AJ81_03395 ybeY ybeY psuG psuG alaS alaS nfo nfo dnaJ dnaJ AJ81_03040 AJ81_03040 AJ81_02850 AJ81_02850 argS argS AJ81_02775 AJ81_02775 lexA lexA AJ81_02315 AJ81_02315 uvrA uvrA AJ81_02365 AJ81_02365 AJ81_02370 AJ81_02370 AJ81_02560 AJ81_02560 tyrS tyrS AJ81_02690 AJ81_02690 AJ81_02695 AJ81_02695 AJ81_04730 AJ81_04730 asnC asnC ruvB ruvB AJ81_02145 AJ81_02145 dnaX dnaX
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AJ81_01970Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (305 aa)
AJ81_01965DNA-directed DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (843 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (306 aa)
rbfARibosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (118 aa)
mutS2DNA mismatch repair protein MutS; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (766 aa)
gyrBDNA gyrase subunit B; Negatively supercoils closed circular double-stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (631 aa)
AJ81_017802-methylthioadenine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
AJ81_01755Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (254 aa)
AJ81_01725Recombinase XerC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (287 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (197 aa)
AJ81_01660Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa)
AJ81_01615Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (337 aa)
AJ81_01360Phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
AJ81_01345Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (76 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (812 aa)
AJ81_01265Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
AJ81_01260DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
AJ81_01245Recombinase RarA; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
AJ81_01195Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (281 aa)
AJ81_01160Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (335 aa)
AJ81_01100Transposase IS200; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
AJ81_01085threonyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (557 aa)
tmcALHypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (428 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (333 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (421 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (918 aa)
AJ81_00820RNA polymerase subunit sigma-28; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (236 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (396 aa)
priAHypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (733 aa)
glySglycyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (671 aa)
glyQglycyl-tRNA synthase subunit alpha; glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
nusGTranscription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (354 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1172 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1650 aa)
AJ81_00385RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
AJ81_00365DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (367 aa)
AJ81_00350Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
nfiEndonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. (225 aa)
AJ81_00225SAM-dependent methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. (258 aa)
lysSlysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (501 aa)
AJ81_00080RNase H; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
AJ81_00060Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
AJ81_00055Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (722 aa)
AJ81_00035Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
AJ81_00030Ribonucleoside triphosphate reductase; Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; Derived by automated computational analysis using gene prediction method: Protein Homology. (604 aa)
AJ81_02700Metallo-beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (628 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (809 aa)
AJ81_02715Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
AJ81_08000Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
AJ81_08015Topoisomerase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication. (1110 aa)
AJ81_08135Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (414 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (206 aa)
nusBTranscription antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (140 aa)
AJ81_08370tryptophanyl-tRNA synthase; Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (326 aa)
AJ81_08410Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (371 aa)
gltX-2glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (473 aa)
AJ81_08440Competence protein ComEA; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
AJ81_08465Cytidine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
mrnCRibonuclease III; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (139 aa)
AJ81_08485RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (233 aa)
AJ81_08500Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
AJ81_08600Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
AJ81_08700Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
AJ81_08705Transposase IS200; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
AJ81_08720DNA methylase N-4; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (419 aa)
AJ81_0896016S pseudouridylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (241 aa)
AJ81_08985DsrH family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)
AJ81_08990Intracellular sulfur oxidation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)
AJ81_08995Oxidoreductase DsrE; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
AJ81_09005Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family. (79 aa)
AJ81_09195Transposase IS200; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
AJ81_09200Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
rsmH16S rRNA methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (290 aa)
AJ81_09380Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
thiIThiamin biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (363 aa)
pheTphenylalanyl-tRNA synthetase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (788 aa)
pheSphenylalanyl-tRNA synthase subunit alpha; Catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (334 aa)
AJ81_09570Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (240 aa)
AJ81_09595Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (290 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (444 aa)
AJ81_09850Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
rlmH50S rRNA methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (149 aa)
AJ81_09920DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
rimMRibosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (167 aa)
trmDtRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (262 aa)
AJ81_10045Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (247 aa)
AJ81_10155Nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (549 aa)
ligANAD-dependent DNA ligase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (677 aa)
rnpARibonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (123 aa)
AJ81_10370DNA integrity scanning protein DisA; Non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DisA family. (357 aa)
AJ81_10375DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (443 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (302 aa)
AJ81_10425O-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
AJ81_10490DNA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (472 aa)
cysScysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (464 aa)
hisShistidyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
AJ81_10535RNA polymerase sigma 70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (184 aa)
AJ81_10565Deoxycytidylate deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
rnrRibonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (716 aa)
AJ81_10610Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
mnmAThiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (349 aa)
AJ81_10725TatD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
AJ81_10855Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
AJ81_04760S-layer protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
AJ81_05215Ribonuclease H; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
AJ81_05295methylated-DNA-protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (149 aa)
AJ81_05305Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the sigma-70 factor family. (112 aa)
cas2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (87 aa)
cas2-2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (90 aa)
AJ81_05380CRISPR-associated protein Csm3; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
AJ81_05390Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (814 aa)
cas1CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (329 aa)
AJ81_05440CRISPR-associated protein Crm2; Derived by automated computational analysis using gene prediction method: Protein Homology. (796 aa)
ruvCHolliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (163 aa)
polCDNA polymerase III; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1370 aa)
rsmG16S rRNA methyltransferase; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (232 aa)
rsmI16S rRNA methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (226 aa)
AJ81_05520Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (383 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (424 aa)
AJ81_0553516S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (227 aa)
AJ81_05635Ribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
rtcBtRNA-splicing ligase RtcB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RtcB family. (465 aa)
polADNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (892 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (574 aa)
AJ81_05750CRISPR-associated protein Cas5; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
AJ81_05755CRISPR-associated protein Csh2; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
cas2-3CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (87 aa)
cas1-2CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (327 aa)
AJ81_05775CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (162 aa)
recGHelicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (777 aa)
AJ81_06110Transposase IS605; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
AJ81_06130Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (414 aa)
AJ81_06135Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (193 aa)
AJ81_06170CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (170 aa)
cas1-3CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (325 aa)
cas2-4CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (88 aa)
AJ81_06375CTU1/ATPBD3 family protein MJ1478; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TtcA family. (296 aa)
sbcDNuclease SbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (368 aa)
AJ81_06430Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (834 aa)
AJ81_06460Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
AJ81_06530RNA polymerase sigma70 factor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (208 aa)
aspSaspartyl-tRNA synthase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (583 aa)
AJ81_06595tRNA nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (877 aa)
nusATranscription elongation factor NusA; Participates in both transcription termination and antitermination. (344 aa)
AJ81_07055FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
tsaDO-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (329 aa)
AJ81_07310Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (314 aa)
AJ81_07370Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (450 aa)
AJ81_07640Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (244 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (300 aa)
mnmGtRNA uridine 5-carboxymethylaminomethyl modification protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (633 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (149 aa)
queHHypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (187 aa)
gidtRNA (uracil-5-)-methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (429 aa)
csrACarbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (83 aa)
AJ81_07900Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0102 family. (107 aa)
AJ81_07910Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (290 aa)
AJ81_07935Phage-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (911 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (725 aa)
mnmEtRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (450 aa)
AJ81_04255Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
leuSleucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (815 aa)
rlmN50S rRNA methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (342 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (309 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (440 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (658 aa)
rimORibosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (430 aa)
recAProtein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (347 aa)
rnyRibonuclease; Endoribonuclease that initiates mRNA decay. (509 aa)
AJ81_04000Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
AJ81_03990Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
AJ81_03970DNA recombination protein RmuC; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (226 aa)
AJ81_03670Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
AJ81_03650Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
AJ81_03645Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (60 aa)
AJ81_03600Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (499 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (402 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (78 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1183 aa)
thrSthreonyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (639 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (193 aa)
valSvalyl-tRNA synthase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (862 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (558 aa)
sigARNA polymerase sigma factor rpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (367 aa)
AJ81_03395Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
ybeYrRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (140 aa)
psuGPseudouridine-5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (287 aa)
alaSalanyl-tRNA synthase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (868 aa)
nfoEndonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (282 aa)
dnaJMolecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (371 aa)
AJ81_03040Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
AJ81_02850Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
argSarginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
AJ81_02775Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (833 aa)
lexALexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (199 aa)
AJ81_02315Appr-1-p processing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (922 aa)
AJ81_02365Phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
AJ81_02370Peptidase M22; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
AJ81_02560Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (402 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (400 aa)
AJ81_02690Hypothetical protein; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (214 aa)
AJ81_02695Single-stranded DNA exonuclease RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (974 aa)
AJ81_04730Dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (317 aa)
asnCasparaginyl-tRNA synthase; Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (349 aa)
AJ81_02145Chromosome segregation protein SMC; May be involved in recombinational repair of damaged DNA. (515 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (469 aa)
Your Current Organism:
Pseudothermotoga hypogea
NCBI taxonomy Id: 1123384
Other names: P. hypogea DSM 11164 = NBRC 106472, Pseudothermotoga hypogea DSM 11164, Pseudothermotoga hypogea DSM 11164 = NBRC 106472, Pseudothermotoga hypogea NBRC 106472, Pseudothermotoga hypogea NBRC 106472 = DSM 11164, Thermotoga hypogea DSM 11164, Thermotoga hypogea DSM 11164 = NBRC 106472, Thermotoga hypogea NBRC 106472
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