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glmU glmU AJ81_00855 AJ81_00855 AJ81_01125 AJ81_01125 AJ81_01250 AJ81_01250 murA murA glmS glmS AJ81_02140 AJ81_02140 AJ81_03475 AJ81_03475 AJ81_03610 AJ81_03610 AJ81_03690 AJ81_03690 AJ81_04540 AJ81_04540 AJ81_04795 AJ81_04795 AJ81_05080 AJ81_05080 murQ murQ pgi pgi AJ81_05230 AJ81_05230 AJ81_06745 AJ81_06745 glgC glgC AJ81_06960 AJ81_06960 glmM glmM murB murB AJ81_07825 AJ81_07825 AJ81_08650 AJ81_08650 AJ81_08655 AJ81_08655 AJ81_08730 AJ81_08730 AJ81_09395 AJ81_09395 AJ81_09400 AJ81_09400 AJ81_10475 AJ81_10475
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glmUN-acetylglucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (448 aa)
AJ81_00855Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
AJ81_01125Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
AJ81_01250UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (606 aa)
AJ81_02140Phosphomannomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
AJ81_03475N-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
AJ81_03610UDP-N-acetyl-D-glucosamine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (434 aa)
AJ81_03690alpha-N-arabinofuranosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
AJ81_04540Galactose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
AJ81_04795Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
AJ81_05080Glycoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
murQN-acetylmuramic acid-6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (299 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (451 aa)
AJ81_05230Glycoside hydrolase family 3; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
AJ81_06745Glucose-1-phosphate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (368 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (420 aa)
AJ81_06960Glycoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (604 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. (429 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (280 aa)
AJ81_07825Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
AJ81_08650Galactokinase; Catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GHMP kinase family. GalK subfamily. (361 aa)
AJ81_08655Galactose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
AJ81_08730UDP-N-acetylglucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (353 aa)
AJ81_09395UDP-N-acetylglucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (359 aa)
AJ81_09400Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
AJ81_10475Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (334 aa)
Your Current Organism:
Pseudothermotoga hypogea
NCBI taxonomy Id: 1123384
Other names: P. hypogea DSM 11164 = NBRC 106472, Pseudothermotoga hypogea DSM 11164, Pseudothermotoga hypogea DSM 11164 = NBRC 106472, Pseudothermotoga hypogea NBRC 106472, Pseudothermotoga hypogea NBRC 106472 = DSM 11164, Thermotoga hypogea DSM 11164, Thermotoga hypogea DSM 11164 = NBRC 106472, Thermotoga hypogea NBRC 106472
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