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thiI thiI AJ81_01740 AJ81_01740 AJ81_04265 AJ81_04265 moaC moaC AJ81_06280 AJ81_06280 AJ81_08985 AJ81_08985 AJ81_08995 AJ81_08995 AJ81_10255 AJ81_10255 AJ81_10265 AJ81_10265 mnmA mnmA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
thiIThiamin biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (363 aa)
AJ81_01740Molybdenum cofactor biosynthesis protein MoaB; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
AJ81_04265Adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
moaCMolybdenum cofactor biosynthesis protein MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (157 aa)
AJ81_06280Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (302 aa)
AJ81_08985DsrH family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)
AJ81_08995Oxidoreductase DsrE; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
AJ81_10255Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
AJ81_10265Cysteine desulfarase; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
mnmAThiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (349 aa)
Your Current Organism:
Pseudothermotoga hypogea
NCBI taxonomy Id: 1123384
Other names: P. hypogea DSM 11164 = NBRC 106472, Pseudothermotoga hypogea DSM 11164, Pseudothermotoga hypogea DSM 11164 = NBRC 106472, Pseudothermotoga hypogea NBRC 106472, Pseudothermotoga hypogea NBRC 106472 = DSM 11164, Thermotoga hypogea DSM 11164, Thermotoga hypogea DSM 11164 = NBRC 106472, Thermotoga hypogea NBRC 106472
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