(8 nodes) Proline metabolic process, and Oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor network (Halomonas sp. QHL1)

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Your Input:
	proA	Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (435 aa)
	OJA04898.1	Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1063 aa)
	OJA05832.1	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (450 aa)
	OJA06406.1	Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
	proB	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (379 aa)
	proC	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (274 aa)
	OJA06841.1	Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (1480 aa)
	OJA06842.1	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)

Your Current Organism:

Halomonas sp. QHL1

NCBI taxonomy Id: 1123773
Other names: H. sp. QHL1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OJA04898.1	OJA05832.1	QHL1GM_05545	QHL1GM_10750	Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.888
OJA04898.1	OJA06406.1	QHL1GM_05545	QHL1GM_13945	Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.873
OJA04898.1	OJA06841.1	QHL1GM_05545	QHL1GM_16300	Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.939
OJA04898.1	OJA06842.1	QHL1GM_05545	QHL1GM_16305	Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.804
OJA04898.1	proA	QHL1GM_05545	QHL1GM_04940	Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	0.856
OJA04898.1	proB	QHL1GM_05545	QHL1GM_14140	Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.868
OJA04898.1	proC	QHL1GM_05545	QHL1GM_14545	Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.	0.891
OJA05832.1	OJA04898.1	QHL1GM_10750	QHL1GM_05545	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.888
OJA05832.1	OJA06406.1	QHL1GM_10750	QHL1GM_13945	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.942
OJA05832.1	OJA06841.1	QHL1GM_10750	QHL1GM_16300	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OJA05832.1	OJA06842.1	QHL1GM_10750	QHL1GM_16305	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.965
OJA05832.1	proA	QHL1GM_10750	QHL1GM_04940	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	0.934
OJA05832.1	proB	QHL1GM_10750	QHL1GM_14140	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.631
OJA06406.1	OJA04898.1	QHL1GM_13945	QHL1GM_05545	Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.873
OJA06406.1	OJA05832.1	QHL1GM_13945	QHL1GM_10750	Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.942
OJA06406.1	OJA06841.1	QHL1GM_13945	QHL1GM_16300	Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.991
OJA06406.1	OJA06842.1	QHL1GM_13945	QHL1GM_16305	Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.951
OJA06406.1	proA	QHL1GM_13945	QHL1GM_04940	Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.	0.941
OJA06406.1	proB	QHL1GM_13945	QHL1GM_14140	Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.	0.645
OJA06841.1	OJA04898.1	QHL1GM_16300	QHL1GM_05545	Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.	0.939