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OJA04023.1 OJA04023.1 betA betA betB betB OJA04294.1 OJA04294.1 OJA04335.1 OJA04335.1 OJA07311.1 OJA07311.1 srkA srkA serC serC OJA04446.1 OJA04446.1 gcvP gcvP gcvH gcvH gcvT gcvT OJA04491.1 OJA04491.1 ectA ectA OJA04514.1 OJA04514.1 ectC ectC pqqC pqqC trpA trpA trpB trpB asd asd pepQ pepQ OJA05115.1 OJA05115.1 trpA-2 trpA-2 trpB-2 trpB-2 OJA05216.1 OJA05216.1 OJA05286.1 OJA05286.1 OJA05340.1 OJA05340.1 OJA05400.1 OJA05400.1 OJA05401.1 OJA05401.1 OJA05403.1 OJA05403.1 OJA05404.1 OJA05404.1 OJA05405.1 OJA05405.1 OJA05458.1 OJA05458.1 OJA05566.1 OJA05566.1 thrB thrB OJA05579.1 OJA05579.1 OJA05596.1 OJA05596.1 OJA05678.1 OJA05678.1 OJA05771.1 OJA05771.1 OJA05872.1 OJA05872.1 OJA05954.1 OJA05954.1 OJA05971.1 OJA05971.1 OJA07425.1 OJA07425.1 OJA06154.1 OJA06154.1 ilvA ilvA OJA07438.1 OJA07438.1 gpmI gpmI OJA06578.1 OJA06578.1 glyA glyA OJA06580.1 OJA06580.1 OJA06581.1 OJA06581.1 OJA06582.1 OJA06582.1 OJA06583.1 OJA06583.1 OJA06585.1 OJA06585.1 OJA06590.1 OJA06590.1 OJA06639.1 OJA06639.1 OJA06640.1 OJA06640.1 OJA06676.1 OJA06676.1 OJA06852.1 OJA06852.1 OJA06951.1 OJA06951.1 OJA07123.1 OJA07123.1 OJA07142.1 OJA07142.1 glyA-2 glyA-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OJA04023.1Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
betACholine dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (557 aa)
betBBetaine-aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. (489 aa)
OJA04294.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
OJA04335.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)
OJA07311.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (586 aa)
srkAStress response serine/threonine protein kinase YihE; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (324 aa)
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (367 aa)
OJA04446.1Zinc-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
gcvPGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (964 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gcvTGlycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
OJA04491.1Glycerate dehydrogenase; Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (313 aa)
ectADiaminobutyrate acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (192 aa)
OJA04514.1Diaminobutyrate--2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (422 aa)
ectCL-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (129 aa)
pqqCPyrroloquinoline quinone biosynthesis protein PqqC; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. (234 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (415 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (370 aa)
pepQXaa-Pro dipeptidase; Splits dipeptides with a prolyl residue in the C-terminal position. (432 aa)
OJA05115.1Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (348 aa)
trpA-2Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (272 aa)
trpB-2Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (409 aa)
OJA05216.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (315 aa)
OJA05286.1Choline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
OJA05340.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa)
OJA05400.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (477 aa)
OJA05401.1NAD-dependent succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (498 aa)
OJA05403.1N-alpha-acetyl diaminobutyric acid deacetylase DoeB; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
OJA05404.1Ectoine hydrolase DoeA; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
OJA05405.1Glyoxylate/hydroxypyruvate reductase A; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
OJA05458.1Serine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
OJA05566.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (379 aa)
thrBHomoserine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudomonas-type ThrB family. (319 aa)
OJA05579.1Ectoine hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
OJA05596.1CDP-diacylglycerol--serine O-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (295 aa)
OJA05678.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (487 aa)
OJA05771.1Xaa-Pro aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
OJA05872.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (485 aa)
OJA05954.1D-3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (414 aa)
OJA05971.1Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
OJA07425.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
OJA06154.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
ilvAPLP-dependent threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (504 aa)
OJA07438.1Xaa-Pro aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M24B family. (446 aa)
gpmIPhosphoglycerate mutase (2,3-diphosphoglycerate-independent); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (525 aa)
OJA06578.1Rieske (2Fe-2S) protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (437 aa)
OJA06580.1Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
OJA06581.1Sarcosine oxidase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
OJA06582.1Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (1016 aa)
OJA06583.1Sarcosine oxidase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
OJA06585.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (460 aa)
OJA06590.1Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (395 aa)
OJA06639.1Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
OJA06640.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
OJA06676.1ArsC family reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. (113 aa)
OJA06852.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (416 aa)
OJA06951.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
OJA07123.1Succinylglutamate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
OJA07142.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (421 aa)
Your Current Organism:
Halomonas sp. QHL1
NCBI taxonomy Id: 1123773
Other names: H. sp. QHL1
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