STRINGSTRING
ALE01134.1 ALE01134.1 ALE01152.1 ALE01152.1 ALE01195.1 ALE01195.1 ALE01206.1 ALE01206.1 ALE01215.1 ALE01215.1 ALE01216.1 ALE01216.1 ALE01229.1 ALE01229.1 gcvT gcvT gcvH gcvH gcvP gcvP ALE01237.1 ALE01237.1 ALE01238.1 ALE01238.1 ALE01239.1 ALE01239.1 ALE01240.1 ALE01240.1 ALE01241.1 ALE01241.1 ALE01243.1 ALE01243.1 ALE01244.1 ALE01244.1 ALE01245.1 ALE01245.1 ALE01246.1 ALE01246.1 ALE01247.1 ALE01247.1 dsbB dsbB ALE01249.1 ALE01249.1 adk adk ALE01255.1 ALE01255.1 cysS cysS proC proC ALE01297.1 ALE01297.1 ALE01298.1 ALE01298.1 proA proA ALE01399.1 ALE01399.1 tdk tdk ALE01430.1 ALE01430.1 ppnP ppnP tmk tmk ALE01448.1 ALE01448.1 ALE01468.1 ALE01468.1 ALE01469.1 ALE01469.1 ALE01471.1 ALE01471.1 ALE01472.1 ALE01472.1 ALE01473.1 ALE01473.1 ALE01474.1 ALE01474.1 ALE01475.1 ALE01475.1 ALE01476.1 ALE01476.1 ALE01477.1 ALE01477.1 ALE01478.1 ALE01478.1 ALE01479.1 ALE01479.1 ALE01480.1 ALE01480.1 ALE01481.1 ALE01481.1 purN purN purM purM ALE01517.1 ALE01517.1 ALE01547.1 ALE01547.1 fmt fmt ALE01561.1 ALE01561.1 ALE01569.1 ALE01569.1 ahcY ahcY metK metK purL purL proB proB ilvA ilvA ALE01708.1 ALE01708.1 ALE01715.1 ALE01715.1 purA purA glnA glnA ALE01824.1 ALE01824.1 ALE01827.1 ALE01827.1 gmk gmk thyA thyA glyA glyA ALE01917.1 ALE01917.1 psuG psuG ALE01941.1 ALE01941.1 ALE01943.1 ALE01943.1 ALE02709.1 ALE02709.1 ALE01960.1 ALE01960.1 ALE02010.1 ALE02010.1 ALE02027.1 ALE02027.1 ALE02028.1 ALE02028.1 ALE02029.1 ALE02029.1 deoA deoA deoB deoB ALE02033.1 ALE02033.1 ALE02034.1 ALE02034.1 ALE02063.1 ALE02063.1 ALE02733.1 ALE02733.1 ALE02065.1 ALE02065.1 ALE02066.1 ALE02066.1 ALE02067.1 ALE02067.1 ALE02068.1 ALE02068.1 folD folD ALE02075.1 ALE02075.1 ALE02076.1 ALE02076.1 ALE02077.1 ALE02077.1 ALE02078.1 ALE02078.1 ALE02079.1 ALE02079.1 ALE02080.1 ALE02080.1 ALE02081.1 ALE02081.1 ALE02082.1 ALE02082.1 ALE02122.1 ALE02122.1 ALE02126.1 ALE02126.1 ALE02755.1 ALE02755.1 ALE02200.1 ALE02200.1 upp upp purE purE purK purK folD-2 folD-2 ALE02269.1 ALE02269.1 carB carB carA carA glmS glmS apt apt surE surE guaA guaA ALE02337.1 ALE02337.1 purH purH ALE02388.1 ALE02388.1 ALE02389.1 ALE02389.1 ALE02392.1 ALE02392.1 ALE02406.1 ALE02406.1 pyrE pyrE ALE02420.1 ALE02420.1 purF purF ALE02423.1 ALE02423.1 ALE02436.1 ALE02436.1 ALE02438.1 ALE02438.1 ALE02455.1 ALE02455.1 fhs fhs ALE02479.1 ALE02479.1 ALE02480.1 ALE02480.1 ALE02481.1 ALE02481.1 ALE02482.1 ALE02482.1 ALE02483.1 ALE02483.1 ALE02484.1 ALE02484.1 ALE02485.1 ALE02485.1 ALE02486.1 ALE02486.1 ALE02487.1 ALE02487.1 purD purD pyrB pyrB purC purC pyrC pyrC pyrD pyrD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ALE01134.1Methylamine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (691 aa)
ALE01152.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
ALE01195.1Trimethylamine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the trimethylamine methyltransferase family. (513 aa)
ALE01206.1Enterotoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
ALE01215.1Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the trimethylamine methyltransferase family. (506 aa)
ALE01216.1Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (804 aa)
ALE01229.1Serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (459 aa)
gcvTGlycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (950 aa)
ALE01237.1Creatininase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
ALE01238.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
ALE01239.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
ALE01240.15-oxoprolinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1207 aa)
ALE01241.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
ALE01243.1Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
ALE01244.1Sarcosine oxidase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
ALE01245.1Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (1012 aa)
ALE01246.1Sarcosine oxidase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
ALE01247.1Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
dsbBDisulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (170 aa)
ALE01249.1Cyclopropane fatty acyl phospholipid synthase; Catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (217 aa)
ALE01255.1HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
cysScysteinyl-tRNA synthetase; Catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (459 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (276 aa)
ALE01297.1Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (805 aa)
ALE01298.1Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the trimethylamine methyltransferase family. (518 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa)
ALE01399.1Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1210 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
ALE01430.1Thiol-disulfide interchange protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (239 aa)
ppnPHypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (103 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (205 aa)
ALE01448.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
ALE01468.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
ALE01469.1Iron-sulfur protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
ALE01471.1Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
ALE01472.1Ethanolamine utilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
ALE01473.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
ALE01474.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (472 aa)
ALE01475.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
ALE01476.1Protein glxC; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
ALE01477.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (440 aa)
ALE01478.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (437 aa)
ALE01479.1Homoserine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AB hydrolase superfamily. MetX family. (337 aa)
ALE01480.1tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)
ALE01481.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (306 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (202 aa)
purMPhosphoribosylaminoimidazole synthetase; Phage-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
ALE01517.1Potassium transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
ALE01547.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (309 aa)
ALE01561.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (299 aa)
ALE01569.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (452 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (470 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (377 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1279 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (257 aa)
ilvAL-threonine dehydratase biosynthetic IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (497 aa)
ALE01708.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
ALE01715.1Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). (234 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (438 aa)
glnAForms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
ALE01824.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (822 aa)
ALE01827.1Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. (372 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (227 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
ALE01917.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (359 aa)
psuGPseudouridine-5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (306 aa)
ALE01941.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
ALE01943.15'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family. (545 aa)
ALE02709.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (308 aa)
ALE01960.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
ALE02010.1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (337 aa)
ALE02027.1Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (130 aa)
ALE02028.1Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (267 aa)
ALE02029.1Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate. (348 aa)
deoAThymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (451 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (404 aa)
ALE02033.1Adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
ALE02034.1Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
ALE02063.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (811 aa)
ALE02733.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (189 aa)
ALE02065.1Sarcosine oxidase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (987 aa)
ALE02066.1Sarcosine oxidase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
ALE02067.1Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (420 aa)
ALE02068.1Monomeric sarcosine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa)
folDTetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (277 aa)
ALE02075.1Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (766 aa)
ALE02076.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
ALE02077.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (445 aa)
ALE02078.1GXGXG motif-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
ALE02079.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
ALE02080.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (492 aa)
ALE02081.1XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
ALE02082.1Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
ALE02122.15'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
ALE02126.1Cytochrome C4; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
ALE02755.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (271 aa)
ALE02200.1Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (162 aa)
purKPhosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (360 aa)
folD-2Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (277 aa)
ALE02269.1Glutamate synthase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (479 aa)
carBCarbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1069 aa)
carACarbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
glmSGlucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (615 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (175 aa)
surEStationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (248 aa)
guaAGMP synthase; Catalyzes the synthesis of GMP from XMP. (524 aa)
ALE02337.1Xanthine permease; High-affinity transporter for xanthine; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
purHIMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
ALE02388.1Dimethylglycine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (841 aa)
ALE02389.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (99 aa)
ALE02392.15-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (184 aa)
ALE02406.1Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (454 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (213 aa)
ALE02420.1Folylpolyglutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (505 aa)
ALE02423.1Catalyzes the conversion of O-succinylhomoserine into homocysteine; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
ALE02436.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1505 aa)
ALE02438.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (162 aa)
ALE02455.1Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
fhsFormate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (559 aa)
ALE02479.1Trimethylamine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the trimethylamine methyltransferase family. (515 aa)
ALE02480.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (646 aa)
ALE02481.1Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
ALE02482.1Methyltetrahydrofolate:corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
ALE02483.1Methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
ALE02484.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
ALE02485.15-methyltetrahydrofolate--homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
ALE02486.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
ALE02487.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
purDPhosphoribosylamine--glycine ligase; Catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (421 aa)
pyrBAspartate carbamoyltransferase; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (319 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (349 aa)
pyrDDiguanylate cyclase; Catalyzes the conversion of dihydroorotate to orotate. (309 aa)
Your Current Organism:
Thioglobus singularis
NCBI taxonomy Id: 1125411
Other names: C. Thioglobus singularis PS1, Candidatus Thioglobus singularis PS1, gamma proteobacterium GSO-PS1, sulfur-oxidizing bacterium GSO-PS1
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