(22 nodes) Lysine degradation network (Rhizobium sp. NT26)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	NT26_0120	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
	NT26_0121	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (737 aa)
	gabD	Succinate-semialdehyde dehydrogenase [NADP+]; Belongs to the aldehyde dehydrogenase family. (484 aa)
	NT26_0738	Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the LDH2/MDH2 oxidoreductase family. (345 aa)
	lpD	Dihydrolipoyl dehydrogenase; Function of strongly homologous gene; enzyme. (481 aa)
	dat	D-alanine aminotransferase. (287 aa)
	alkH	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (465 aa)
	gabD-2	Succinate-semialdehyde dehydrogenase [NADP+]; Belongs to the aldehyde dehydrogenase family. (490 aa)
	betB-2	Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (489 aa)
	NT26_2571	Putative Aldehyde dehydrogenase (NAD(+)); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (475 aa)
	lpdV	Homologs of previously reported genes of unknown function. (464 aa)
	gcdH	glutaryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (395 aa)
	gabD-3	Succinate-semialdehyde dehydrogenase [NADP+]. (496 aa)
	Hibch	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial. (353 aa)
	NT26_3018	Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (256 aa)
	NT26_3104	Putative lysine 2,3-aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (349 aa)
	NT26_3111	Aldehyde dehydrogenase family 7 member A1 homolog; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. (513 aa)
	lpd	Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (468 aa)
	sucB	Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (414 aa)
	phbA	Acetyl-CoA acetyltransferase with thiolase domain (Acetoacetyl-CoA thiolase); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	NT26_3632	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
	fadB	Putative enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)

Your Current Organism:

Rhizobium sp. NT26

NCBI taxonomy Id: 1125847
Other names: R. sp. NT-26, Rhizobium sp. NT-26, arsenite-oxidising bacterium NT-26

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hibch	NT26_0120	NT26_2884	NT26_0120	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	0.591
Hibch	NT26_0121	NT26_2884	NT26_0121	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.923
Hibch	NT26_3632	NT26_2884	NT26_3632	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.591
Hibch	fadB	NT26_2884	NT26_4301	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Putative enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.925
Hibch	gcdH	NT26_2884	NT26_2878	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	glutaryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.953
Hibch	phbA	NT26_2884	NT26_3604	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Acetyl-CoA acetyltransferase with thiolase domain (Acetoacetyl-CoA thiolase); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	0.591
NT26_0120	Hibch	NT26_0120	NT26_2884	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	0.591
NT26_0120	NT26_0121	NT26_0120	NT26_0121	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.999
NT26_0120	NT26_3632	NT26_0120	NT26_3632	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.900
NT26_0120	fadB	NT26_0120	NT26_4301	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	Putative enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.598
NT26_0120	gcdH	NT26_0120	NT26_2878	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	glutaryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.414
NT26_0120	phbA	NT26_0120	NT26_3604	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	Acetyl-CoA acetyltransferase with thiolase domain (Acetoacetyl-CoA thiolase); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	0.917
NT26_0120	sucB	NT26_0120	NT26_3488	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.814
NT26_0121	Hibch	NT26_0121	NT26_2884	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	0.923
NT26_0121	NT26_0120	NT26_0121	NT26_0120	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	0.999
NT26_0121	NT26_2571	NT26_0121	NT26_2571	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative Aldehyde dehydrogenase (NAD(+)); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.914
NT26_0121	NT26_3111	NT26_0121	NT26_3111	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Aldehyde dehydrogenase family 7 member A1 homolog; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family.	0.914
NT26_0121	NT26_3632	NT26_0121	NT26_3632	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.997
NT26_0121	alkH	NT26_0121	NT26_1664	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.914
NT26_0121	betB-2	NT26_0121	NT26_2456	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.914