(32 nodes) Benzoate degradation network (Rhizobium sp. NT26)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	NT26_0120	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
	NT26_0121	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (737 aa)
	NT26_0169	Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (688 aa)
	NT26_0175	Putative carboxymuconolactone decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (183 aa)
	NT26_0602	Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (188 aa)
	NT26_0603	Function of strongly homologous gene; enzyme. (279 aa)
	NT26_0688	Homologs of previously reported genes of unknown function. (367 aa)
	NT26_0822	Putative ring-cleaving dioxygenase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (286 aa)
	NT26_1310	Amidohydrolase 2. (287 aa)
	ehhadh	Peroxisomal bifunctional enzyme [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; 3-hydroxyacyl-CoA dehydrogenase]. (646 aa)
	fabG-3	3-oxoacyl-[acyl-carrier-protein] reductase. (251 aa)
	NT26_2790	Putative tautomerase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 4-oxalocrotonate tautomerase family. (72 aa)
	gcdH	glutaryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (395 aa)
	Hibch	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial. (353 aa)
	NT26_3184	Homologs of previously reported genes of unknown function. (245 aa)
	NT26_3185	Metapyrocatechase; catechol 2,3-dioxygenase. (318 aa)
	ligK	4-carboxy-4-hydroxy-2-oxoadipate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (223 aa)
	NT26_3187	Homologs of previously reported genes of unknown function. (342 aa)
	hbdA	3-hydroxybutyryl-CoA dehydrogenase (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD); Function of strongly homologous gene; enzyme. (294 aa)
	phbA	Acetyl-CoA acetyltransferase with thiolase domain (Acetoacetyl-CoA thiolase); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
	NT26_3632	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
	pcaF	Beta-ketoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
	scoB	3-oxoadipate CoA-transferase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (233 aa)
	scoA	3-oxoadipate CoA-transferase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (235 aa)
	pcaB	3-carboxy-cis,cis-muconate cycloisomerase protein. (352 aa)
	pcaG	Protocatechuate 3,4-dioxygenase alpha chain. (205 aa)
	pcaH	Protocatechuate 3,4-dioxygenase beta chain. (246 aa)
	pcaC	4-carboxymuconolactone decarboxylase. (146 aa)
	pcaD	Beta-ketoadipate enol-lactone hydrolase protein. (265 aa)
	phbH	4-hydroxybenzoate hydroxylase (4-hydroxybenzoate-3-monooxygenase); Function of strongly homologous gene; enzyme. (389 aa)
	ehhadh-2	Peroxisomal bifunctional enzyme [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; 3-hydroxyacyl-CoA dehydrogenase]; Belongs to the enoyl-CoA hydratase/isomerase family. (658 aa)
	fadB	Putative enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)

Your Current Organism:

Rhizobium sp. NT26

NCBI taxonomy Id: 1125847
Other names: R. sp. NT-26, Rhizobium sp. NT-26, arsenite-oxidising bacterium NT-26

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hibch	NT26_0120	NT26_2884	NT26_0120	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	0.591
Hibch	NT26_0121	NT26_2884	NT26_0121	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.923
Hibch	NT26_0169	NT26_2884	NT26_0169	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.	0.922
Hibch	NT26_0603	NT26_2884	NT26_0603	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Function of strongly homologous gene; enzyme.	0.800
Hibch	NT26_0688	NT26_2884	NT26_0688	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Homologs of previously reported genes of unknown function.	0.806
Hibch	NT26_1310	NT26_2884	NT26_1310	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Amidohydrolase 2.	0.800
Hibch	NT26_3187	NT26_2884	NT26_3187	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Homologs of previously reported genes of unknown function.	0.806
Hibch	NT26_3632	NT26_2884	NT26_3632	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.591
Hibch	ehhadh	NT26_2884	NT26_2058	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Peroxisomal bifunctional enzyme [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; 3-hydroxyacyl-CoA dehydrogenase].	0.918
Hibch	ehhadh-2	NT26_2884	NT26_3988	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Peroxisomal bifunctional enzyme [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; 3-hydroxyacyl-CoA dehydrogenase]; Belongs to the enoyl-CoA hydratase/isomerase family.	0.922
Hibch	fadB	NT26_2884	NT26_4301	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Putative enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the enoyl-CoA hydratase/isomerase family.	0.925
Hibch	gcdH	NT26_2884	NT26_2878	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	glutaryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.953
Hibch	hbdA	NT26_2884	NT26_3415	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	3-hydroxybutyryl-CoA dehydrogenase (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD); Function of strongly homologous gene; enzyme.	0.936
Hibch	pcaF	NT26_2884	NT26_3740	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Beta-ketoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.591
Hibch	phbA	NT26_2884	NT26_3604	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	Acetyl-CoA acetyltransferase with thiolase domain (Acetoacetyl-CoA thiolase); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	0.591
NT26_0120	Hibch	NT26_0120	NT26_2884	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial.	0.591
NT26_0120	NT26_0121	NT26_0120	NT26_0121	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.999
NT26_0120	NT26_0169	NT26_0120	NT26_0169	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family.	0.997
NT26_0120	NT26_3632	NT26_0120	NT26_3632	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.	0.900
NT26_0120	ehhadh	NT26_0120	NT26_2058	Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family.	Peroxisomal bifunctional enzyme [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; 3-hydroxyacyl-CoA dehydrogenase].	0.997