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| | tme | NADP-dependent malic enzyme (NADP-ME); Function experimentally demonstrated in the studied genus; enzyme. (759 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase (SDAP); Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (398 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the transferase hexapeptide repeat family. (284 aa) |
| | pgi | Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family. (541 aa) |
| | NT26_0071 | Dihydrodipicolinate synthetase-like protein; Function of strongly homologous gene; enzyme; Belongs to the DapA family. (308 aa) |
| | argD | Acetylornithine transaminase (NAcOATase and DapATase), PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (398 aa) |
| | NT26_0120 | Putative acyl-CoA ketothiolase / acetyl-CoA acyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa) |
| | NT26_0121 | 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (737 aa) |
| | NT26_0136 | Mandelate racemase-like enolase, enolase superfamily domain protein; Function of strongly homologous gene; enzyme; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (425 aa) |
| | NT26_0137 | Short-chain Dehydrogenase/Reductase (SDR) family protein, UcpA-like NADH-dependent dehydrogenase; Function of strongly homologous gene; enzyme. (244 aa) |
| | dapA | Dihydrodipicolinate synthase (DHDPS); Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (305 aa) |
| | NT26_0157 | Putative Dihydrodipicolinate reductase (DHPR/DapB); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DapB family. (249 aa) |
| | NT26_0168 | acyl-CoA ligase; Function of strongly homologous gene; enzyme. (690 aa) |
| | NT26_0169 | Short chain enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (688 aa) |
| | NT26_0170 | acyl-CoA ligase; Function of strongly homologous gene; enzyme. (696 aa) |
| | NT26_0175 | Putative carboxymuconolactone decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (183 aa) |
| | folD | Bifunctional protein folD 2 [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (299 aa) |
| | edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (605 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (232 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (490 aa) |
| | glnA | Glutamine synthetase protein. (468 aa) |
| | aceA | Isocitrate lyase. (429 aa) |
| | NT26_0293 | Putative gluconokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (179 aa) |
| | glnA-2 | Glutamine synthetase. (452 aa) |
| | gabD | Succinate-semialdehyde dehydrogenase [NADP+]; Belongs to the aldehyde dehydrogenase family. (484 aa) |
| | adhA | Alcohol dehydrogenase. (342 aa) |
| | NT26_0386 | Homologs of previously reported genes of unknown function. (291 aa) |
| | glcD | Glycolate oxidase subunit glcD. (479 aa) |
| | NT26_0398 | FAD linked oxidase domain protein. (400 aa) |
| | glcF | Glycolate oxidase subunit, (Fe-S)protein, GlcF; Function of homologous gene experimentally demonstrated in an other organism; putative enzyme. (432 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (206 aa) |
| | thrB | Homoserine kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pseudomonas-type ThrB family. (324 aa) |
| | thrC | Threonine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (468 aa) |
| | NT26_0542 | Hydrolase. (204 aa) |
| | ppdK | Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (896 aa) |
| | NT26_0567 | Putative IolI protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (277 aa) |
| | NT26_0602 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (188 aa) |
| | NT26_0603 | Function of strongly homologous gene; enzyme. (279 aa) |
| | phtD | 4,5-dihydroxyphthalate decarboxylase (DHP decarboxylase); Function of strongly homologous gene; enzyme. (327 aa) |
| | NT26_0615 | Putative Flavin-containing monooxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (642 aa) |
| | NT26_0628 | Nitrite reductase, copper-containing precursor; Function of strongly homologous gene; enzyme; Belongs to the multicopper oxidase family. (357 aa) |
| | cbbE | Ribulose-phosphate 3-epimerase (Pentose-5-phosphate 3-epimerase) (PPE) (R5P3E); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa) |
| | cbbS | Ribulose bisphosphate carboxylase small chain (RuBisCO small subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (129 aa) |
| | cbbL | Ribulose bisphosphate carboxylase large chain (RuBisCO large subunit); RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (487 aa) |
| | cbbA | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (371 aa) |
| | cbbT | Transketolase (TK); Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa) |
| | cbbP | Phosphoribulokinase (Phosphopentokinase) (PRKase) (PRK); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (292 aa) |
| | fbp | Fructose-1,6-bisphosphatase class 1; Belongs to the FBPase class 1 family. (344 aa) |
| | leuB | Putative 3-isopropylmalate dehydrogenase oxidoreductase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (360 aa) |
| | NT26_0688 | Homologs of previously reported genes of unknown function. (367 aa) |
| | icd | Isocitrate dehydrogenase [NADP] (Oxalosuccinate decarboxylase) (IDH) (NADP(+)-specific ICDH) (IDP); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (407 aa) |
| | NT26_0697 | Homologs of previously reported genes of unknown function. (235 aa) |
| | NT26_0709 | Alpha/beta hydrolase fold. (314 aa) |
| | NT26_0720 | Homologs of previously reported genes of unknown function. (285 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (253 aa) |
| | cysD | Putative Sulfate adenylate transferase, subunit 2 (NodP-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (317 aa) |
| | cysN | Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (495 aa) |
| | NT26_0822 | Putative ring-cleaving dioxygenase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (286 aa) |
| | acyP | Acylphosphatase. (94 aa) |
| | dapA-2 | Putative dihydrodipicolinate synthetase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the DapA family. (301 aa) |
| | NT26_0880 | Aldehyde oxidase and xanthine dehydrogenase molybdopterin binding. (750 aa) |
| | NT26_0881 | Putative xanthine dehydrogenase (YagS-like), FAD binding subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (338 aa) |
| | NT26_0882 | Putative xanthine dehydrogenase YagT-like, iron-sulfur binding subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (173 aa) |
| | NT26_0955 | Glutamine synthetase catalytic region. (443 aa) |
| | thcD | Rhodocoxin reductase. (405 aa) |
| | hpcH | 4-hydroxy-2-oxo-heptane-1,7-dioate aldolase; Belongs to the HpcH/HpaI aldolase family. (267 aa) |
| | NT26_1026 | Monooxygenase, FAD-binding protein. (539 aa) |
| | dapA-3 | Dihydrodipicolinate synthase protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ALAD family. (337 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (429 aa) |
| | NT26_1282 | Putative glyoxalase I family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (134 aa) |
| | NT26_1310 | Amidohydrolase 2. (287 aa) |
| | accC | Acetyl CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | accB | acetyl-CoA carboxylase, biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa) |
| | cysQ | 3'(2'),5'-bisphosphate nucleotidase cysQ; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (268 aa) |
| | sseA | Thiosulfate sulfurtransferase protein. (291 aa) |
| | cys | Cysteine synthase 1. (345 aa) |
| | gltA | Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family. (429 aa) |
| | eno | Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (424 aa) |
| | pdhA | Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (348 aa) |
| | pdhB | Pyruvate dehydrogenase E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (476 aa) |
| | pdhC | Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (457 aa) |
| | lpD | Dihydrolipoyl dehydrogenase; Function of strongly homologous gene; enzyme. (481 aa) |
| | cysG | Uroporphyrin-III C-methyltransferase protein; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (478 aa) |
| | NT26_1644 | Sulfite/ferredoxin-nitrite reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (556 aa) |
| | alkH | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (465 aa) |
| | dme | NAD-dependent malic enzyme. (767 aa) |
| | fghA | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (279 aa) |
| | adhC | S-(hydroxymethyl)glutathione dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa) |
| | tpiA | Triosephosphate isomerase (TIM) (Triose-phosphate isomerase); Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (256 aa) |
| | glnA-3 | Glutamine synthetase I (Glutamate--ammonia ligase I) (GSI); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (469 aa) |
| | cbbE-2 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (224 aa) |
| | rpiA | Ribose 5-phosphate isomerase (Phosphoriboisomerase A) (PRI); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (231 aa) |
| | fumC | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa) |
| | gntZ | 6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (475 aa) |
| | NT26_2002 | MetF protein-like. (304 aa) |
| | gcvT-2 | Glycine cleavage system T protein, aminomethyltransferase; Belongs to the GcvT family. (470 aa) |
| | hom | Homoserine dehydrogenase (HDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (440 aa) |
| | NT26_2047 | Serine acetyltransferase; Function of strongly homologous gene; enzyme. (274 aa) |
| | NT26_2050 | Monooxygenase FAD-binding. (387 aa) |
| | ehhadh | Peroxisomal bifunctional enzyme [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; 3-hydroxyacyl-CoA dehydrogenase]. (646 aa) |
| | paaB | Enoyl-CoA hydratase/isomerase PhaB; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (264 aa) |
| | paaK | phenylacetyl-CoA ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (436 aa) |
| | maoC | Fused aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (689 aa) |
| | NT26_2070 | Phenylacetic acid catabolic family protein. (256 aa) |
| | paaE | Putative phenylacetic acid degradation NADH oxidoreductase paaE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (358 aa) |
| | paaD | Phenylacetic acid degradation protein paaD. (174 aa) |
| | paaC | Phenylacetic acid degradation protein paaC; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (260 aa) |
| | paaB-2 | Phenylacetic acid degradation protein paaB; Function of homologous gene experimentally demonstrated in an other organism; putative enzyme. (94 aa) |
| | paaA | Phenylacetic acid degradation protein paaA; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (333 aa) |
| | nthB | Nitrile hydratase subunit beta (Nitrilase) (NHase); NHase catalyzes the hydration of various nitrile compounds to the corresponding amides; Belongs to the nitrile hydratase subunit beta family. (219 aa) |
| | nthA | Nitrile hydratase subunit alpha (Nitrilase) (NHase); Function of strongly homologous gene; enzyme. (214 aa) |
| | NT26_2101 | Phosphoserine phosphatase (PSP) (O-phosphoserine phosphohydrolase) (PSPase) (modular protein). (532 aa) |
| | pfp | Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (403 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (297 aa) |
| | NT26_2189 | Glutamine synthetase catalytic region. (456 aa) |
| | gabD-2 | Succinate-semialdehyde dehydrogenase [NADP+]; Belongs to the aldehyde dehydrogenase family. (490 aa) |
| | fabG-3 | 3-oxoacyl-[acyl-carrier-protein] reductase. (251 aa) |
| | NT26_2275 | Alcohol dehydrogenase zinc-binding domain protein. (346 aa) |
| | nemA | N-ethylmaleimide reductase. (372 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa) |
| | fhs | Formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (556 aa) |
| | kdgK | 2-dehydro-3-deoxygluconokinase. (303 aa) |
| | ddh | 2-hydroxyacid dehydrogenase homolog; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (336 aa) |
| | betB-2 | Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (489 aa) |
| | xdhA | Xanthine dehydrogenase protein. (490 aa) |
| | xdhB | Xanthine dehydrogenase protein, B subunit. (778 aa) |
| | NT26_2480 | Putative Transthyretin-like protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (118 aa) |
| | ureC | Urease alpha subunit (Urea amidohydrolase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (569 aa) |
| | ureB | Urease beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the urease beta subunit family. (101 aa) |
| | ureA | Urease gamma subunit (Urea amidohydrolase gamma subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the urease gamma subunit family. (100 aa) |
| | NT26_2571 | Putative Aldehyde dehydrogenase (NAD(+)); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (475 aa) |
| | lpdV | Homologs of previously reported genes of unknown function. (464 aa) |
| | soxD | Sulfur dehydrogenase sub-unit SoxD precursor; Function of strongly homologous gene; enzyme. (381 aa) |
| | soxC | Sulfur dehydrogenase molybdo-enzyme sub-unit SoxC precursor; Function of strongly homologous gene; enzyme. (420 aa) |
| | soxB | Mn-dependent sulfate thiohydrolase, sulfur oxidation protein SoxB; Function of strongly homologous gene; enzyme; Belongs to the 5'-nucleotidase family. (566 aa) |
| | soxA | Cytochrome c551 diheme subunit, sulfur oxidizing protein SoxA precursor; Function of homologous gene experimentally demonstrated in an other organism; carrier. (284 aa) |
| | soxZ | Sulfur oxidation protein SoxZ; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (109 aa) |
| | soxY | Sulfur oxidation protein SoxY, thiosulfate-binding subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (149 aa) |
| | soxX | Cytochrome c551 monoheme subunit, sulfur oxidizing protein SoxX precursor; Function of homologous gene experimentally demonstrated in an other organism; carrier. (154 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (393 aa) |
| | cbbT-2 | Transketolase (TK); Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (651 aa) |
| | cbbG | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa) |
| | cbbK | Phosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | NT26_2688 | Putative fructose-bisphosphate aldolase class 1, Fda; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (298 aa) |
| | pyk | Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. (479 aa) |
| | gltD | Glutamate synthase [NADPH] small chain, (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (484 aa) |
| | gltB | Glutamate synthase [NADPH] large chain (NADPH-GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1572 aa) |
| | ald-2 | Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (348 aa) |
| | pgm | Phosphoglucomutase. (542 aa) |
| | NT26_2790 | Putative tautomerase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 4-oxalocrotonate tautomerase family. (72 aa) |
| | eda | KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase]. (212 aa) |
| | gltX | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (484 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (319 aa) |
| | gcdH | glutaryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (395 aa) |
| | gabD-3 | Succinate-semialdehyde dehydrogenase [NADP+]. (496 aa) |
| | Hibch | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial. (353 aa) |
| | NT26_2991 | Homologs of previously reported genes of unknown function. (273 aa) |
| | bsdB | Phenolic acid decarboxylase subunit B; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (193 aa) |
| | ppsA | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (798 aa) |
| | adhA-2 | Putative alcohol dehydrogenase adhA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (327 aa) |
| | NT26_3018 | Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (256 aa) |
| | NT26_3059 | Putative dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (573 aa) |
| | NT26_3064 | Xylose isomerase domain protein TIM barrel. (289 aa) |
| | NT26_3111 | Aldehyde dehydrogenase family 7 member A1 homolog; Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family. (513 aa) |
| | cobA | Uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (263 aa) |
| | NT26_3185 | Metapyrocatechase; catechol 2,3-dioxygenase. (318 aa) |
| | ligK | 4-carboxy-4-hydroxy-2-oxoadipate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (223 aa) |
| | NT26_3187 | Homologs of previously reported genes of unknown function. (342 aa) |
| | cysG-2 | Siroheme synthase [Includes: Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (499 aa) |
| | nasE | Assimilatory nitrite reductase [NAD(P)H] small subunit. (117 aa) |
| | nasD | Nitrite reductase [NAD(P)H]; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (818 aa) |
| | NT26_3230 | Gluconolactonase protein. (309 aa) |
| | idhA | Inositol 2-dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (328 aa) |
| | NT26_3243 | Fructokinase-1. (660 aa) |
| | NT26_3244 | Putative malonic semialdehyde oxidative decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the TPP enzyme family. (610 aa) |
| | mocC | Rhizopine catabolism protein mocC. (301 aa) |
| | iolB | 5-deoxy-glucuronate isomerase. (272 aa) |
| | NT26_3255 | Sulphur oxidation protein SoxZ. (271 aa) |
| | gfa | Glutathione-dependent formaldehyde-activating enzyme (S-(hydroxymethyl)glutathione synthase); Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family. (191 aa) |
| | adhC-2 | S-(hydroxymethyl)glutathione dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (375 aa) |
| | mxaF | Methanol dehydrogenase large subunit homolog; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (634 aa) |
| | NT26_3293 | Dihydrodipicolinate synthetase; Belongs to the DapA family. (300 aa) |
| | hyuE | Hydantoin racemase; Function of strongly homologous gene; enzyme. (249 aa) |
| | NT26_3338 | Orn/DAP/Arg decarboxylase 2. (410 aa) |
| | NT26_3341 | Serine acetyltransferase CysE, putative precurssor; Function of strongly homologous gene; enzyme. (210 aa) |
| | lysC | Aspartokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartokinase family. (424 aa) |
| | NT26_3400 | Acetyl-CoA synthetase protein. (545 aa) |
| | hbdA | 3-hydroxybutyryl-CoA dehydrogenase (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD); Function of strongly homologous gene; enzyme. (294 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (422 aa) |
| | accA | acetylCoA carboxylase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (340 aa) |
| | fdsD | NAD-dependent formate dehydrogenase delta subunit. (114 aa) |
| | fdsA | Formate dehydrogenase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (959 aa) |
| | fdsB | Putative formate dehydrogenase beta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (518 aa) |
| | fdsG | Putative formate dehydrogenase gamma subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (159 aa) |
| | lpd | Dihydrolipoyl dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (468 aa) |
| | sucB | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (414 aa) |
| | sucA | 2-oxoglutarate dehydrogenase E1 component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (999 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit, NAD(P)-binding; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (301 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa) |
| | sdhB | Succinate dehydrogenase, Fe-S protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa) |
| | sdhA | Succinate dehydrogenase flavoprotein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (617 aa) |
| | sdhD | Succinate dehydrogenase, hydrophobic membrane anchor protein. (126 aa) |
| | sdhC | Succinate dehydrogenase cytochrome b556 subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (139 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (309 aa) |
| | NT26_3506 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (239 aa) |
| | acnA | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (882 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (296 aa) |
| | Galm | Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (337 aa) |
| | phbB | acetoacetyl-coA reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (241 aa) |
| | phbA | Acetyl-CoA acetyltransferase with thiolase domain (Acetoacetyl-CoA thiolase); Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | pyc | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1153 aa) |
| | NT26_3623 | Uncharacterized aminotransferase y4uB; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa) |
| | NT26_3632 | Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa) |
| | norC | Nitric-oxide reductase subunit C (Nitric oxide reductase cytochrome c subunit) (NOR small subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (150 aa) |
| | norB | Nitric-oxide reductase subunit B (Nitric oxide reductase cytochrome b subunit) (NOR large subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the heme-copper respiratory oxidase family. (447 aa) |
| | nirK | Nitrite reductase, copper-containing; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the multicopper oxidase family. (376 aa) |
| | NT26_3678 | Ribose-phosphate pyrophosphokinase. (324 aa) |
| | napB | Periplasmic nitrate reductase, small subunit diheme cytochrome c (napB); Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. (153 aa) |
| | napA | Periplasmic nitrate reductase, large subunit (NapA); Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (834 aa) |
| | NT26_3710 | Mandelate racemase / muconate lactonizing enzyme family protein. (400 aa) |
| | glnII | Glutamine synthetase II (Glutamate--ammonia ligase II) (GSII); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (346 aa) |
| | pcaF | Beta-ketoadipyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa) |
| | scoB | 3-oxoadipate CoA-transferase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (233 aa) |
| | scoA | 3-oxoadipate CoA-transferase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (235 aa) |
| | pcaB | 3-carboxy-cis,cis-muconate cycloisomerase protein. (352 aa) |
| | pcaG | Protocatechuate 3,4-dioxygenase alpha chain. (205 aa) |
| | pcaH | Protocatechuate 3,4-dioxygenase beta chain. (246 aa) |
| | pcaC | 4-carboxymuconolactone decarboxylase. (146 aa) |
| | pcaD | Beta-ketoadipate enol-lactone hydrolase protein. (265 aa) |
| | ttuD | Putative hydroxypyruvate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (418 aa) |
| | phbH | 4-hydroxybenzoate hydroxylase (4-hydroxybenzoate-3-monooxygenase); Function of strongly homologous gene; enzyme. (389 aa) |
| | pfkB | 1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family. (326 aa) |
| | cat | Succinyl-CoA:coenzyme A transferase. (497 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa) |
| | NT26_3803 | NAD-specific glutamate dehydrogenase protein. (1590 aa) |
| | acsA-2 | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (302 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (536 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (723 aa) |
| | NT26_3905 | Homologs of previously reported genes of unknown function. (335 aa) |
| | NT26_3906 | Uncharacterized hydrolase/peptidase y4tM. (392 aa) |
| | NT26_3910 | Uncharacterized aminotransferase y4uB; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (473 aa) |
| | gabD-4 | Succinate-semialdehyde dehydrogenase [NADP+]. (492 aa) |
| | bhbA | Methylmalonyl-CoA mutase. (711 aa) |
| | PCCA | Propionyl-CoA carboxylase alpha chain, mitochondrial. (670 aa) |
| | NT26_3940 | Putative propionyl-CoA carboxylase beta chain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (510 aa) |
| | Bdh | 3-hydroxybutyrate dehydrogenase type 2. (247 aa) |
| | NT26_3982 | Putative acid-thiol ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (543 aa) |
| | ehhadh-2 | Peroxisomal bifunctional enzyme [Includes: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA isomerase; 3-hydroxyacyl-CoA dehydrogenase]; Belongs to the enoyl-CoA hydratase/isomerase family. (658 aa) |
| | NT26_3993 | NADPH dehydrogenase; Function of strongly homologous gene; enzyme. (770 aa) |
| | NT26_4046 | Putative D-isomer specific 2-hydroxyacid dehydrogenases family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (334 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (211 aa) |
| | dapB | Dihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa) |
| | glk | Glucokinase; Belongs to the bacterial glucokinase family. (344 aa) |
| | mgsA | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (122 aa) |
| | NT26_4091 | 2-hydroxyacid dehydrogenase. (317 aa) |
| | NT26_4110 | Dimethylmenaquinone methyltransferase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (338 aa) |
| | NT26_4287 | Cysteine synthase, chloroplastic/chromoplastic. (322 aa) |
| | fadB | Putative enoyl-CoA hydratase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa) |
