(68 nodes) Actin cytoskeleton network (Macrophomina phaseolina)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	MPH_00306	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (829 aa)
	MPH_08302	Calponin-homology (CH) domain-containing protein. (651 aa)
	MPH_10060	Zn(2)-C6 fungal-type domain-containing protein. (745 aa)
	MPH_12893	Glycoside hydrolase family 5; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (446 aa)
	MPH_10075	VHS domain-containing protein. (417 aa)
	MPH_12703	Uncharacterized protein. (147 aa)
	MPH_12724	Peptidase M3A/M3B. (656 aa)
	MPH_09768	IQ motif EF-hand binding site. (1800 aa)
	MPH_08727	Sulfate transporter/antisigma-factor antagonist STAS. (813 aa)
	MPH_08630	Cytochrome b5; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1857 aa)
	MPH_11132	Uncharacterized protein. (659 aa)
	MPH_08197	Uncharacterized protein. (161 aa)
	MPH_08140	Methyltransferase type 12. (460 aa)
	MPH_08155	Arf GTPase activating protein. (660 aa)
	MPH_07992	IQ motif EF-hand binding site; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2408 aa)
	MPH_10072	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (209 aa)
	MPH_09813	Actin-binding cofilin/tropomyosin type. (129 aa)
	MPH_04909	Zinc finger N-recognin protein. (596 aa)
	MPH_06857	IQ motif EF-hand binding site; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1577 aa)
	MPH_04786	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (169 aa)
	MPH_06824	Actinin-type actin-binding conserved site. (641 aa)
	MPH_08853	Calcium-binding EF-hand. (353 aa)
	MPH_08504	EPS15-like protein. (403 aa)
	MPH_05684	Dynactin p62. (591 aa)
	MPH_07819	Inositol polyphosphate-related phosphatase. (1045 aa)
	MPH_13134	Peptidase M3A/M3B. (146 aa)
	MPH_07144	SH3 domain-containing protein. (1245 aa)
	MPH_02319	Transglutaminase-like protein. (663 aa)
	MPH_03416	Actin-like protein; Belongs to the actin family. (439 aa)
	MPH_14249	Actin-like protein. (71 aa)
	MPH_08814	Cupin RmlC-type. (507 aa)
	MPH_08174	EPS15-like protein. (1415 aa)
	MPH_07886	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (363 aa)
	MPH_05693	Protein kinase domain-containing protein. (1060 aa)
	MPH_11846	Coronin; Belongs to the WD repeat coronin family. (607 aa)
	MPH_02459	Uncharacterized protein. (1045 aa)
	MPH_02360	Fps/Fes/Fer/CIP4-like protein. (927 aa)
	MPH_12145	Glutamyl-tRNA synthetase. (196 aa)
	MPH_02229	EPS15-like protein. (224 aa)
	MPH_11940	Tannase/feruloyl esterase. (327 aa)
	MPH_10182	DUF2183 domain-containing protein. (414 aa)
	MPH_01875	Actin-like protein; Belongs to the actin family. (389 aa)
	MPH_01640	EPS15-like protein. (1368 aa)
	MPH_09665	Spa2-like protein. (920 aa)
	MPH_01494	Actinin-type actin-binding conserved site. (651 aa)
	MPH_10867	C2 calcium-dependent membrane targeting. (766 aa)
	MPH_10798	Uncharacterized protein. (866 aa)
	MPH_08927	Glycoside hydrolase family 5; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (413 aa)
	MPH_08631	Cytochrome b5. (1790 aa)
	MPH_00353	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily. (2032 aa)
	MPH_00653	Dynamitin subunit 2. (212 aa)
	MPH_08730	BTB/POZ-like protein. (342 aa)
	MPH_01567	Actin-like protein. (375 aa)
	MPH_06921	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (189 aa)
	MPH_06485	Uncharacterized protein. (537 aa)
	MPH_00666	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (318 aa)
	MPH_00362	Lanthionine synthetase C-like protein. (285 aa)
	MPH_03103	Glycoside hydrolase family 5; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (416 aa)
	MPH_05681	Glycoside hydrolase family 5; Belongs to the glycosyl hydrolase 5 (cellulase A) family. (577 aa)
	MPH_10885	Actin-like protein; Belongs to the actin family. (498 aa)
	MPH_01876	Fps/Fes/Fer/CIP4-like protein. (728 aa)
	MPH_10073	Uncharacterized protein. (679 aa)
	MPH_04385	Uncharacterized protein. (435 aa)
	MPH_09695	Pyridoxal phosphate-dependent enzyme beta subunit. (209 aa)
	MPH_03975	Late secretory pathway protein AVL9. (673 aa)
	MPH_03760	Dynamin_M domain-containing protein. (334 aa)
	MPH_03759	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (292 aa)
	MPH_03524	Zinc finger LIM-type protein. (784 aa)

Your Current Organism:

Macrophomina phaseolina

NCBI taxonomy Id: 1126212
Other names: M. phaseolina MS6, Macrophomina phaseolina MS6, Macrophomina phaseolina str. MS6, Macrophomina phaseolina strain MS6

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MPH_00306	MPH_00653	K2RIA8	K2SAX6	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Dynamitin subunit 2.	0.986
MPH_00306	MPH_00666	K2RIA8	K2SZL2	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.866
MPH_00306	MPH_01494	K2RIA8	K2RFC7	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actinin-type actin-binding conserved site.	0.932
MPH_00306	MPH_01567	K2RIA8	K2SFB1	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin-like protein.	0.945
MPH_00306	MPH_01875	K2RIA8	K2RE33	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin-like protein; Belongs to the actin family.	0.869
MPH_00306	MPH_03416	K2RIA8	K2S3I0	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin-like protein; Belongs to the actin family.	0.925
MPH_00306	MPH_04786	K2RIA8	K2RTA4	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.	0.724
MPH_00306	MPH_05684	K2RIA8	K2RWM7	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Dynactin p62.	0.985
MPH_00306	MPH_06824	K2RIA8	K2RTI1	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actinin-type actin-binding conserved site.	0.786
MPH_00306	MPH_06857	K2RIA8	K2RT41	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	IQ motif EF-hand binding site; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.498
MPH_00306	MPH_06921	K2RIA8	K2SGJ2	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.862
MPH_00306	MPH_07886	K2RIA8	K2QYI5	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family.	0.641
MPH_00306	MPH_08197	K2RIA8	K2RPC7	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Uncharacterized protein.	0.411
MPH_00306	MPH_09695	K2RIA8	K2S8D4	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Pyridoxal phosphate-dependent enzyme beta subunit.	0.980
MPH_00306	MPH_10072	K2RIA8	K2RRH2	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.990
MPH_00306	MPH_10073	K2RIA8	K2S7I4	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Uncharacterized protein.	0.980
MPH_00306	MPH_10885	K2RIA8	K2S5M4	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin-like protein; Belongs to the actin family.	0.978
MPH_00306	MPH_11846	K2RIA8	K2R9J5	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Coronin; Belongs to the WD repeat coronin family.	0.609
MPH_00306	MPH_11940	K2RIA8	K2RDB8	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Tannase/feruloyl esterase.	0.957
MPH_00306	MPH_14249	K2RIA8	K2QGD8	WASH complex F-actin capping protein beta subunit; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Actin-like protein.	0.945