STRINGSTRING
AJY73569.1 AJY73569.1 speD speD AJY77452.1 AJY77452.1 AJY73744.1 AJY73744.1 AJY73745.1 AJY73745.1 AJY73746.1 AJY73746.1 AJY73893.1 AJY73893.1 AJY73985.1 AJY73985.1 AJY74101.1 AJY74101.1 AJY74296.1 AJY74296.1 AJY77559.1 AJY77559.1 mmuM mmuM AJY74379.1 AJY74379.1 AJY77568.1 AJY77568.1 AJY74492.1 AJY74492.1 AJY74495.1 AJY74495.1 metK metK mtaD mtaD AJY74723.1 AJY74723.1 AJY77622.1 AJY77622.1 metN metN AJY74962.1 AJY74962.1 AJY74981.1 AJY74981.1 speE speE AJY75065.1 AJY75065.1 mtaD-2 mtaD-2 AJY75174.1 AJY75174.1 AJY77694.1 AJY77694.1 cysS cysS cysH cysH sat sat AJY75366.1 AJY75366.1 cysI cysI mtnA mtnA AJY75424.1 AJY75424.1 mtaD-3 mtaD-3 AJY75454.1 AJY75454.1 AJY75455.1 AJY75455.1 AJY75456.1 AJY75456.1 AJY75457.1 AJY75457.1 metN-2 metN-2 AJY75459.1 AJY75459.1 AJY75460.1 AJY75460.1 AJY77722.1 AJY77722.1 AJY75461.1 AJY75461.1 AJY75462.1 AJY75462.1 AJY75463.1 AJY75463.1 AJY75782.1 AJY75782.1 AJY75783.1 AJY75783.1 cysW cysW AJY75785.1 AJY75785.1 metAA metAA AJY75820.1 AJY75820.1 AJY75821.1 AJY75821.1 AJY75886.1 AJY75886.1 AJY75927.1 AJY75927.1 mtnA-2 mtnA-2 mtnK mtnK speH speH AJY76075.1 AJY76075.1 AJY76214.1 AJY76214.1 AJY76260.1 AJY76260.1 ahcY ahcY AJY76427.1 AJY76427.1 AJY77873.1 AJY77873.1 AJY76798.1 AJY76798.1 AJY76844.1 AJY76844.1 AJY76872.1 AJY76872.1 metE metE AJY76899.1 AJY76899.1 AJY76900.1 AJY76900.1 AJY77068.1 AJY77068.1 mtnD mtnD AJY77122.1 AJY77122.1 mtnW mtnW mtnX mtnX mtnB mtnB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJY73569.1Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
speDS-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. (270 aa)
AJY77452.1Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
AJY73744.1ABC transporter; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family. (354 aa)
AJY73745.1Sulfate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
AJY73746.1Sulfate ABC transporter permease; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (270 aa)
AJY73893.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (314 aa)
AJY73985.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa)
AJY74101.1S-adenosylhomocysteine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
AJY74296.1DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
AJY77559.1Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
mmuMConverts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
AJY74379.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
AJY77568.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
AJY74492.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
AJY74495.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (400 aa)
mtaDN-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. (445 aa)
AJY74723.1Methionine ABC transporter ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nlpA lipoprotein family. (282 aa)
AJY77622.1Methionine ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
metNMethionine ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (338 aa)
AJY74962.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (313 aa)
AJY74981.13-mercaptopyruvate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (275 aa)
AJY75065.1Aminotransferase class I and II; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
mtaD-2N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. (428 aa)
AJY75174.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)
AJY77694.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
cysScysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (491 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (230 aa)
satATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
AJY75366.1Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (607 aa)
cysISulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (573 aa)
mtnAMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (371 aa)
AJY75424.1Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
mtaD-3N-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. (441 aa)
AJY75454.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa)
AJY75455.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (60 aa)
AJY75456.1Methionine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nlpA lipoprotein family. (278 aa)
AJY75457.1Metal ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
metN-2Methionine ABC transporter ATP-binding protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (334 aa)
AJY75459.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
AJY75460.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
AJY77722.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
AJY75461.1Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
AJY75462.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
AJY75463.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
AJY75782.1Sulfate transporter subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
AJY75783.1Sulfate transporter; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. (277 aa)
cysWPart of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
AJY75785.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (62 aa)
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (305 aa)
AJY75820.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
AJY75821.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
AJY75886.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
AJY75927.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
mtnA-2Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (359 aa)
mtnKMethylthioribose kinase; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (403 aa)
speHS-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (132 aa)
AJY76075.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
AJY76214.1Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
AJY76260.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
ahcYS-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (420 aa)
AJY76427.1MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (234 aa)
AJY77873.1Homocysteine methyltransferase; Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. (664 aa)
AJY76798.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
AJY76844.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (79 aa)
AJY76872.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (763 aa)
AJY76899.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
AJY76900.1SAM-dependent methyltransferase; Could be a S-adenosyl-L-methionine-dependent methyltransferase. (216 aa)
AJY77068.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1146 aa)
mtnDAcireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (180 aa)
AJY77122.1Aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
mtnWConverts 2,3-diketo-5-methylthiopentyl-1-phosphate into 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate; involved in methionine salvage; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
mtnX2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate phosphatase; Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). (225 aa)
mtnBMethylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. (216 aa)
Your Current Organism:
Paenibacillus beijingensis
NCBI taxonomy Id: 1126833
Other names: ACCC 03082, DSM 24997, P. beijingensis, Paenibacillus sp. 7188, strain 7188
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