STRINGSTRING
AJY74495.1 AJY74495.1 glyA-2 glyA-2 AJY74696.1 AJY74696.1 AJY74883.1 AJY74883.1 AJY74962.1 AJY74962.1 serS serS AJY74981.1 AJY74981.1 AJY75174.1 AJY75174.1 AJY77694.1 AJY77694.1 cysH cysH AJY75366.1 AJY75366.1 AJY74492.1 AJY74492.1 gcvPB-2 gcvPB-2 gcvPA-2 gcvPA-2 gcvT-2 gcvT-2 glyA glyA gcvH-2 gcvH-2 AJY77568.1 AJY77568.1 AJY77542.1 AJY77542.1 AJY74173.1 AJY74173.1 AJY74164.1 AJY74164.1 gcvPB gcvPB gcvPA gcvPA gcvT gcvT gcvH gcvH AJY73985.1 AJY73985.1 AJY73893.1 AJY73893.1 AJY73794.1 AJY73794.1 AJY73569.1 AJY73569.1 cysI cysI metAA metAA AJY75820.1 AJY75820.1 AJY75821.1 AJY75821.1 serC serC AJY75886.1 AJY75886.1 AJY75927.1 AJY75927.1 AJY75957.1 AJY75957.1 AJY76214.1 AJY76214.1 AJY76260.1 AJY76260.1 AJY76798.1 AJY76798.1 AJY76899.1 AJY76899.1 AJY77015.1 AJY77015.1 AJY77049.1 AJY77049.1 AJY77203.1 AJY77203.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJY74495.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
AJY74696.1seryl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
AJY74883.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
AJY74962.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (313 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa)
AJY74981.13-mercaptopyruvate sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
AJY75174.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa)
AJY77694.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (230 aa)
AJY75366.1Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (607 aa)
AJY74492.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
gcvPB-2Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (503 aa)
gcvPA-2Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (435 aa)
gcvT-2Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (369 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (419 aa)
gcvH-2Glycine cleavage system protein H; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family. (130 aa)
AJY77568.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
AJY77542.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (312 aa)
AJY74173.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (368 aa)
AJY74164.1Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
gcvPBGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. (485 aa)
gcvPAGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (452 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (368 aa)
gcvHGlycine cleavage system protein H; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family. (129 aa)
AJY73985.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (91 aa)
AJY73893.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (314 aa)
AJY73794.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)
AJY73569.1Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
cysISulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (573 aa)
metAAHomoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (305 aa)
AJY75820.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
AJY75821.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
serCMFS transporter; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (362 aa)
AJY75886.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
AJY75927.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
AJY75957.1Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (408 aa)
AJY76214.1Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
AJY76260.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
AJY76798.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
AJY76899.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
AJY77015.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
AJY77049.1Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (163 aa)
AJY77203.1D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)
Your Current Organism:
Paenibacillus beijingensis
NCBI taxonomy Id: 1126833
Other names: ACCC 03082, DSM 24997, P. beijingensis, Paenibacillus sp. 7188, strain 7188
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.