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AJY73348.1 AJY73348.1 AJY73353.1 AJY73353.1 AJY73411.1 AJY73411.1 AJY73495.1 AJY73495.1 AJY73667.1 AJY73667.1 leuB leuB ilvC ilvC AJY73794.1 AJY73794.1 zwf zwf AJY73969.1 AJY73969.1 AJY77493.1 AJY77493.1 zwf-2 zwf-2 AJY74028.1 AJY74028.1 AJY74173.1 AJY74173.1 AJY74175.1 AJY74175.1 hisD hisD AJY74198.1 AJY74198.1 AJY77542.1 AJY77542.1 AJY74326.1 AJY74326.1 AJY74379.1 AJY74379.1 AJY74595.1 AJY74595.1 ldh ldh ldh-2 ldh-2 guaB guaB hisD-2 hisD-2 aroE aroE AJY75344.1 AJY75344.1 AJY75395.1 AJY75395.1 AJY77740.1 AJY77740.1 AJY75597.1 AJY75597.1 AJY75717.1 AJY75717.1 AJY75937.1 AJY75937.1 AJY75999.1 AJY75999.1 mdh mdh AJY76075.1 AJY76075.1 AJY76133.1 AJY76133.1 AJY76137.1 AJY76137.1 AJY76138.1 AJY76138.1 AJY76142.1 AJY76142.1 AJY76143.1 AJY76143.1 AJY76228.1 AJY76228.1 aroE-2 aroE-2 AJY76355.1 AJY76355.1 murB murB AJY76415.1 AJY76415.1 dxr dxr AJY76643.1 AJY76643.1 AJY77917.1 AJY77917.1 AJY76751.1 AJY76751.1 AJY76802.1 AJY76802.1 mtlD mtlD AJY77002.1 AJY77002.1 mtlD-2 mtlD-2 AJY77128.1 AJY77128.1 gpsA gpsA AJY77203.1 AJY77203.1 AJY77218.1 AJY77218.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJY73348.1Diacetylchitobiose-6-phosphate hydrolase; Catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
AJY73353.1Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
AJY73411.1Alpha-galactosidase; Catalyses the hydrolysis of terminal non-reducing alpha-D-galactose residues in alpha-D-galactosides; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
AJY73495.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
AJY73667.1Glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (359 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (330 aa)
AJY73794.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (518 aa)
AJY73969.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
AJY77493.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
zwf-2Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (499 aa)
AJY74028.16-phosphogluconate dehydrogenase; Similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
AJY74173.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (368 aa)
AJY74175.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (421 aa)
AJY74198.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
AJY77542.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (312 aa)
AJY74326.1Alpha-galactosidase; Catalyses the hydrolysis of terminal non-reducing alpha-D-galactose residues in alpha-D-galactosides; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
AJY74379.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
AJY74595.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (285 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (317 aa)
ldh-2Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (317 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa)
hisD-2Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (282 aa)
AJY75344.1Alpha-galactosidase; Catalyses the hydrolysis of terminal non-reducing alpha-D-galactose residues in alpha-D-galactosides; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
AJY75395.1Acetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (868 aa)
AJY77740.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
AJY75597.12-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
AJY75717.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
AJY75937.1Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
AJY75999.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (314 aa)
AJY76075.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
AJY76133.1Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (313 aa)
AJY76137.1Bifunctional glyoxylate/hydroxypyruvate reductase B; Catalyzes the formation of glycolate from glyoxylate and glycerate from hydroxypyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)
AJY76138.1Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
AJY76142.1Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (366 aa)
AJY76143.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
AJY76228.1Fe-S oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
aroE-2Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (304 aa)
AJY76355.1Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (331 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (301 aa)
AJY76415.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (379 aa)
AJY76643.1Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
AJY77917.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
AJY76751.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
AJY76802.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
mtlDMannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
AJY77002.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
mtlD-2Mannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AJY77128.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (342 aa)
AJY77203.1D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa)
AJY77218.15-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (376 aa)
Your Current Organism:
Paenibacillus beijingensis
NCBI taxonomy Id: 1126833
Other names: ACCC 03082, DSM 24997, P. beijingensis, Paenibacillus sp. 7188, strain 7188
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