STRINGSTRING
dxs dxs AJY73316.1 AJY73316.1 AJY73508.1 AJY73508.1 AJY73569.1 AJY73569.1 AJY73614.1 AJY73614.1 AJY73616.1 AJY73616.1 AJY73634.1 AJY73634.1 AJY73639.1 AJY73639.1 AJY73693.1 AJY73693.1 AJY77453.1 AJY77453.1 AJY77329.1 AJY77329.1 AJY73802.1 AJY73802.1 AJY77473.1 AJY77473.1 hisC hisC AJY74333.1 AJY74333.1 hemL hemL AJY77568.1 AJY77568.1 AJY74399.1 AJY74399.1 dsdA dsdA glyA glyA ilvA ilvA argD argD glyA-2 glyA-2 AJY74674.1 AJY74674.1 AJY74693.1 AJY74693.1 AJY74719.1 AJY74719.1 bioA bioA AJY74722.1 AJY74722.1 AJY74778.1 AJY74778.1 AJY74847.1 AJY74847.1 AJY74883.1 AJY74883.1 AJY75065.1 AJY75065.1 AJY75099.1 AJY75099.1 AJY75184.1 AJY75184.1 AJY75198.1 AJY75198.1 AJY75420.1 AJY75420.1 AJY75649.1 AJY75649.1 AJY75820.1 AJY75820.1 AJY75821.1 AJY75821.1 serC serC AJY75847.1 AJY75847.1 AJY75877.1 AJY75877.1 AJY75886.1 AJY75886.1 AJY75904.1 AJY75904.1 AJY75927.1 AJY75927.1 AJY75957.1 AJY75957.1 hemL-2 hemL-2 AJY76214.1 AJY76214.1 AJY76260.1 AJY76260.1 AJY76267.1 AJY76267.1 AJY76379.1 AJY76379.1 AJY76537.1 AJY76537.1 hisC-2 hisC-2 AJY76680.1 AJY76680.1 AJY76758.1 AJY76758.1 AJY76773.1 AJY76773.1 rocD rocD AJY76789.1 AJY76789.1 AJY76798.1 AJY76798.1 AJY76808.1 AJY76808.1 rocD-2 rocD-2 dsdA-2 dsdA-2 AJY76899.1 AJY76899.1 AJY77971.1 AJY77971.1 AJY76976.1 AJY76976.1 AJY77015.1 AJY77015.1 AJY77038.1 AJY77038.1 AJY77068.1 AJY77068.1 odhA odhA AJY77122.1 AJY77122.1 lysA lysA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (631 aa)
AJY73316.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. (605 aa)
AJY73508.1Amino acid racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (715 aa)
AJY73569.1Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
AJY73614.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (508 aa)
AJY73616.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
AJY73634.1Aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
AJY73639.1Catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
AJY73693.1Acetolactate synthase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (581 aa)
AJY77453.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
AJY77329.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
AJY73802.1Ornithine--oxo-acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (419 aa)
AJY77473.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (375 aa)
hisCHistidinol-phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (367 aa)
AJY74333.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
AJY77568.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
AJY74399.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (383 aa)
dsdASerine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the serine/threonine dehydratase family. DsdA subfamily. (486 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (419 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (422 aa)
argDAcetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (396 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
AJY74674.1Catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
AJY74693.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
AJY74719.18-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (395 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (443 aa)
AJY74722.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
AJY74778.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (451 aa)
AJY74847.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
AJY74883.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
AJY75065.1Aminotransferase class I and II; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
AJY75099.1Hypothetical protein; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. (286 aa)
AJY75184.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
AJY75198.1Ethanolamine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the EutC family. (240 aa)
AJY75420.14-aminobutyrate aminotransferase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (428 aa)
AJY75649.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
AJY75820.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
AJY75821.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
serCMFS transporter; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (362 aa)
AJY75847.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
AJY75877.1Pyridoxal-5'-phosphate-dependent protein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
AJY75886.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
AJY75904.1Class III aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (431 aa)
AJY75927.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
AJY75957.1Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (408 aa)
hemL-2Glutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
AJY76214.1Methionine gamma-lyase; Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
AJY76260.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
AJY76267.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family. (394 aa)
AJY76379.1Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (237 aa)
AJY76537.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
hisC-2Histidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (361 aa)
AJY76680.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
AJY76758.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (558 aa)
AJY76773.1Putrescine--2-oxoglutarate aminotransferase; Catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
rocDOrnithine--oxo-acid aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (399 aa)
AJY76789.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
AJY76798.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
AJY76808.1Pyridoxal-5'-phosphate-dependent protein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
rocD-2Ornithine--oxo-acid aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (399 aa)
dsdA-2Serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the serine/threonine dehydratase family. DsdA subfamily. (453 aa)
AJY76899.1Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
AJY77971.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
AJY76976.1Amino acid aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction. (279 aa)
AJY77015.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
AJY77038.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
AJY77068.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1146 aa)
odhA2-oxoglutarate dehydrogenase; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). (955 aa)
AJY77122.1Aminotransferase; Produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (449 aa)
Your Current Organism:
Paenibacillus beijingensis
NCBI taxonomy Id: 1126833
Other names: ACCC 03082, DSM 24997, P. beijingensis, Paenibacillus sp. 7188, strain 7188
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