STRINGSTRING
aroE-2 aroE-2 hutI hutI hutU hutU AJY73399.1 AJY73399.1 AJY73586.1 AJY73586.1 AJY73659.1 AJY73659.1 AJY73760.1 AJY73760.1 aroC aroC AJY73986.1 AJY73986.1 AJY77493.1 AJY77493.1 AJY74130.1 AJY74130.1 AJY74171.1 AJY74171.1 hutI-2 hutI-2 hutU-2 hutU-2 hutH hutH AJY77546.1 AJY77546.1 aspA aspA fumC fumC AJY74675.1 AJY74675.1 dapH dapH AJY74788.1 AJY74788.1 AJY74798.1 AJY74798.1 nadA nadA AJY77646.1 AJY77646.1 AJY74966.1 AJY74966.1 AJY74967.1 AJY74967.1 AJY77647.1 AJY77647.1 aroE aroE ppc ppc aroK aroK aroA aroA AJY77871.1 AJY77871.1 dapF dapF AJY77892.1 AJY77892.1 asd asd AJY76620.1 AJY76620.1 dapA dapA AJY76776.1 AJY76776.1 AJY76781.1 AJY76781.1 AJY76786.1 AJY76786.1 AJY76790.1 AJY76790.1 AJY76811.1 AJY76811.1 AJY76814.1 AJY76814.1 AJY76870.1 AJY76870.1 AJY76977.1 AJY76977.1 AJY77002.1 AJY77002.1 AJY77048.1 AJY77048.1 dapB dapB AJY77164.1 AJY77164.1 aroB aroB aroC-2 aroC-2 lysA lysA AJY77271.1 AJY77271.1 aroQ aroQ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aroE-2Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (304 aa)
hutIImidazolonepropionase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (553 aa)
AJY73399.1Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
AJY73586.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M20A family. (391 aa)
AJY73659.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
AJY73760.1Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (389 aa)
AJY73986.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1535 aa)
AJY77493.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
AJY74130.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
AJY74171.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
hutI-2Imidazolonepropionase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
hutU-2Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (552 aa)
hutHHistidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
AJY77546.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
aspAAspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
AJY74675.1N-acetyldiaminopimelate deacetylase; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (379 aa)
dapH2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (237 aa)
AJY74788.1Dihydrodipicolinate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (294 aa)
AJY74798.1Metal-dependent amidase/aminoacylase/carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (312 aa)
AJY77646.1Nicotinate-nucleotide pyrophosphorylase; Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (289 aa)
AJY74966.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (291 aa)
AJY74967.1Dienelactone hydrolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (128 aa)
AJY77647.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (282 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (934 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (156 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (430 aa)
AJY77871.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (281 aa)
AJY77892.1Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (345 aa)
AJY76620.1Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (406 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (290 aa)
AJY76776.1Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
AJY76781.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
AJY76786.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
AJY76790.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
AJY76811.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
AJY76814.1Proline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
AJY76870.1Aspartate-semialdehyde dehydrogenase; Catalyzes the formation of aspartate semialdehyde from aspartyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate-semialdehyde dehydrogenase family. (347 aa)
AJY76977.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
AJY77002.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
AJY77048.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (267 aa)
AJY77164.1Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (122 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (367 aa)
aroC-2Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (389 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (449 aa)
AJY77271.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (417 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa)
Your Current Organism:
Paenibacillus beijingensis
NCBI taxonomy Id: 1126833
Other names: ACCC 03082, DSM 24997, P. beijingensis, Paenibacillus sp. 7188, strain 7188
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